Expression of hypoxia inducible factor‐1α during liver regeneration induced by partial hepatectomy in rats

Abstract: Background/Aims: It has been well established that hypoxia inducible factor‐1α (HIF‐1α) transcribes essential factors in cell preservation, including angiogenesis, during hypoxia. However, the transition of HIF‐1α expression during liver regeneration remains unknown. In this study, a role of HIF‐1α was experimentally elucidated in relation to sinusoidal endothelial reconstruction during liver regeneration.

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