Effect of natural deprivation and unilateral eye patching on visual acuity of infants and children. Evoked potential measurements.

Evoked potential measurements of visual acuity were made on four children aged from 5 months to 8 years. They were deprived of normal visual stimulation by various disorders: unilateral aphakia from a congenital cataract, vitreous hemorrhage, polar cataract, and esotropia. In the two younger children, aged 5 and 15 months, respectively, the visual acuity improved when the eye had good optical imagery and declined with poor or no imagery. Reversal of the imagery to the contralateral eyes again brought large changes in opposite directions. In the two older children, aged 4 and 8 years, respectively, there were marked decreases in acuity in the patched eye, but little or no change in the unpatched eye. It is not know whether these differences are due to age or to the original kind of visual disorder, such as deprivation, occlusion, or strabismus, or are merely individual differences. It is clear, however, that some children exhibit large changes in acuity in response to visual deprivation or patching, or to its removal, in a readily reversible manner. Also, we have demonstrated that visually evoked potential acuities may be obtained from pediatric, clinical patients without regard to age, which may be useful in management of the conditions.

[1]  D. Mayer,et al.  Assessment of vision in young children: a new operant approach yields estimates of acuity. , 1980, Investigative ophthalmology & visual science.

[2]  R. Held,et al.  Strabismic amblyopia in infants. , 1979, American journal of optometry and physiological optics.

[3]  Richard Held,et al.  Infant visual acuity and its meridional variation , 1978, Vision Research.

[4]  M. Crawford,et al.  Morphological and physiological changes in the monkey visual system after short-term lid suture. , 1978, Investigative ophthalmology & visual science.

[5]  G. K. Noorden Application of Basic Research Data to Clinical Amblyopia , 1978 .

[6]  D. Mitchell,et al.  Recovery from the effects of monocular deprivation in kittens , 1977, The Journal of comparative neurology.

[7]  G. Pollak,et al.  Echo-detecting characteristics of neurons in inferior colliculus of unanesthetized bats. , 1977, Science.

[8]  M. R. Harter,et al.  Maturation of evoked potentials and visual preference in 6-45-day-old infants: effects of check size, visual acuity, and refractive error. , 1977, Electroencephalography and clinical neurophysiology.

[9]  H. Hartwig,et al.  [Stimulus deprivation amblyopia (author's transl)]. , 1976, Klinische Monatsblatter fur Augenheilkunde.

[10]  M S Banks,et al.  Sensitive period for the development of human binocular vision , 1975, Science.

[11]  O. Creutzfeldt,et al.  Squint and the development of binocularity in humans , 1975, Nature.

[12]  D. Teller,et al.  Visual acuity for vertical and diagonal gratings in human infants. , 1974, Vision research.

[13]  G. K. Noorden Original Articles: Experimental Amblyopia in Monkeys. Further Behavioral Observations and Clinical Correlations , 1973 .

[14]  R D Freeman,et al.  Meridional amblyopia: evidence for modification of the human visual system by early visual experience. , 1973, Vision research.

[15]  D. Hubel,et al.  The period of susceptibility to the physiological effects of unilateral eye closure in kittens , 1970, The Journal of physiology.

[16]  T. Wiesel,et al.  Consequences of monocular deprivation on visual behaviour in kittens , 1970, The Journal of physiology.

[17]  D. Hubel,et al.  SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE. , 1963, Journal of neurophysiology.

[18]  R. L. Frantz,et al.  Maturation of pattern vision in infants during the first six months. , 1962 .

[19]  D E Mitchell,et al.  The rate of recovery of vision after early monocular deprivation in kittens , 1978, The Journal of physiology.

[20]  S. Sokol,et al.  Pattern reversal visually evoked potentials in infants. , 1976, Investigative ophthalmology.

[21]  S. Awaya "Amblymopia in man,suggestive of stimulus deprivation amblyopia" (The strabismus symposium in Kyoto) , 1973 .