Computational protein engineering
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[1] W. DeGrado,et al. Protein Design: A Hierarchic Approach , 1995, Science.
[2] E. Corey,et al. On the failure of de novo-designed peptides as biocatalysts. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[3] J R Desjarlais,et al. De novo design of the hydrophobic cores of proteins , 1995, Protein science : a publication of the Protein Society.
[4] R. Sauer,et al. An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of lambda repressor. , 1986, Biochemistry.
[5] W. Rastetter. Enzyme engineering: applications and promise , 1983 .
[6] C. Pabo. Molecular technology: Designing proteins and peptides , 1983, Nature.
[7] H. Wilks,et al. Alteration of enzyme specificity and catalysis by protein engineering. , 1991, Current opinion in biotechnology.
[8] S. L. Mayo,et al. Probing the role of packing specificity in protein design. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[9] H W Hellinga,et al. Construction of a family of Cys2His2 zinc binding sites in the hydrophobic core of thioredoxin by structure-based design. , 1998, Biochemistry.
[10] Homme W. Hellinga,et al. Engineering Biosensors by Introducing Fluorescent Allosteric Signal Transducers: Construction of a Novel Glucose Sensor , 1998 .
[11] S. L. Mayo,et al. De novo protein design: fully automated sequence selection. , 1997, Science.
[12] P S Kim,et al. Repacking protein cores with backbone freedom: structure prediction for coiled coils. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[13] R J Fletterick,et al. X-ray structures of a designed binding site in trypsin show metal-dependent geometry. , 1996, Biochemistry.
[14] L Regan,et al. A tetrahedral zinc(II)-binding site introduced into a designed protein. , 1990, Biochemistry.
[15] Robert Fletterick,et al. Identification of the molecular trigger for allosteric activation in glycogen phosphorylase , 1994, Nature Structural Biology.
[16] Stephen L. Mayo,et al. Design, structure and stability of a hyperthermophilic protein variant , 1998, Nature Structural Biology.
[17] H W Hellinga,et al. Construction of a novel redox protein by rational design: conversion of a disulfide bridge into a mononuclear iron-sulfur center. , 1998, Biochemistry.
[18] B. Matthews,et al. Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme. , 1993, Journal of molecular biology.
[19] H W Hellinga,et al. The rational design and construction of a cuboidal iron-sulfur protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[20] Neil D. Clarke,et al. Novel metal-binding proteins by design , 1995, Nature Structural Biology.
[21] Drexler Ke,et al. Molecular engineering: An approach to the development of general capabilities for molecular manipulation. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[22] F. Arnold,et al. Engineered metal-binding proteins: purification to protein folding. , 1991, Science.
[23] H W Hellinga,et al. Construction of a catalytically active iron superoxide dismutase by rational protein design. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[24] D A Agard,et al. Computational method for the design of enzymes with altered substrate specificity. , 1991, Journal of molecular biology.
[25] J. Ponder,et al. Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes. , 1987, Journal of molecular biology.
[26] C. Pabo,et al. Computer-aided model-building strategies for protein design. , 1986, Biochemistry.
[27] Johan Desmet,et al. The dead-end elimination theorem and its use in protein side-chain positioning , 1992, Nature.
[28] H W Hellinga,et al. The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensors. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[29] F. Arnold. Design by Directed Evolution , 1998 .
[30] Frances H. Arnold,et al. Ruthenium-mediated protein cross-linking and stabilization , 1993 .
[31] F M Richards,et al. Construction of new ligand binding sites in proteins of known structure. II. Grafting of a buried transition metal binding site into Escherichia coli thioredoxin. , 1991, Journal of molecular biology.
[32] S. L. Mayo,et al. Protein design automation , 1996, Protein science : a publication of the Protein Society.
[33] T M Handel,et al. Metal ion-dependent modulation of the dynamics of a designed protein. , 1993, Science.
[34] R. Fletterick,et al. Regulation of serine protease activity by an engineered metal switch. , 1990, Biochemistry.
[35] M. Mutter. The Construction of New Proteins and Enzymes‐a Prospect for the Future? , 1985 .