Rapid assays for environmental and biological monitoring.

Rapid, inexpensive, sensitive, and selective enzyme-linked immunosorbent assays (ELISAs) now are utilized in environmental science. In this laboratory, many ELISAs have been developed for pesticides and other toxic substances and also for their metabolites. Compounds for which ELISAs have recently been devised include insecticides (organophosphates, carbaryl, pyrethroids, and fenoxycarb), herbicides (s-triazines, arylureas, triclopyr, and bromacil), fungicides (myclobutanil), TCDD, and metabolites of naphthalene and toluene. New rapid assays have been developed for mercury.

[1]  David M. Rocke,et al.  An Immunoarray for the Simultaneous Determination of Multiple Triazine Herbicides , 1995 .

[2]  B. Hammock,et al.  Development of Assay for Analysis of Hg2+Based on Sulfur-Containing Ligands , 1995 .

[3]  B. Hammock,et al.  Development of rapid mercury assays. Synthesis of sulfur- and mercury-containing conjugates. , 1995, Bioconjugate chemistry.

[4]  A. Székács,et al.  Development of an enzyme-linked immunosorbent assay for the detection of the triazole fungicide myclobutanil , 1995 .

[5]  Bruce D. Hammock,et al.  A Highly Sensitive and Rapid ELISA for the Arylurea Herbicides Diuron, Monuron, and Linuron , 1994 .

[6]  B. Hammock,et al.  Synthesis of Haptens and Derivation of Monoclonal Antibodies for Immunoassay of the Phenylurea Herbicide Diuron , 1994 .

[7]  Bruce D. Hammock,et al.  Hapten design and development of an ELISA (Enzyme-linked Immunosorbent Assay) for the detection of the mercapturic acid conjugates of naphthalene , 1993 .

[8]  B. Hammock,et al.  An enzyme immunoassay for the environmental monitoring of the herbicide bromacil , 1993 .

[9]  P. Choudary,et al.  Cloning, sequencing and expression of the Fab fragment of a monoclonal antibody to the herbicide atrazine. , 1993, Protein engineering.

[10]  M. Marco,et al.  Development of an enzyme-linked immunosorbent assay for carbaryl , 1993 .

[11]  B D Hammock,et al.  Determination of atrazine metabolites in human urine: development of a biomarker of exposure. , 1993, Chemical research in toxicology.

[12]  M. Marco,et al.  Synthesis of haptens and conjugates for an enzyme immunoassay for analysis of the herbicide bromacil , 1992 .

[13]  B. Hammock,et al.  Influence of the ELISA format and the hapten-enzyme conjugate on the sensitivity of an immunoassay for s-triazine herbicides using monoclonal antibodies , 1992 .

[14]  Bruce D. Hammock,et al.  Development of enzyme-linked immunosorbent assays for 4-nitrophenol and substituted 4-nitrophenols , 1991 .

[15]  Bruce D. Hammock,et al.  Hapten synthesis, antibody development, and competitive inhibition enzyme immunoassay for s-triazine herbicides. , 1990 .

[16]  Bruce D. Hammock,et al.  Use of Immunochemical Techniques for the Analysis of Pesticides , 1989 .