Involvement of Jak2 tyrosine phosphorylation in Bcr–Abl transformation
暂无分享,去创建一个
Yan Wang | Matthew B. Wilson | Yan Wang | T. Smithgall | R. Arlinghaus | S. Xie | Tong Sun | Thomas E Smithgall | Shanhai Xie | Jiaxin Liu | T. Sun | Ralph B Arlinghaus | Jiaxin Liu | Matthew B Wilson
[1] Y. Wu,et al. Sequences within the first exon of BCR inhibit the activated tyrosine kinases of c-Abl and the Bcr-Abl oncoprotein. , 1996, Cancer research.
[2] J. Griffin,et al. STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells. , 2000, Blood.
[3] J. Darnell,et al. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. , 1994, Science.
[4] B. Calabretta,et al. Signal Transducer and Activator of Transcription (STAT)5 Activation by BCR/ABL Is Dependent on Intact Src Homology (SH)3 and SH2 Domains of BCR/ABL and Is Required for Leukemogenesis , 1999, The Journal of Experimental Medicine.
[5] Jürg Zimmermann,et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells , 1996, Nature Medicine.
[6] S. Goff,et al. Direct Interaction of Jak1 and v-Abl Is Required for v-Abl-Induced Activation of STATs and Proliferation , 1998, Molecular and Cellular Biology.
[7] Matthew B. Wilson,et al. Transformation of Myeloid Leukemia Cells to Cytokine Independence by Bcr-Abl Is Suppressed by Kinase-defective Hck* , 2000, The Journal of Biological Chemistry.
[8] I. Kerr,et al. Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop , 1997, Molecular and cellular biology.
[9] C. Sawyers. Chronic myeloid leukemia. , 1999, The New England journal of medicine.
[10] J. Marine,et al. Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors , 1998, Cell.
[11] A. Takaoka,et al. Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway. , 1998, Genes & development.
[12] N. Heisterkamp,et al. Tyrosine phosphorylation of CRKL in Philadelphia+ leukemia. , 1994, Blood.
[13] R. V. van Etten,et al. P210 and P190BCR/ABL Induce the Tyrosine Phosphorylation and DNA Binding Activity of Multiple Specific STAT Family Members* , 1996, The Journal of Biological Chemistry.
[14] G. B. Singh,et al. Antiinflammatory actions of Euphorbia splendens extract , 1997 .
[15] J. Wilson-Rawls,et al. P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation. , 1996, Cancer research.
[16] J. Dick,et al. Expression of bcr-abl abrogates factor-dependent growth of human hematopoietic M07E cells by an autocrine mechanism , 1994 .
[17] Charis Eng,et al. Catalytic specificity of protein-tyrosine kinases is critical for selective signalling , 1995, Nature.
[18] J. Griffin,et al. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl , 1996, The Journal of experimental medicine.
[19] E. Andreu,et al. Blockade of the Bcr-Abl Kinase Activity Induces Apoptosis of Chronic Myelogenous Leukemia Cells by Suppressing Signal Transducer and Activator of Transcription 5–Dependent Expression of Bcl-XL , 2000, The Journal of experimental medicine.
[20] F. Dong,et al. Tryptophan 650 of human granulocyte colony-stimulating factor (G-CSF) receptor, implicated in the activation of JAK2, is also required for G-CSF-mediated activation of signaling complexes of the p21ras route. , 1996, Blood.
[21] T Pawson,et al. Bcr‐Abl oncoproteins bind directly to activators of the Ras signalling pathway. , 1994, The EMBO journal.
[22] A. Yoshimura,et al. The Jak-Stat pathway in normal and perturbed hematopoiesis. , 2000, Blood.
[23] Nanxin Li,et al. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein , 1993, Cell.
[24] G. G. Stokes. "J." , 1890, The New Yale Book of Quotations.
[25] A. Cumano,et al. Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis , 1998, Cell.
[26] Yun Wu,et al. Bcr: a negative regulator of the Bcr-Abl oncoprotein , 1999, Oncogene.