Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

[1]  R. Finnell,et al.  Craniosynostosis: current conceptions and misconceptions , 2016, AIMS Genetics.

[2]  Rosa Bartolomeo,et al.  FGF signalling regulates bone growth through autophagy , 2015, Nature.

[3]  G. Carle,et al.  Autophagy in bone: Self-eating to stay in balance , 2015, Ageing Research Reviews.

[4]  R. Shiang,et al.  Gene Expression Changes Between Patent and Fused Cranial Sutures in a Nonsyndromic Craniosynostosis Population , 2015, Eplasty.

[5]  Yu Fu,et al.  Roles of SATB2 in Site‐Specific Stemness, Autophagy and Senescence of Bone Marrow Mesenchymal Stem Cells , 2015, Journal of cellular physiology.

[6]  L. Griffith,et al.  Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation , 2014, Stem Cell Research & Therapy.

[7]  S. Kang,et al.  Beclin‐1 Is Required for RANKL‐Induced Osteoclast Differentiation , 2014, Journal of cellular physiology.

[8]  D. Dempster,et al.  Autophagy in osteoblasts is involved in mineralization and bone homeostasis , 2014, Autophagy.

[9]  Chunjuan Song,et al.  Autophagy induction is a survival response against oxidative stress in bone marrow-derived mesenchymal stromal cells. , 2014, Cytotherapy.

[10]  M. Barba,et al.  Molecular and functional characterization of calvarial stem cells in nonsyndromic craniosynostosis: role of the primary cilium-related signaling in the abnormal osteogenic niche , 2014 .

[11]  J. Aubin,et al.  The R740S mutation in the V‐ATPase a3 subunit results in osteoclast apoptosis and defective early‐stage autophagy , 2013, Journal of cellular biochemistry.

[12]  Wei Wang,et al.  The dual role of autophagy in chondrocyte responses in the pathogenesis of articular cartilage degeneration in osteoarthritis. , 2013, International journal of molecular medicine.

[13]  Ying-ying Jing,et al.  Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells , 2013, Cell Death and Disease.

[14]  M. Selig,et al.  Suppression of Autophagy in Osteocytes Mimics Skeletal Aging* , 2013, The Journal of Biological Chemistry.

[15]  M. Barba,et al.  Gene expression profiling in human craniosynostoses: a tool to investigate the molecular basis of suture ossification , 2012, Child's Nervous System.

[16]  M. Barba,et al.  Genetic basis of single-suture synostoses: genes, chromosomes and clinical implications , 2012, Child's Nervous System.

[17]  Seung-Yong Yoon,et al.  Microtubule-associated protein light chain 3 regulates Cdc42-dependent actin ring formation in osteoclast. , 2012, The international journal of biochemistry & cell biology.

[18]  H. Virgin,et al.  Autophagy proteins regulate the secretory component of osteoclastic bone resorption. , 2011, Developmental cell.

[19]  C. Senders,et al.  Differential Growth Factor Adsorption to Calvarial Osteoblast-Secreted Extracellular Matrices Instructs Osteoblastic Behavior , 2011, PloS one.

[20]  M. Rieder,et al.  IGF1R variants associated with isolated single suture craniosynostosis , 2011, American journal of medical genetics. Part A.

[21]  Francesca Antonacci,et al.  Copy Number Variation Analysis in Single-Suture Craniosynostosis: Multiple Rare Variants Including RUNX2 Duplication in Two Cousins With Metopic Craniosynostosis , 2010, American journal of medical genetics. Part A.

[22]  M. Lotz,et al.  Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. , 2010, Arthritis and rheumatism.

[23]  R. Layfield,et al.  Recent advances in understanding the molecular basis of Paget disease of bone , 2009, Journal of Clinical Pathology.

[24]  A. Wilkie,et al.  Scalp fibroblasts have a shared expression profile in monogenic craniosynostosis , 2009, Journal of Medical Genetics.

[25]  C. P. Morris,et al.  Identification of genes differentially expressed by prematurely fused human sutures using a novel in vivo - in vitro approach. , 2008, Differentiation; research in biological diversity.

[26]  A. Parfitt,et al.  Perspective: Quantifying Osteoblast and Osteocyte Apoptosis: Challenges and Rewards , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  J. McCarthy,et al.  Immunolocalization of transforming growth factor beta 1, beta 2, and beta 3 and insulin-like growth factor I in premature cranial suture fusion. , 1997, Plastic and reconstructive surgery.

[28]  L. Harhaji-Trajković,et al.  Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells. , 2013, Bone.

[29]  M. Barba,et al.  Lim mineralization protein is involved in the premature calvarial ossification in sporadic craniosynostoses. , 2013, Bone.

[30]  M. Passos-Bueno,et al.  Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations. , 2008, Frontiers of oral biology.