Antibacterial activity of cinnamon ethanol extract (cinnamomum burmannii) and its application as a mouthwash to inhibit streptococcus growth

Cinnamon bark has been commonly used as spicy and traditional medicine. It contains several antibacterial compounds such as flavonoids, saponins, and cinnamaldehyde. Several studies have been done to know the antibacterial effect on bacteria such as Streptococcus in vitro. This study aimed to examine the antibacterial activity of cinnamon ethanol extract against Streptococcus and its application as mouthwash to inhibit the bacteria. The cinnamon bark was macerated followed by extracted in 80% ethanol. Bacterial samples were isolated from dental plaque of patients visiting dental clinic drg. Syahdiana Waty in Medan, North Sumatra. The isolates were identified using Vitek 2 compact. Secondary metabolites were detected using previously described method. Antibacterial assay was done at extract concentration of 6.25%, 12.5%, and 25%. The result showed that alkaloids, flavonoids, saponins, and glycoside were detected in the extract. Nine bacterial species were identified as Streptococcus mitis, S. sanguinis, S. salivarius, S. pluranimalium, S. pneumoniae, S. alactolyticus, Kocuria rosea, Kocuria kristinae, and Spingomonas paucimolis. It showed that the extract of Cinnamon bark significantly inhibited Streptococcus growth, and it was effective as mouthwash.

[1]  B. Nagoba,et al.  Rare and unusual isolates of viridans streptococci from the human oral cavity , 2016, Indian journal of pathology & microbiology.

[2]  N. Kasuma,et al.  PENGARUH BERKUMUR DENGAN LARUTAN EKSTRAK SIWAK (Salvadora persica) TERHADAP pH SALIVA RONGGA MULUT , 2015 .

[3]  A. Dziedzic,et al.  Inhibition of Oral Streptococci Growth Induced by the Complementary Action of Berberine Chloride and Antibacterial Compounds , 2015, Molecules.

[4]  Hussein,et al.  Microbial Biofilm Formation as a Dental-fouling Microorganisms Attachment Phenomenon in Oral Cavity Environment , 2015 .

[5]  Diah Septia Liantari EFFECT OF WULUH STARFRUIT LEAF EXTRACT FOR Streptococcus mutans GROWTH , 2014 .

[6]  Rr. Sarah Ladytama,et al.  EFEKTIVITAS LARUTAN EKSTRAK JERUK NIPIS (Citrus Aurantifolia) SEBAGAI OBAT KUMUR TERHADAP PENURUNAN INDEKS PLAK PADA REMAJA USIA 12 - 15 TAHUN - Studi di SMP Nurul Islami, Mijen, Semarang , 2014 .

[7]  Anggri Puspita Pengaruh Konsentrasi Ekstrak Kayu Manis (Cinnamomumburmanni) dalam Menurunkan Pertumbuhan Streptococcus Mutans Secara In Vitro , 2014 .

[8]  N. Tripathi,et al.  Antibacterial properties of cinnamon stick oil with special reference to Streptococcus pyogenes and Pseudomonas aeruginosa , 2014 .

[9]  R. A. Al-Naggar,et al.  Antimicrobial Activity of Aqueous Extracts of Cinnamon and Ginger on Two Oral Pathogens Causing Dental Caries , 2013 .

[10]  M. Taher,et al.  Antimicrobial Activity and Synergic Effect of Cinnamomum burmannii's Essential Oil & its isolated compound (Cinnamaldehyde) , 2013 .

[11]  Dhruw Chandrabhan,et al.  Isolation of Dental Caries Bacteria from Dental Plaque and Effect of Tooth Pastes on Acidogenic Bacteria , 2012 .

[12]  M. Bouzari,et al.  Identification of Streptococcus salivarius bacteriophage isolated from Persian Gulf as a potential agent for dental caries phage therapy , 2010 .

[13]  W. Yam,et al.  Kocuria kristinae infection associated with acute cholecystitis , 2005, BMC infectious diseases.

[14]  drg.M.Kes Rini Pratiwi PERBEDAAAN DAYA HAMBAT TERHADAP STREPTOCOCCUS MUTANS DARI BEBERAPA PASTA GIGI YANG MENGANDUNG HERBAL , 2005 .

[15]  R. Pratiwi The difference of inhibition zones toward Streptococcus mutans among several herbal toothpaste , 2005 .