Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes
暂无分享,去创建一个
K. Muraszko | Horatiu Voicu | C. Lau | T. Man | M. Chintagumpala | J. Heth | Xiao-Nan Li | Xing Fan | M. Kogiso | Yulun Huang | Hua Mao | A. Adesina | S. Gurusiddappa | L. Perlaky | R. Dauser | P. Baxter | H. Leung | Xiumei Zhao | Zhigang Liu | Q. Lin | J. Su
[1] S. Hansen,et al. Clinical value of CD133 and nestin in patients with glioma: a population-based study. , 2014, International journal of clinical and experimental pathology.
[2] L. Yao,et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression , 2014, Journal of cellular and molecular medicine.
[3] M. Remke,et al. Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion , 2014, Acta neuropathologica communications.
[4] Y. Tu,et al. Combined aberrant expression of Bmi1 and EZH2 is predictive of poor prognosis in glioma patients , 2013, Journal of the Neurological Sciences.
[5] Y. Xiong,et al. A Bmi1-miRNAs Cross-Talk Modulates Chemotherapy Response to 5-Fluorouracil in Breast Cancer Cells , 2013, PloS one.
[6] C. Lau,et al. Intravenous injection of oncolytic picornavirus SVV-001 prolongs animal survival in a panel of primary tumor-based orthotopic xenograft mouse models of pediatric glioma. , 2013, Neuro-oncology.
[7] M. Serresi,et al. In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. , 2013, Cancer cell.
[8] Jiri Zavadil,et al. DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs , 2012, Proceedings of the National Academy of Sciences.
[9] M. Saleem,et al. CANCER STEM CELLS Concise Review: Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences , 2012 .
[10] David T. W. Jones,et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma , 2012, Nature.
[11] X. Wang,et al. Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells , 2012, Oncogene.
[12] T. Davis,et al. BMI1 as a novel target for drug discovery in cancer , 2011, Journal of cellular biochemistry.
[13] R. Wolff,et al. Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. , 2011, Mutation research.
[14] Susan M. Chang,et al. Pediatric brain tumors: Current treatment strategies and future therapeutic approaches , 2009, Neurotherapeutics.
[15] P. Dirks,et al. Brain tumor stem cells: The cancer stem cell hypothesis writ large , 2010, Molecular oncology.
[16] M. Korc. Driver mutations , 2010, Cancer biology & therapy.
[17] J. Rich,et al. Potential therapeutic implications of cancer stem cells in glioblastoma. , 2010, Biochemical pharmacology.
[18] Yan Li,et al. Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer. , 2010, European journal of cancer.
[19] Richard G Grundy,et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[20] P. Rao,et al. A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo. , 2010, Neuro-oncology.
[21] Libing Song,et al. Oncoprotein Bmi-1 renders apoptotic resistance to glioma cells through activation of the IKK-nuclear factor-kappaB Pathway. , 2010, The American journal of pathology.
[22] C. Kramm,et al. Intensive chemotherapy improves survival in pediatric high‐grade glioma after gross total resection: results of the HIT‐GBM‐C protocol , 2010, Cancer.
[23] J. Poyet,et al. Targeting AAC-11 in cancer therapy , 2010, Expert opinion on therapeutic targets.
[24] Guido Nikkhah,et al. NOTCH Pathway Blockade Depletes CD133‐Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts , 2009, Stem cells.
[25] Wenlin Huang,et al. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells. , 2009, The Journal of clinical investigation.
[26] Deric M. Park,et al. Biology of glioma cancer stem cells , 2009, Molecules and cells.
[27] G. Bernier,et al. BMI1 Sustains Human Glioblastoma Multiforme Stem Cell Renewal , 2009, The Journal of Neuroscience.
[28] I. Radovanovic,et al. Limits of CD133 as a marker of glioma self‐renewing cells , 2009, International journal of cancer.
[29] F. Zhou,et al. Expression of Bmi-1 is a prognostic marker in bladder cancer , 2009, BMC Cancer.
[30] Tao Song,et al. Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients , 2008, Journal of experimental & clinical cancer research : CR.
[31] M. Dowsett,et al. ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2. , 2008, Endocrine-related cancer.
[32] D. Ellison,et al. Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. , 2008, Neoplasia.
[33] S. Bidlingmaier,et al. The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells , 2008, Journal of Molecular Medicine.
[34] K. Wong,et al. Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+ Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma , 2008, Stem cells.
[35] Henry Adams,et al. REST maintains self-renewal and pluripotency of embryonic stem cells , 2008, Nature.
[36] G. Sommer,et al. Reference , 2008 .
[37] P. Lichter,et al. Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients , 2008, Clinical Cancer Research.
[38] Ke Pan,et al. Increased polycomb-group oncogene Bmi-1 expression correlates with poor prognosis in hepatocellular carcinoma , 2008, Journal of Cancer Research and Clinical Oncology.
[39] S. Albrecht,et al. Gene Expression Profiling from Formalin-Fixed Paraffin-Embedded Tumors of Pediatric Glioblastoma , 2007, Clinical Cancer Research.
[40] O. van Tellingen,et al. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma. , 2007, Cancer cell.
[41] Alexander Brawanski,et al. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. , 2007, Cancer research.
[42] P. Liberski,et al. Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[43] Mark W. Dewhirst,et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response , 2006, Nature.
[44] Jun-Yuan Ji,et al. Functional Identification of Api5 as a Suppressor of E2F-Dependent Apoptosis In Vivo , 2006, PLoS genetics.
[45] R. Jalali,et al. Leptomeninges as a site of relapse in locally controlled, diffuse pontine glioma with review of literature , 2006, Child's Nervous System.
[46] C. Lau,et al. Valproic Acid Prolongs Survival Time of Severe Combined Immunodeficient Mice Bearing Intracerebellar Orthotopic Medulloblastoma Xenografts , 2006, Clinical Cancer Research.
[47] Yun-Fei Xia,et al. Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. , 2006, Cancer research.
[48] Angelo L. Vescovi,et al. Brain tumour stem cells , 2006, Nature Reviews Cancer.
[49] K. Asai,et al. Glia maturation factor‐β is produced by thymoma and may promote intratumoral T‐cell differentiation , 2005, Histopathology.
[50] S. Morrison,et al. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. , 2005, Genes & development.
[51] G. Glinsky,et al. Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. , 2005, The Journal of clinical investigation.
[52] Michael Dean,et al. Tumour stem cells and drug resistance , 2005, Nature Reviews Cancer.
[53] D. Farkas,et al. Isolation of cancer stem cells from adult glioblastoma multiforme , 2004, Oncogene.
[54] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[55] Ugo Orfanelli,et al. Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma , 2004, Cancer Research.
[56] M. Clarke,et al. Self-renewal and solid tumor stem cells , 2004, Oncogene.
[57] P. Dirks,et al. Cancer stem cells in nervous system tumors , 2004, Oncogene.
[58] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[59] M. Lohuizen,et al. Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas , 2004, Nature.
[60] C. Chow,et al. Phenylbutyrate and Phenylacetate Induce Differentiation and Inhibit Proliferation of Human Medulloblastoma Cells , 2004, Clinical Cancer Research.
[61] Sean J Morrison,et al. Bmi1, stem cells, and senescence regulation. , 2004, The Journal of clinical investigation.
[62] Michael F. Clarke,et al. Applying the principles of stem-cell biology to cancer , 2003, Nature Reviews Cancer.
[63] S. Morrison,et al. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation , 2003, Nature.
[64] Cynthia Hawkins,et al. Identification of a cancer stem cell in human brain tumors. , 2003, Cancer research.
[65] G. Sauvageau,et al. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells , 2003, Nature.
[66] Irving L. Weissman,et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells , 2003, Nature.
[67] S. Morrison,et al. Prospective identification of tumorigenic breast cancer cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[68] I. Weissman,et al. Stem cells, cancer, and cancer stem cells , 2001, Nature.
[69] H. Sasaki,et al. Expression of the antiapoptosis gene, AAC-11, as a prognosis marker in non-small cell lung cancer. , 2001, Lung cancer.
[70] C. Meijer,et al. Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. , 2001, Blood.
[71] I. Weissman,et al. Direct isolation of human central nervous system stem cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[72] K Kornfeld,et al. Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase. , 1999, Genes & development.
[73] A. Berns,et al. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. , 1999, Genes & development.
[74] B. Ross,et al. AAC-11, a novel cDNA that inhibits apoptosis after growth factor withdrawal. , 1997, Cancer research.
[75] Y. Haupt,et al. bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis. , 1993, Oncogene.
[76] W. Alexander,et al. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in Eμ-myc transgenic mice , 1991, Cell.
[77] S. Shamim,et al. Neurosurgery , 1985, Springer International Publishing.