Identifying higher‐volume antibiotic outpatient prescribers using publicly available medicare part D data — United States, 2019

Antibiotic prescribing can lead to adverse drug events and antibiotic resistance, which pose ongoing urgent public health threats. 1 Adults aged ≥65 years (older adults) are recipients of the highest rates of outpatient antibiotic prescribing and are at increased risk for antibiotic- related adverse events, including Clostridioides diffi-cile and antibiotic- resistant infections and related deaths. 1 Variation in antibiotic prescribing quality is primarily driven by prescribing pat-terns of individual health care providers, independent of patients’ underlying comorbidities and diagnoses. 2 Engaging higher- volume prescribers (the top 10% of prescribers by antibiotic volume) in an tibiotic stewardship interventions, such as peer comparison audit and feedback in which health care providers receive data on their prescribing performance compared with that of other health care providers, has been effective in reducing antibiotic prescribing in outpatient settings and can be implemented on a large scale. 3- 5 This study analyzed data from the Centers for Medicare & Medicaid Services (CMS) Part D Prescriber Public Use Files (PUFs)* to describe higher- volume antibiotic prescribers in outpatient settings compared with lower- volume prescribers (the lower 90% of prescribers by antibiotic volume). Among the 59.4 million

[1]  J. Grimshaw,et al.  Effect of Antibiotic-Prescribing Feedback to High-Volume Primary Care Physicians on Number of Antibiotic Prescriptions: A Randomized Clinical Trial. , 2021, JAMA internal medicine.

[2]  K. Tu,et al.  The Association between High and Unnecessary Antibiotic Prescribing: A Cohort Study Using Family Physician Electronic Medical Records. , 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  M. Kainer,et al.  Analysis of a high-prescribing state’s 2016 outpatient antibiotic prescriptions: Implications for outpatient antimicrobial stewardship interventions , 2019, Infection Control & Hospital Epidemiology.

[4]  Antibiotic resistance threats in the United States, 2019 , 2019 .

[5]  D. Lisi Outpatient Antibiotic Prescribing for Older Adults in the United States: 2011 to 2014 , 2019, Journal of the American Geriatrics Society.

[6]  L. Hicks,et al.  Advances in optimizing the prescription of antibiotics in outpatient settings , 2018, British Medical Journal.

[7]  N. Stone,et al.  Outpatient Antibiotic Prescribing Among Older Adults in the United States, 2011 to 2014 , 2017, Journal of the American Geriatrics Society.

[8]  F. Greaves,et al.  Provision of social norm feedback to high prescribers of antibiotics in general practice: a pragmatic national randomised controlled trial , 2016, The Lancet.

[9]  T. Greene,et al.  Variation in Outpatient Antibiotic Prescribing for Acute Respiratory Infections in the Veteran Population , 2015, Annals of Internal Medicine.

[10]  S. Schrag,et al.  US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  Yuting Zhang,et al.  Geographic variation in outpatient antibiotic prescribing among older adults. , 2012, Archives of internal medicine.