An apparent paradox: chemokine receptor agonists can be used for anti-inflammatory therapy.
暂无分享,去创建一个
Simi Ali | J. Kirby | G. O'boyle | P. Mellor
[1] T. Williams,et al. The attraction of chemokines as a target for specific anti‐inflammatory therapy , 2006, British journal of pharmacology.
[2] R. Alon,et al. Immune cell migration in inflammation: present and future therapeutic targets , 2005, Nature Immunology.
[3] Marc Parmentier,et al. Dimerization of chemokine receptors and its functional consequences. , 2005, Cytokine & growth factor reviews.
[4] M. Oppermann,et al. G Protein-coupled Receptor Kinases Promote Phosphorylation and β-Arrestin-mediated Internalization of CCR5 Homo- and Hetero-oligomers* , 2005, Journal of Biological Chemistry.
[5] K. Matsushima,et al. The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis. , 2005, International immunology.
[6] J. Isaacs,et al. A Non-Glycosaminoglycan-Binding Variant of CC Chemokine Ligand 7 (Monocyte Chemoattractant Protein-3) Antagonizes Chemokine-Mediated Inflammation1 , 2005, The Journal of Immunology.
[7] R. Horuk,et al. The clinical potential of chemokine receptor antagonists. , 2005, Pharmacology & therapeutics.
[8] Silvia Sebastiani,et al. A rich chemokine environment strongly enhances leukocyte migration and activities. , 2005, Blood.
[9] Waldemar Kolanus,et al. Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines , 2005, Nature Immunology.
[10] Michel Bouvier,et al. Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers* , 2005, Journal of Biological Chemistry.
[11] Guoping Wu,et al. Platelet Factor 4 and Interleukin-8 CXC Chemokine Heterodimer Formation Modulates Function at the Quaternary Structural Level* , 2005, Journal of Biological Chemistry.
[12] M. Parmentier,et al. Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers , 2005, Molecular Pharmacology.
[13] M. Oppermann. Chemokine receptor CCR5: insights into structure, function, and regulation. , 2004, Cellular signalling.
[14] Chongguang Chen,et al. Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. , 2004, European journal of pharmacology.
[15] Simi Ali,et al. Endothelial inflammation: the role of differential expression of N-deacetylase/N-sulphotransferase enzymes in alteration of the immunological properties of heparan sulphate , 2003, Journal of Cell Science.
[16] Simi Ali,et al. Transplant immunobiology: a crucial role for heparan sulfate glycosaminoglycans? , 2003, Transplantation.
[17] Arkadiusz Z Dudek,et al. Platelet factor 4 promotes adhesion of hematopoietic progenitor cells and binds IL-8: novel mechanisms for modulation of hematopoiesis. , 2003, Blood.
[18] T. Rogers,et al. Ca2+-independent Protein Kinase Cs Mediate Heterologous Desensitization of Leukocyte Chemokine Receptors by Opioid Receptors* , 2003, The Journal of Biological Chemistry.
[19] Timothy N. C. Wells,et al. Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[20] Martin Oppermann,et al. β-Arrestin Binding to CC Chemokine Receptor 5 Requires Multiple C-terminal Receptor Phosphorylation Sites and Involves a Conserved Asp-Arg-Tyr Sequence Motif* , 2002, The Journal of Biological Chemistry.
[21] P. Carter. Chemokine receptor antagonism as an approach to anti-inflammatory therapy: 'just right' or plain wrong? , 2002, Current opinion in chemical biology.
[22] Martin Oppermann,et al. Characterization of Sequence Determinants within the Carboxyl-terminal Domain of Chemokine Receptor CCR5 That Regulate Signaling and Receptor Internalization* , 2001, The Journal of Biological Chemistry.
[23] R. Alon,et al. Shear forces promote lymphocyte migration across vascular endothelium bearing apical chemokines , 2001, Nature Immunology.
[24] D. Kerjaschki,et al. The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. , 2001, The American journal of pathology.
[25] A. Lentsch,et al. Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC) , 2000 .
[26] Simi Ali,et al. Examination of the Function of RANTES, MIP-1α, and MIP-1β following Interaction with Heparin-like Glycosaminoglycans* , 2000, The Journal of Biological Chemistry.
[27] A. Zlotnik,et al. Chemokines: a new classification system and their role in immunity. , 2000, Immunity.
[28] R. Snyderman,et al. Chemoattractant Receptors Activate Distinct Pathways for Chemotaxis and Secretion , 1999, The Journal of Biological Chemistry.
[29] C. Martínez-A,et al. The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[30] R. Snyderman,et al. Chemoattractant Receptor Cross-desensitization* , 1999, The Journal of Biological Chemistry.
[31] Robert J. Lefkowitz,et al. G Protein-coupled Receptors , 1998, The Journal of Biological Chemistry.
[32] R. Snyderman,et al. Multiple Signaling Pathways of Human Interleukin-8 Receptor A , 1998, The Journal of Biological Chemistry.
[33] James J. Campbell,et al. Multistep Navigation and the Combinatorial Control of Leukocyte Chemotaxis , 1997, The Journal of cell biology.
[34] R. Snyderman,et al. Cross-desensitization Among Receptors for Platelet Activating Factor and Peptide Chemoattractants , 1996, The Journal of Biological Chemistry.
[35] R. Snyderman,et al. Cross-desensitization of Chemoattractant Receptors Occurs at Multiple Levels , 1995, The Journal of Biological Chemistry.
[36] D. Danilenko,et al. Long-term impaired neutrophil migration in mice overexpressing human interleukin-8. , 1994, The Journal of clinical investigation.
[37] M. Cybulsky,et al. Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules without altering L-selectin expression or leukocyte rolling. , 1993, Journal of immunology.
[38] M. Cybulsky,et al. Intravascular IL-8. Inhibitor of polymorphonuclear leukocyte accumulation at sites of acute inflammation. , 1991, Journal of immunology.
[39] A. M. Lefer,et al. Cardioprotective and endothelial protective effects of [Ala‐IL8]77 in a rabbit model of myocardial ischaemia and reperfusion , 1991, British journal of pharmacology.
[40] R. Hershkoviz,et al. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. , 2003, International immunology.