Mudmee silk and silk weaving are the long carried cultural wisdom heritages inherited from ancestors. Buriram is another province where weaves Thai silk especially in Na Pho district. Na Pho Silk Weaving Center (Na Pho Handicraft Center) has been known for madmee silk and silk weaving in quality, standardization and popular. It is retaining traditional patterns and colors. New patterns are created but not much and not very suitable to produce various products. There is an attempt to revamp image of silk fabric and mudmee silk to raise value and use of color in universal design. The development for silk fabric designing and coloring in Na Pho received support for standardization. The design patterns has been inspired by mudmee silk’s ancient patterns, Na Pho district, Buriram province. The highlight of ancient patterns including Lai Khom, Lai Tad, Lai Song Pool, Lai Khor, Lai Eid Tong, Lai Kra Tae Nang Tan or Lai Nak, Lai Kho Pai and Lai Kho Lo (Butterfly) are applied in the process of assigning weaves/colors, the size of the space and color placement for various patterns and application but it is still retaining the original pattern. Single color is applied for such patterns and become visible through its different including navy blue, blue and bluepurple. Study of variation results in color fastness to washing, color fastness to light, color fastness to water and color fastness to perspiration of silk fabric and mudmee silk showed after dyeing. Color fastness to washing exhibited very good wash fastness level