Molecular definition of breast tumor heterogeneity.

[1]  O. Kallioniemi,et al.  Identification of target genes in laryngeal squamous cell carcinoma by high-resolution copy number and gene expression microarray analyses , 2006, Oncogene.

[2]  N. Kapucuoglu,et al.  CD24 expression in ductal carcinoma in situ and invasive ductal carcinoma of breast: an immunohistochemistry-based pilot study. , 2006, Pathology, research and practice.

[3]  François Vaillant,et al.  Steroid hormone receptor status of mouse mammary stem cells. , 2006, Journal of the National Cancer Institute.

[4]  M. Lynch,et al.  Breast cancer, stem cells and prospects for therapy , 2006, Breast Cancer Research.

[5]  Tin-Lap Lee,et al.  Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes. , 2006, Genomics.

[6]  G. Dontu,et al.  Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. , 2006, Cancer research.

[7]  P. Schedin.  Pregnancy-associated breast cancer and metastasis , 2006, Nature Reviews Cancer.

[8]  M. Clarke,et al.  Stem Cells and Cancer: Two Faces of Eve , 2006, Cell.

[9]  K. Polyak.  Pregnancy and breast cancer: the other side of the coin. , 2006, Cancer cell.

[10]  W. Hahn,et al.  Roots and stems: stem cells in cancer , 2006, Nature Medicine.

[11]  T. Nikolskaya,et al.  A COMBINED APPROACH TO DRUG METABOLISM AND TOXICITY ASSESSMENT , 2006, Drug Metabolism and Disposition.

[12]  Max S Wicha,et al.  Cancer stem cells: an old idea--a paradigm shift. , 2006, Cancer research.

[13]  M. J. van de Vijver,et al.  Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. , 2006, Journal of the National Cancer Institute.

[14]  C. Arteaga.  Inhibition of TGFβ signaling in cancer therapy , 2006 .

[15]  C. Arteaga.  Inhibition of TGFbeta signaling in cancer therapy. , 2006, Current opinion in genetics & development.

[16]  H. Osada,et al.  Histone modification in the TGFβRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines , 2005 .

[17]  J. Sleeman,et al.  CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis. , 2005, Cancer research.

[18]  Cheng Li,et al.  Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis , 2005, PLoS Comput. Biol..

[19]  Catherine M. Verfaillie,et al.  The molecular repertoire of the 'almighty' stem cell , 2005, Nature Reviews Molecular Cell Biology.

[20]  Jun Yao,et al.  Distinct epigenetic changes in the stromal cells of breast cancers , 2005, Nature Genetics.

[21]  Sean Ekins,et al.  A novel method for generation of signature networks as biomarkers from complex high throughput data. , 2005, Toxicology letters.

[22]  R. Schneider-Broussard,et al.  Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2- cancer cells are similarly tumorigenic. , 2005, Cancer research.

[23]  Kirsten L. Greene,et al.  CpG methylation at promoter site −140 inactivates TGFβ2 receptor gene in prostate cancer , 2005, Cancer.

[24]  Danila Coradini,et al.  Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. , 2005, Cancer research.

[25]  G. Glinsky,et al.  Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. , 2005, The Journal of clinical investigation.

[26]  T. Nikolskaya,et al.  Biological networks and analysis of experimental data in drug discovery. , 2005, Drug discovery today.

[27]  Jose Russo,et al.  The protective role of pregnancy in breast cancer , 2005, Breast Cancer Research.

[28]  Michael Dean,et al.  Tumour stem cells and drug resistance , 2005, Nature Reviews Cancer.

[29]  Ariel J. Levine,et al.  TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells , 2005 .

[30]  Howard Y. Chang,et al.  Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[31]  A. Mercurio,et al.  The epithelial-mesenchymal tansition (EMT) and colorectal cancer progression , 2005, Cancer biology & therapy.

[32]  J. Foekens,et al.  Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer , 2005, The Lancet.

[33]  Maria Athelogou,et al.  Prevalence of CD44+/CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[34]  A. Howell,et al.  A putative human breast stem cell population is enriched for steroid receptor-positive cells. , 2005, Developmental biology.

[35]  Carlos L Arteaga,et al.  Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[36]  Ariel J. Levine,et al.  TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. , 2005, Development.

[37]  Stefani N. Thomas,et al.  Using proteomics and network analysis to elucidate the consequences of synaptic protein oxidation in a PS1 + AbetaPP mouse model of Alzheimer's disease. , 2005, Journal of Alzheimer's disease : JAD.

[38]  H. Osada,et al.  Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines. , 2005, Molecular carcinogenesis.

[39]  C. Eaves,et al.  Epithelial Progenitors in the Normal Human Mammary Gland , 2005, Journal of Mammary Gland Biology and Neoplasia.

[40]  Elaine Fuchs,et al.  Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche , 2004, Cell.

[41]  M. Vivanco,et al.  Growth and differentiation of progenitor/stem cells derived from the human mammary gland. , 2004, Experimental cell research.

[42]  Rameen Beroukhim,et al.  Molecular characterization of the tumor microenvironment in breast cancer. , 2004, Cancer cell.

[43]  Zewei Luo,et al.  Defective Expression of Transforming Growth Factor β Receptor Type II Is Associated with CpG Methylated Promoter in Primary Non-Small Cell Lung Cancer , 2004, Clinical Cancer Research.

[44]  C. Pilarsky,et al.  CD24 expression is a new prognostic marker in breast cancer. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[45]  L. Wakefield,et al.  The two faces of transforming growth factor β in carcinogenesis , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[46]  G. Dontu,et al.  In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. , 2003, Genes & development.

[47]  S. Morrison,et al.  Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[48]  Kornelia Polyak,et al.  Molecular markers in ductal carcinoma in situ of the breast. , 2003, Molecular cancer research : MCR.

[49]  L. Wakefield,et al.  The two faces of transforming growth factor beta in carcinogenesis. , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[50]  J. Massagué,et al.  Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. , 2003, Nature reviews. Cancer.

[51]  John T. Dimos,et al.  A Stem Cell Molecular Signature , 2002, Science.

[52]  D. Melton,et al.  "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells , 2002, Science.

[53]  Hermann Herbst,et al.  Common Adult Stem Cells in the Human Breast Give Rise to Glandular and Myoepithelial Cell Lineages: A New Cell Biological Concept , 2002, Laboratory Investigation.

[54]  Van,et al.  A gene-expression signature as a predictor of survival in breast cancer. , 2002, The New England journal of medicine.

[55]  D. Botstein,et al.  Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[56]  C. Eaves,et al.  Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. , 1998, Differentiation; research in biological diversity.

[57]  H. Moses,et al.  Regulation of differentiation by TFG-β , 1996 .

[58]  H. Moses,et al.  Regulation of differentiation by TGF-beta. , 1996, Current opinion in genetics & development.

[59]  S. Weremowicz,et al.  RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation , 1995, Molecular and cellular biology.

[60]  James M. Roberts,et al.  Cloning of p27 Kip1 , a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals , 1994, Cell.

[61]  S. Orkin,et al.  Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner , 1993, Molecular and cellular biology.