A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation.

[1]  G. Xiao,et al.  The basic helix loop helix transcription factor twist1 is a novel regulator of ATF4 in osteoblasts , 2012, Journal of cellular biochemistry.

[2]  Tao He,et al.  Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms , 2011, Cell Research.

[3]  V. Rotter,et al.  Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells , 2011, Cell Death and Differentiation.

[4]  David M. Thomas,et al.  Comprehensive Mapping of p53 Pathway Alterations Reveals an Apparent Role for Both SNP309 and MDM2 Amplification in Sarcomagenesis , 2010, Clinical Cancer Research.

[5]  D. Bar-Sagi,et al.  Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells. , 2010, Cancer cell.

[6]  Chi-Hung Huang,et al.  Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition , 2010, Nature Cell Biology.

[7]  C. Glackin,et al.  Twist‐ing cell fate: Mechanistic insights into the role of twist in lineage specification/differentiation and tumorigenesis , 2010, Journal of cellular biochemistry.

[8]  E. Olson,et al.  Homozygous nonsense mutations in TWIST2 cause Setleis syndrome. , 2010, American journal of human genetics.

[9]  J. Manfredi The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. , 2010, Genes & development.

[10]  C. Prives,et al.  The C-terminus of p53 binds the N-terminal domain of MDM2 , 2010, Nature Structural &Molecular Biology.

[11]  B. Hemmings,et al.  PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage , 2010, Oncogene.

[12]  D. Meek,et al.  Phosphorylation of serine 392 in p53 is a common and integral event during p53 induction by diverse stimuli. , 2010, Cellular signalling.

[13]  J. Coindre,et al.  Well-differentiated and dedifferentiated liposarcomas , 2010, Virchows Archiv.

[14]  F. Vesuna,et al.  Twist modulates breast cancer stem cells by transcriptional regulation of CD24 expression. , 2009, Neoplasia.

[15]  Yu Qin,et al.  Metastasis-induction and apoptosis-protection by TWIST in gastric cancer cells , 2009, Clinical & Experimental Metastasis.

[16]  C. Glackin,et al.  TWIST Family of Basic Helix‐Loop‐Helix Transcription Factors Mediate Human Mesenchymal Stem Cell Growth and Commitment , 2009, Stem cells.

[17]  Kevin Karplus,et al.  SAM-T08, HMM-based protein structure prediction , 2009, Nucleic Acids Res..

[18]  Wen-juan Wang,et al.  Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells , 2009, Clinical Cancer Research.

[19]  A. Firulli,et al.  A twist of insight - the role of Twist-family bHLH factors in development. , 2009, The International journal of developmental biology.

[20]  H. Izumi,et al.  Twist and p53 reciprocally regulate target genes via direct interaction , 2008, Oncogene.

[21]  C. Sander,et al.  Functional Copy-Number Alterations in Cancer , 2008, PloS one.

[22]  R. Maestro,et al.  Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. , 2008, Cancer cell.

[23]  Y. Wong,et al.  Role of p14ARF in TWIST-mediated senescence in prostate epithelial cells. , 2007, Carcinogenesis.

[24]  Stephen R Comeau,et al.  ClusPro: Performance in CAPRI rounds 6–11 and the new server , 2007, Proteins.

[25]  Aaron Bensimon,et al.  Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication , 2006, Nature.

[26]  R. Maestro,et al.  Twist is substrate for caspase cleavage and proteasome-mediated degradation , 2006, Cell Death and Differentiation.

[27]  T. Jacks,et al.  Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas. , 2005, Cancer research.

[28]  V. Raman,et al.  HOXA5-Twist Interaction Alters p53 Homeostasis in Breast Cancer Cells* , 2005, Journal of Biological Chemistry.

[29]  A. Puisieux,et al.  Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells. , 2004, Cancer cell.

[30]  D. Tuveson,et al.  Twist induces an epithelial-mesenchymal transition to facilitate tumor metastasis , 2004, Cancer biology & therapy.

[31]  T. Jacks,et al.  Increased Sensitivity to UV Radiation in Mice with a p53 Point Mutation at Ser389 , 2004, Molecular and Cellular Biology.

[32]  Xin Lu,et al.  Ser392 Phosphorylation Regulates the Oncogenic Function of Mutant p53 , 2004, Cancer Research.

[33]  S. Ramaswamy,et al.  Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis , 2004, Cell.

[34]  M. Justice,et al.  A twist code determines the onset of osteoblast differentiation. , 2004, Developmental cell.

[35]  C. Fletcher,et al.  Lipomatous tumours of soft tissues: an update , 2004, Virchows Archiv.

[36]  B. Gusterson,et al.  Ser 392 Phosphorylation Regulates the Oncogenic Function of Mutant p 53 , 2004 .

[37]  P. Meltzer,et al.  Mechanisms of sarcoma development , 2003, Nature Reviews Cancer.

[38]  P. Meltzer,et al.  Soft tissue sarcomas of adults: state of the translational science. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[39]  Yang Xu,et al.  Regulation of p53 responses by post-translational modifications , 2003, Cell Death and Differentiation.

[40]  E. Olson,et al.  Twist Regulates Cytokine Gene Expression through a Negative Feedback Loop that Represses NF-κB Activity , 2003, Cell.

[41]  G. Hannon,et al.  Transformation of normal human cells in the absence of telomerase activation. , 2002, Cancer cell.

[42]  M. Baylies,et al.  A Twist in fate: evolutionary comparison of Twist structure and function. , 2002, Gene.

[43]  F. Mertens,et al.  World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone , 2002 .

[44]  S. Knuutila,et al.  DNA copy number amplifications in sarcomas with homogeneously staining regions and double minutes. , 2001, Cytometry.

[45]  M. Kapoor,et al.  Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation , 2000, Oncogene.

[46]  L. Kedes,et al.  Twist is a potential oncogene that inhibits apoptosis. , 1999, Genes & development.

[47]  L. Kedes,et al.  Regulation of Histone Acetyltransferases p300 and PCAF by the bHLH Protein Twist and Adenoviral Oncoprotein E1A , 1999, Cell.

[48]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[49]  Yoichi Taya,et al.  DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2 , 1997, Cell.

[50]  H. Sakamoto,et al.  Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53. , 1997, Biochemistry.

[51]  M. Birrer,et al.  Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas. , 1997, Gynecologic oncology.

[52]  A. D. Dei Tos,et al.  Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma. , 1997, The Journal of pathology.

[53]  A. Levine,et al.  Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain , 1996, Science.

[54]  A. Lassar,et al.  Inhibition of Myogenic bHLH and MEF2 Transcription Factors by the bHLH Protein Twist , 1996, Science.

[55]  A. D. Dei Tos,et al.  Tumor suppressor genes and related molecules in leiomyosarcoma. , 1996, The American journal of pathology.

[56]  P. Jeffrey,et al.  Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. , 1994, Science.

[57]  A. Levine,et al.  Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. , 1994, Genes & development.

[58]  A. Levine,et al.  Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. , 1994, Cancer research.

[59]  D. Housman,et al.  p53-dependent apoptosis modulates the cytotoxicity of anticancer agents , 1993, Cell.

[60]  D. Lane,et al.  Regulation of the specific DNA binding function of p53 , 1992, Cell.