Depression During Pregnancy.

Introduction : Depression during pregnancy seems to be dominated by the postpartum depression. It is important to remember about this condition and its symptoms as they are easy to be mistaken with mood changes and other behavioural changes common during pregnancy. Although we know the risk factors for this condition, we still do not know its complex etiology. Moreover, there is also not enough information about the treatment. The aim of the study : The purpose of this systemic review was to collect and analyse causes and possibilities of treatment depression during pregnancy. Material and method : Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords:

[1]  D. Degmečić,et al.  Depression and Suicidality during Pregnancy. , 2018, Psychiatria Danubina.

[2]  Etienne Sibille,et al.  Somatostatin-Positive Gamma-Aminobutyric Acid Interneuron Deficits in Depression: Cortical Microcircuit and Therapeutic Perspectives , 2017, Biological Psychiatry.

[3]  C. Andrade.  Antidepressant Exposure During Pregnancy and Risk of Autism in the Offspring, 1: Meta-Review of Meta-Analyses. , 2017, The Journal of clinical psychiatry.

[4]  Brian K. Lee,et al.  Antidepressants during pregnancy and autism in offspring: population based cohort study , 2017, British Medical Journal.

[5]  K. Howdeshell,et al.  Depression and Its Treatment During Pregnancy: Overview and Highlights , 2017, Birth defects research.

[6]  G. Koren,et al.  Selective Serotonin Reuptake Inhibitors during Pregnancy: Do We Have Now More Definite Answers Related to Prenatal Exposure? , 2017, Birth defects research.

[7]  O. Bosch.  Look behind the eyes – vasopressin rules the day , 2017, The Journal of physiology.

[8]  Allison C. Nugent,et al.  Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine , 2017, Biological Psychiatry.

[9]  L. Forsberg,et al.  Neonatal Morbidity After Maternal Use of Antidepressant Drugs During Pregnancy , 2016, Pediatrics.

[10]  I. Mancilla-Herrera,et al.  The Immune System and the Role of Inflammation in Perinatal Depression , 2016, Neuroscience Bulletin.

[11]  R. Langan,et al.  Identification and Management of Peripartum Depression. , 2016, American family physician.

[12]  A. Pathak,et al.  Postpartum psychiatric disorders: Early diagnosis and management , 2015, Indian journal of psychiatry.

[13]  R. Cui,et al.  The Effects of Psychological Stress on Depression , 2015, Current neuropharmacology.

[14]  S. Hernández-Díaz,et al.  Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn. , 2015, JAMA.

[15]  E. Garne,et al.  Selective serotonin reuptake inhibitor prescribing before, during and after pregnancy: a population‐based study in six European regions , 2015, BJOG : an international journal of obstetrics and gynaecology.

[16]  M. López‐Martínez,et al.  Hypothalamic-pituitary-adrenal axis function during perinatal depression , 2015, Neuroscience Bulletin.

[17]  I. Hertz-Picciotto,et al.  Prenatal SSRI Use and Offspring With Autism Spectrum Disorder or Developmental Delay , 2014, Pediatrics.

[18]  M. Maes,et al.  So depression is an inflammatory disease, but where does the inflammation come from? , 2013, BMC Medicine.

[19]  I. Soldatovic,et al.  Frequency of perinatal depression in Serbia and associated risk factors , 2013, The International journal of social psychiatry.

[20]  P. Blier,et al.  Serotonin and beyond: therapeutics for major depression , 2013, Philosophical Transactions of the Royal Society B: Biological Sciences.

[21]  J. West,et al.  Live and Non-Live Pregnancy Outcomes among Women with Depression and Anxiety: A Population-Based Study , 2012, PloS one.

[22]  R. Ho,et al.  Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: a meta-analysis and meta-regression. , 2012, Journal of affective disorders.

[23]  E. Palazidou.  The neurobiology of depression. , 2012, British medical bulletin.

[24]  M. Kaster,et al.  Depressive-like behavior induced by tumor necrosis factor-α in mice , 2012, Neuropharmacology.

[25]  K. Hashimoto.  The role of glutamate on the action of antidepressants , 2011, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[26]  L. Kooistra,et al.  Validation of the Edinburgh Depression Scale during pregnancy. , 2011, Journal of psychosomatic research.

[27]  Satish Iyengar,et al.  A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. , 2010, Archives of general psychiatry.

[28]  G. Mor,et al.  REVIEW ARTICLE: The Immune System in Pregnancy: A Unique Complexity , 2010, American journal of reproductive immunology.

[29]  P. Gaspar,et al.  New perspectives on the neurodevelopmental effects of SSRIs. , 2010, Trends in pharmacological sciences.

[30]  J. Korf,et al.  The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[31]  D. Stewart,et al.  The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists. , 2009, General hospital psychiatry.

[32]  Megan V. Smith,et al.  Typical somatic symptoms of pregnancy and their impact on a diagnosis of major depressive disorder. , 2009, General hospital psychiatry.

[33]  J. Koo,et al.  Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. , 2009, Current opinion in investigational drugs.

[34]  P. Levitt,et al.  Prenatal exposure to drugs: effects on brain development and implications for policy and education , 2009, Nature Reviews Neuroscience.

[35]  V. Pop,et al.  Depressive disorder and thyroid axis functioning during pregnancy , 2009, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[36]  Stafford L. Lightman,et al.  The HPA axis in major depression: classical theories and new developments , 2008, Trends in Neurosciences.

[37]  Mark Olfson,et al.  Psychiatric disorders in pregnant and postpartum women in the United States. , 2008, Archives of general psychiatry.

[38]  J. Koo,et al.  IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress , 2008, Proceedings of the National Academy of Sciences.

[39]  T. Einarson,et al.  Paroxetine and congenital malformations: meta-Analysis and consideration of potential confounding factors. , 2007, Clinical therapeutics.

[40]  H. Sørensen,et al.  Maternal Use of Selective Serotonin Reuptake Inhibitors and Risk of Congenital Malformations , 2006, Epidemiology.

[41]  J. Trowsdale,et al.  Mother's little helpers: mechanisms of maternal-fetal tolerance , 2006, Nature Immunology.

[42]  Eric J. Nestler,et al.  New approaches to antidepressant drug discovery: beyond monoamines , 2006, Nature Reviews Neuroscience.

[43]  F. Holsboer,et al.  Listening to mutant mice: a spotlight on the role of CRF/CRF receptor systems in affective disorders , 2005, Neuroscience & Biobehavioral Reviews.

[44]  C. Lyketsos,et al.  Mood Disorders in the Medically Ill: Scientific Review and Recommendations , 2005, Biological Psychiatry.

[45]  J. D. den Boer,et al.  Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates. , 2004, Journal of the American Academy of Child and Adolescent Psychiatry.

[46]  C. Henshaw.  Mood disturbance in the early puerperium: a review , 2003, Archives of Women’s Mental Health.

[47]  M. Heineman,et al.  The immunology of successful pregnancy. , 2003, Human reproduction update.

[48]  V. Klimek,et al.  Elevated Concentrations of CRF in the Locus Coeruleus of Depressed Subjects , 2003, Neuropsychopharmacology.

[49]  J. Endicott,et al.  Controlled clinical trial of interpersonal psychotherapy versus parenting education program for depressed pregnant women. , 2003, The American journal of psychiatry.

[50]  S. Oke,et al.  Cohort study of depressed mood during pregnancy and after childbirth , 2001, BMJ : British Medical Journal.

[51]  R. Newcombe,et al.  Association between postpartum thyroid dysfunction and thyroid antibodies and depression. , 1992, BMJ.

[52]  Goran Arbanas.  Diagnostic and Statistical Manual of Mental Disorders (DSM-5) , 2015 .

[53]  H. Flynn,et al.  Risk factors for depressive symptoms during pregnancy: a systematic review. , 2010, American journal of obstetrics and gynecology.

[54]  T. Field,et al.  Prenatal depression restricts fetal growth. , 2009, Early human development.

[55]  D. Stewart,et al.  The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists. , 2009, Obstetrics and gynecology.

[56]  ACOG Committee Opinion No. 343: psychosocial risk factors: perinatal screening and intervention. , 2006, Obstetrics and gynecology.

[57]  J. Lauder,et al.  Roles for serotonin in neuroembryogenesis. , 1981, Advances in experimental medicine and biology.