IFPA 2005 Award in Placentology Lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? -- a review.

[1]  Thomas Jansson,et al.  Placental Phenotypes of Intrauterine Growth , 2005, Pediatric Research.

[2]  M. Hall,et al.  The expanding TOR signaling network. , 2005, Current opinion in cell biology.

[3]  B. Johansson,et al.  Hormonal regulation of glucose and system A amino acid transport in first trimester placental villous fragments. , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

[4]  T. Powell,et al.  Glucose transporter isoform 4 is expressed in the syncytiotrophoblast of first trimester human placenta. , 2005, Human reproduction.

[5]  T. Powell,et al.  Expression of placental mammalian target of rapamycin (mTOR) is altered in relation to fetal growth and mTOR regulates leucine transport , 2005 .

[6]  D. Brodsky,et al.  Current Concepts in Intrauterine Growth Restriction , 2004, Journal of intensive care medicine.

[7]  T. Powell,et al.  Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation. , 2004, American journal of physiology. Regulatory, integrative and comparative physiology.

[8]  T. Powell,et al.  Triglyceride hydrolase activities and expression of fatty acid binding proteins in the human placenta in pregnancies complicated by intrauterine growth restriction and diabetes. , 2004, The Journal of clinical endocrinology and metabolism.

[9]  J. Glazier,et al.  Nitric oxide and superoxide impair human placental amino acid uptake and increase Na+ permeability: implications for fetal growth. , 2004, Free radical biology & medicine.

[10]  L. Leach,et al.  Fine structure of the paracellular junctions of terminal villous capillaries in the perfused human placeta , 1992, Cell and Tissue Research.

[11]  J. Howell,et al.  A Novel Hypoxia-inducible Factor-independent Hypoxic Response Regulating Mammalian Target of Rapamycin and Its Targets* , 2003, Journal of Biological Chemistry.

[12]  T. Powell,et al.  Activity and protein expression of Na+/K+ ATPase are reduced in microvillous syncytiotrophoblast plasma membranes isolated from pregnancies complicated by intrauterine growth restriction. , 2003, The Journal of clinical endocrinology and metabolism.

[13]  T. Powell,et al.  ATP dependent Ca2+ transport across basal membrane of human syncytiotrophoblast in pregnancies complicated by intrauterine growth restriction or diabetes. , 2003, Placenta.

[14]  B. Johansson,et al.  Leptin stimulates the activity of the system A amino acid transporter in human placental villous fragments. , 2003, The Journal of clinical endocrinology and metabolism.

[15]  Wendy Dean,et al.  Regulation of supply and demand for maternal nutrients in mammals by imprinted genes , 2003, The Journal of physiology.

[16]  Michael N. Hall,et al.  TOR signalling in bugs, brain and brawn , 2003, Nature Reviews Molecular Cell Biology.

[17]  S. Smith,et al.  Hypoxia reduces expression and function of system A amino acid transporters in cultured term human trophoblasts. , 2003, American journal of physiology. Cell physiology.

[18]  C. Sibley,et al.  Activity and protein expression of the Na+/H+ exchanger is reduced in syncytiotrophoblast microvillous plasma membranes isolated from preterm intrauterine growth restriction pregnancies. , 2002, The Journal of clinical endocrinology and metabolism.

[19]  T. Powell,et al.  Parathyroid hormone-related peptide (38-94) amide stimulates ATP-dependent calcium transport in the Basal plasma membrane of the human syncytiotrophoblast. , 2002, The Journal of endocrinology.

[20]  G. Pardi,et al.  Intrauterine Growth Restriction Is Associated with Changes in Polyunsaturated Fatty Acid Fetal-Maternal Relationships , 2002, Pediatric Research.

[21]  T. Powell,et al.  Alterations in the activity of placental amino acid transporters in pregnancies complicated by diabetes. , 2002, Diabetes.

[22]  T. Powell,et al.  Na(+)/K(+)-ATPase activity and expression in syncytiotrophoblast plasma membranes in pregnancies complicated by diabetes. , 2002, Placenta.

[23]  T. Powell,et al.  Glucose transport and system A activity in syncytiotrophoblast microvillous and basal plasma membranes in intrauterine growth restriction. , 2002, Placenta.

[24]  C. Sibley,et al.  L-arginine transport by the microvillous plasma membrane of the syncytiotrophoblast from human placenta in relation to nitric oxide production: effects of gestation, preeclampsia, and intrauterine growth restriction. , 2002, The Journal of clinical endocrinology and metabolism.

[25]  T. N. Sugathan,et al.  Effect of insulin on transport kinetics of alpha‐aminoisobutyric acid in the perfused human placental lobule in vitro , 2001, Pediatrics international : official journal of the Japan Pediatric Society.

[26]  A. Jaeschke,et al.  Mammalian TOR: A Homeostatic ATP Sensor , 2001, Science.

[27]  G. Pardi,et al.  Placental transport of leucine, phenylalanine, glycine, and proline in intrauterine growth-restricted pregnancies. , 2001, The Journal of clinical endocrinology and metabolism.

[28]  T. Powell,et al.  Placental glucose transport in gestational diabetes mellitus. , 2001, American journal of obstetrics and gynecology.

[29]  R. Eastell,et al.  Intrauterine programming of adult body composition. , 2001, The Journal of clinical endocrinology and metabolism.

[30]  T. Powell,et al.  Placental nutrient transfer and fetal growth. , 2000, Nutrition.

[31]  B. Strandvik,et al.  Composition and permeability of syncytiotrophoblast plasma membranes in pregnancies complicated by intrauterine growth restriction. , 1999, Biochimica et biophysica acta.

[32]  F. Holsboer,et al.  Placental glucose transporter expression is regulated by glucocorticoids. , 1999, The Journal of clinical endocrinology and metabolism.

[33]  N. Illsley,et al.  Diabetes alters the expression and activity of the human placental GLUT1 glucose transporter. , 1999, The Journal of clinical endocrinology and metabolism.

[34]  T. Powell,et al.  Placental glucose transport and GLUT 1 expression in insulin-dependent diabetes. , 1999, American journal of obstetrics and gynecology.

[35]  T. Powell,et al.  Placental Transport of Leucine and Lysine Is Reduced in Intrauterine Growth Restriction1 , 1998, Pediatric Research.

[36]  T. Powell,et al.  Intrauterine Growth Restriction Is Associated with a Reduced Activity of Placental Taurine Transporters , 1998, Pediatric Research.

[37]  K. Leveno,et al.  Pregnancy Outcomes in Women With Gestational Diabetes Compared With the General Obstetric Population , 1997, Obstetrics and gynecology.

[38]  C. Sibley,et al.  Association between the Activity of the System A Amino Acid Transporter in the Microvillous Plasma Membrane of the Human Placenta and Severity of Fetal Compromise in Intrauterine Growth Restriction , 1997, Pediatric Research.

[39]  S. Ozanne,et al.  Fishing in the stream of diabetes: from measuring insulin to the control of fetal organogenesis. , 1996, Biochemical Society transactions.

[40]  P. Karl Insulin‐like growth factor‐1 stimulates amino acid uptake by the cultured human placental trophoblast , 1995, Journal of cellular physiology.

[41]  S. Gabbe,et al.  Insulin and glucose modulate glucose transporter messenger ribonucleic acid expression and glucose uptake in trophoblasts isolated from first-trimester chorionic villi. , 1995, American journal of obstetrics and gynecology.

[42]  C. Sibley,et al.  Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women. , 1994, The Journal of clinical investigation.

[43]  S. Gabbe,et al.  Insulinlike growth factors. Their regulation of glucose and amino acid transport in placental trophoblasts isolated from first-trimester chorionic villi. , 1994, The Journal of reproductive medicine.

[44]  B. Bax,et al.  Epidermal growth factor and insulin-like growth factor I differently influence the directional accumulation and transfer of 2-aminoisobutyrate (AIB) by human placental trophoblast in two-sided culture. , 1994, Biochemical and biophysical research communications.

[45]  T. Jansson,et al.  Glucose transporter protein expression in human placenta throughout gestation and in intrauterine growth retardation. , 1993, The Journal of clinical endocrinology and metabolism.

[46]  C. Sibley,et al.  Amino Acid (System A) Transporter Activity in Microvillous Membrane Vesicles from the Placentas of Appropriate and Small for Gestational Age Babies , 1993, Pediatric Research.

[47]  P. Gluckman,et al.  Fetal nutrition and cardiovascular disease in adult life , 1993, The Lancet.

[48]  B. Specker,et al.  Reduced serum osteocalcin and 1,25-dihydroxyvitamin D concentrations and low bone mineral content in small for gestational age infants: evidence of decreased bone formation rates. , 1993, The Journal of pediatrics.

[49]  P. Bennett,et al.  Diabetes and Obesity in the Offspring of Pima Indian Women With Diabetes During Pregnancy , 1993, Diabetes Care.

[50]  S. Fisher,et al.  Amino acid transport by the cultured human placental trophoblast: effect of insulin on AIB transport. , 1992, The American journal of physiology.

[51]  P. Bennett,et al.  Abnormal Glucose Tolerance During Pregnancy in Pima Indian Women: Long-Term Effects on Offspring , 1991, Diabetes.

[52]  D. Lajeunesse,et al.  Effect of insulin on d-glucose transport by human placental brush border membranes , 1990, Molecular and Cellular Endocrinology.

[53]  F. Stanley,et al.  Intrauterine growth and spastic cerebral palsy. I. Association with birth weight for gestational age. , 1990, American journal of obstetrics and gynecology.

[54]  G. Pardi,et al.  Umbilical amino acid concentrations in normal and growth-retarded fetuses sampled in utero by cordocentesis. , 1990, American journal of obstetrics and gynecology.

[55]  K. Nicolaides,et al.  Blood gases, pH, and lactate in appropriate- and small-for-gestational-age fetuses. , 1989, American journal of obstetrics and gynecology.

[56]  K. Nicolaides,et al.  Blood glucose and oxygen tension levels in small-for-gestational-age fetuses. , 1989, American journal of obstetrics and gynecology.

[57]  J. Challier,et al.  Effect of insulin on glucose uptake and metabolism in the human placenta. , 1986, The Journal of clinical endocrinology and metabolism.

[58]  J. Pedersen Weight and length at birth of infants of diabetic mothers. , 1954, Acta endocrinologica.