Spatio-temporal algorithms for processing laser speckle imaging data

The objective in many laser speckle imaging schemes is to relate the calculated laser speckle contrast to the object motion. In quantifying the laser speckle there are camps that advocate either the spatial or the temporal approach. Each has its merits. In this paper, we attempt to combine these two approaches to achieve a flexible, quantitative scheme. Additionally, we present some approaches that allow incorporation of prior knowledge of the subject motion. These algorithms are flexible and fast because they rely on vectorized processing. We demonstrate performance of these processing schemes on simulated and experimental speckle data.