Systemic siRNA delivery via hydrodynamic intravascular injection.
暂无分享,去创建一个
[1] D. M. Carlson,et al. Gene expression following direct injection of DNA into liver. , 1994, Human gene therapy.
[2] F. Chisari,et al. High-level hepatitis B virus replication in transgenic mice , 1995, Journal of virology.
[3] S. Knechtle,et al. Naked DNA delivered intraportally expresses efficiently in hepatocytes. , 1996, Gene therapy.
[4] N. Armstrong,et al. Expression of naked plasmid DNA injected into the afferent and efferent vessels of rodent and dog livers. , 1997, Human gene therapy.
[5] A. Demetris,et al. Central venulitis in the allograft liver: a clinicopathologic study. , 1997, Transplantation.
[6] W. M. Lee,et al. Hepatitis B virus infection. , 1997, The New England journal of medicine.
[7] J. Wolff,et al. The efficient expression of intravascularly delivered DNA in rat muscle , 1998, Gene Therapy.
[8] J. Wolff,et al. High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. , 1999, Human gene therapy.
[9] B. Kennedy,et al. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. , 1999, Science.
[10] Dexi Liu,et al. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA , 1999, Gene Therapy.
[11] K. Zatloukal,et al. Mallory bodies revisited. , 2000, Journal of hepatology.
[12] J. Wolff,et al. Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor‐mediated process , 2000, The journal of gene medicine.
[13] G. Gores,et al. Apoptosis and liver disease. , 2000, The American journal of medicine.
[14] Young-Bum Kim,et al. Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice , 2000, Molecular and Cellular Biology.
[15] Martin Tabler,et al. Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila , 2001, Current Biology.
[16] M. Hashida,et al. Hepatic uptake and gene expression mechanisms following intravenous administration of plasmid DNA by conventional and hydrodynamics-based procedures. , 2001, The Journal of pharmacology and experimental therapeutics.
[17] J. Wolff,et al. Efficient expression of naked dna delivered intraarterially to limb muscles of nonhuman primates. , 2001, Human gene therapy.
[18] C. Morris,et al. Cell Surface Area Regulation and Membrane Tension , 2001, The Journal of Membrane Biology.
[19] U. Greber,et al. Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake , 2002, The Journal of cell biology.
[20] F. Chisari,et al. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[21] David L. Lewis,et al. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice , 2002, Nature Genetics.
[22] P. Williams,et al. Surgical procedures for intravascular delivery of plasmid DNA to organs. , 2002, Methods in enzymology.
[23] R. Pagano,et al. Role of deformation-induced lipid trafficking in the prevention of plasma membrane stress failure. , 2002, American journal of respiratory and critical care medicine.
[24] T. Starzl,et al. Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors. , 2002, Journal of hepatology.
[25] R. Schulte‐Hermann,et al. Cellular gene dose and kinetics of gene expression in mouse livers transfected by high-volume tail-vein injection of naked DNA. , 2002, DNA and cell biology.
[26] Douglas S. Conklin,et al. Gene expression: RNA interference in adult mice , 2002, Nature.
[27] Craig P. Hunter,et al. Systemic RNAi in C. elegans Requires the Putative Transmembrane Protein SID-1 , 2002, Science.
[28] R. Scheule,et al. Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA. , 2002, Human gene therapy.
[29] M. Manns,et al. Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA. , 2003, Gastroenterology.
[30] Hartmut Jaeschke,et al. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[31] Judy Lieberman,et al. RNA interference targeting Fas protects mice from fulminant hepatitis , 2003, Nature Medicine.
[32] P. Mcneil,et al. Plasma membrane disruption: repair, prevention, adaptation. , 2003, Annual review of cell and developmental biology.
[33] H. Giladi,et al. Small interfering RNA inhibits hepatitis B virus replication in mice. , 2003, Molecular therapy : the journal of the American Society of Gene Therapy.
[34] N. Selzner,et al. Protective strategies against ischemic injury of the liver. , 2003, Gastroenterology.
[35] R. Wattiaux,et al. Uptake by mouse liver and intracellular fate of plasmid DNA after a rapid tail vein injection of a small or a large volume , 2003, The journal of gene medicine.
[36] M. Manns,et al. Caspase 8 small interfering RNA prevents acute liver failure in mice , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[37] E. H. Feinberg,et al. Transport of dsRNA into Cells by the Transmembrane Protein SID-1 , 2003, Science.
[38] R. Wattiaux,et al. Hydrodynamics‐based transfection of the liver: entrance into hepatocytes of DNA that causes expression takes place very early after injection , 2004 .
[39] J. Lieberman,et al. Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[40] D. Lewis,et al. A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.
[41] Y. Takakura,et al. Hydrodynamics‐based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery , 2004, The journal of gene medicine.
[42] D. Ganem,et al. Hepatitis B virus infection--natural history and clinical consequences. , 2004, The New England journal of medicine.
[43] Y. Takakura,et al. Hepatic delivery of particulates in the submicron range by a hydrodynamics‐based procedure: implications for particulate gene delivery systems , 2004, The journal of gene medicine.
[44] U. Kutay,et al. Nuclear Export of MicroRNA Precursors , 2004, Science.
[45] Matthias John,et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs , 2004, Nature.
[46] T. Tumpey,et al. Protection against lethal influenza virus challenge by RNA interference in vivo. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[47] Anton P. McCaffrey,et al. In vivo activity of nuclease-resistant siRNAs. , 2004, RNA.
[48] S. Margulies,et al. Plasma membrane surface increases with tonic stretch of alveolar epithelial cells. , 2004, American journal of respiratory cell and molecular biology.
[49] Mark E. Davis,et al. Lack of interferon response in animals to naked siRNAs , 2004, Nature Biotechnology.
[50] D. Stolz,et al. Hydroporation as the mechanism of hydrodynamic delivery , 2004, Gene Therapy.
[51] J. Contreras,et al. Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice. , 2004 .
[52] T. Kirchhausen,et al. An emergency response team for membrane repair , 2005, Nature Reviews Molecular Cell Biology.
[53] S. Ashley,et al. RNA interference: a mammalian SID-1 homologue enhances siRNA uptake and gene silencing efficacy in human cells. , 2005, Biochemical and biophysical research communications.
[54] K. Naruse,et al. Stretch-induced cell proliferation is mediated by FAK-MAPK pathway. , 2005, Life sciences.
[55] S. P. Bradley,et al. Gene Silencing in the Endocrine Pancreas Mediated by Short-Interfering RNA , 2005, Pancreas.
[56] B. Polisky,et al. Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication , 2005, Hepatology.
[57] J. Calvete,et al. Hydrodynamic liver gene transfer mechanism involves transient sinusoidal blood stasis and massive hepatocyte endocytic vesicles , 2005, Gene Therapy.
[58] S. Matecki,et al. Optimization of regional intraarterial naked DNA-mediated transgene delivery to skeletal muscles in a large animal model. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[59] Keith Bowman,et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs , 2005, Nature Biotechnology.
[60] Weida Huang,et al. Reduction of PTP1B by RNAi upregulates the activity of insulin controlled fatty acid synthase promoter. , 2005, Biochemical and biophysical research communications.
[61] J. Wolff,et al. The mechanism of naked DNA uptake and expression. , 2005, Advances in genetics.
[62] R. Scheule,et al. Transient siRNA-mediated attenuation of liver expression from an alpha-galactosidase A plasmid reduces subsequent humoral immune responses to the transgene product in mice. , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.
[63] Mark E. Davis,et al. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging , 2006, Nucleic acids research.
[64] J. Wolff,et al. Mechanism of plasmid delivery by hydrodynamic tail vein injection. II. Morphological studies , 2006, The journal of gene medicine.
[65] C. Echeverri,et al. In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5 , 2006, Nucleic acids research.
[66] D. Lewis,et al. Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules , 2006, The journal of gene medicine.
[67] G. Gores,et al. Apoptosis and necrosis in the liver: A tale of two deaths? , 2006, Hepatology.
[68] Yudong D. He,et al. Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice , 2006, Nucleic acids research.