The fungicide Tebuconazole induces electromechanical cardiotoxicity in murine heart and human cardiomyocytes derived from induced pluripotent stem cells.

[1]  J. Cruz,et al.  A novel substrate for arrhythmias in Chagas disease , 2021, PLoS neglected tropical diseases.

[2]  N. Sang,et al.  Tebuconazole induces liver injury coupled with ROS-mediated hepatic metabolism disorder. , 2021, Ecotoxicology and environmental safety.

[3]  Brendan R. Jackson,et al.  Trends in Agricultural Triazole Fungicide Use in the United States, 1992–2016 and Possible Implications for Antifungal-Resistant Fungi in Human Disease , 2021, Environmental health perspectives.

[4]  S. Abid-Essefi,et al.  Tebuconazole induced oxidative stress and histopathological alterations in adult rat heart. , 2020, Pesticide biochemistry and physiology.

[5]  C. Lemaire,et al.  Tebuconazole induces ROS-dependent cardiac cell toxicity by activating DNA damage and mitochondrial apoptotic pathway. , 2020, Ecotoxicology and environmental safety.

[6]  F. Neffati,et al.  Tebuconazole induced cardiotoxicity in male adult rat. , 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[7]  K. Masaki,et al.  Association Between Occupational Exposure to Pesticides and Cardiovascular Disease Incidence: The Kuakini Honolulu Heart Program , 2019, Journal of the American Heart Association.

[8]  Wenjun Gui,et al.  Endocrine disrupting effects of tebuconazole on different life stages of zebrafish (Danio rerio). , 2019, Environmental pollution.

[9]  A. Escobar,et al.  Phase 1 repolarization rate defines Ca2+ dynamics and contractility on intact mouse hearts , 2019, The Journal of general physiology.

[10]  Sabu Thomas,et al.  Toxic effects of the fungicide tebuconazole on the root system of fusarium-infected wheat plants. , 2018, Plant physiology and biochemistry : PPB.

[11]  S. Marcussi,et al.  Anxiety-associated behavior and genotoxicity found in adult Danio rerio exposed to tebuconazole-based commercial product. , 2018, Environmental toxicology and pharmacology.

[12]  Shing-Hwa Liu,et al.  Effects of tebuconazole on cytochrome P450 enzymes, oxidative stress, and endocrine disruption in male rats , 2018, Environmental toxicology.

[13]  Jing Liu,et al.  Triazole fungicide tebuconazole disrupts human placental trophoblast cell functions. , 2016, Journal of hazardous materials.

[14]  A. Green,et al.  An international database for pesticide risk assessments and management , 2016 .

[15]  F. Renaud,et al.  Pesticide pollution of multiple drinking water sources in the Mekong Delta, Vietnam: evidence from two provinces , 2015, Environmental Science and Pollution Research.

[16]  Bogdan Amuzescu,et al.  Action potential characterization of human induced pluripotent stem cell-derived cardiomyocytes using automated patch-clamp technology. , 2014, Assay and drug development technologies.

[17]  S. Fustinoni,et al.  Identification and quantification of metabolites of the fungicide tebuconazole in human urine. , 2014, Chemical research in toxicology.

[18]  S. Fustinoni,et al.  Biomonitoring human exposure to tebuconazole , 2012 .

[19]  Sean P. Palecek,et al.  Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling , 2012, Proceedings of the National Academy of Sciences.

[20]  O. Briand,et al.  Determination of farm workers' exposure to pesticides by hair analysis. , 2012, Toxicology letters.

[21]  James A Thomson,et al.  High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. , 2011, American journal of physiology. Heart and circulatory physiology.

[22]  A. Varró,et al.  Cardiac ventricular repolarization reserve: a principle for understanding drug‐related proarrhythmic risk , 2011, British journal of pharmacology.

[23]  M Coquery,et al.  Assessing pesticide concentrations and fluxes in the stream of a small vineyard catchment--effect of sampling frequency. , 2010, Environmental pollution.

[24]  V. Gouy,et al.  The periphyton as a multimetric bioindicator for assessing the impact of land use on rivers: an overview of the Ardières-Morcille experimental watershed (France) , 2010, Hydrobiologia.

[25]  T. Poiger,et al.  Azole fungicides: occurrence and fate in wastewater and surface waters. , 2008, Environmental science & technology.

[26]  D. Bers Calcium cycling and signaling in cardiac myocytes. , 2008, Annual review of physiology.

[27]  T. Shioya A simple technique for isolating healthy heart cells from mouse models. , 2007, The journal of physiological sciences : JPS.

[28]  Julie Boberg,et al.  Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[29]  D. Dix,et al.  Toxicogenomic study of triazole fungicides and perfluoroalkyl acids in rat livers predicts toxicity and categorizes chemicals based on mechanisms of toxicity. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[30]  Yun Shi,et al.  Selective solid-phase extraction of tebuconazole in biological and environmental samples using molecularly imprinted polymers , 2007, Analytical and bioanalytical chemistry.

[31]  A. Omelchenko,et al.  Frequency-dependent regulation of cardiac Na(+)/Ca(2+) exchanger. , 2005, American journal of physiology. Heart and circulatory physiology.

[32]  Leif Hove-Madsen,et al.  Atrial Fibrillation Is Associated With Increased Spontaneous Calcium Release From the Sarcoplasmic Reticulum in Human Atrial Myocytes , 2004, Circulation.

[33]  D. Bers Cardiac excitation–contraction coupling , 2002, Nature.

[34]  R. Smialowicz,et al.  The effects of perinatal tebuconazole exposure on adult neurological, immunological, and reproductive function in rats. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.

[35]  T. Poulos,et al.  Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[36]  P. Dorian,et al.  Rate dependence of the effect of antiarrhythmic drugs delaying cardiac repolarization: an overview. , 2000, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[37]  K. Bowen,et al.  Number of Tebuconazole Applications for Maximizing Disease Control and Yield of Peanut in Growers' Fields in Alabama. , 1997, Plant disease.

[38]  F. Tiaho,et al.  Regulation of the frequency‐dependent facilitation of L‐type Ca2+ currents in rat ventricular myocytes. , 1994, The Journal of physiology.

[39]  D. Noble,et al.  Ionic mechanisms of action potential prolongation at low temperature in guinea‐pig ventricular myocytes. , 1993, The Journal of physiology.

[40]  Yoshida Yuzo,et al.  Interaction of azole antifungal agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes. , 1987 .

[41]  T. Ternes,et al.  Water analysis: emerging contaminants and current issues. , 2007, Analytical chemistry.

[42]  R. Loeffler,et al.  The biochemical mode of action of some newer azole fungicides , 1993 .

[43]  K. Monyeki,et al.  Environmental Research and Public Health Exposure to Agrochemicals and Cardiovascular Disease: a Review , 2022 .