Role of 5‐aminolevulinic acid in the detection of urothelial premalignant lesions

The authors evaluated the role of 5‐aminolevulinic acid (5‐ALA)‐induced fluorescence endoscopy (AFE) in the detection of flat urothelial lesions in light of the suggestions made for flat neoplastic lesions within the 1999 World Health Organization (WHO) classification of urinary bladder tumors.

[1]  L. Sobin,et al.  Histological Typing of Urinary Bladder Tumours , 1999, International Histological Classification of Tumours.

[2]  P Schneede,et al.  Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: results of 1012 fluorescence endoscopies. , 2001, Urology.

[3]  K. Schomacker,et al.  Diagnosis of bladder carcinoma using protoporphyrin IX fluorescence induced by 5‐aminolaevulinic acid , 1999, BJU international.

[4]  A. Althausen,et al.  Non-invasive papillary carcinoma of the bladder associated with carcinoma in situ. , 1976, The Journal of urology.

[5]  G. Steineck,et al.  Epidemiology and Etiology of Premalignant and Malignant Urothelial Changes , 2000, Scandinavian journal of urology and nephrology. Supplementum.

[6]  L. Guillou,et al.  Clinical evaluation of a method for detecting superficial transitional cell carcinoma of the bladder by light‐induced fluorescence of protoporphyrin IX following topical application of 5‐aminolevulinic acid: Preliminary results , 1997, Lasers in surgery and medicine.

[7]  G. Steineck,et al.  Prevention and Treatment of Urothelial Premalignant and Malignant Lesions , 2000, Scandinavian journal of urology and nephrology. Supplementum.

[8]  T. Berge,et al.  Unrecognized renal cell carcinoma. Clinical and diagnostic aspects. , 1981, Scandinavian journal of urology and nephrology.

[9]  L. Kiemeney,et al.  Random bladder biopsies and the risk of recurrent superficial bladder cancer: a prospective study in 1026 patients , 1992, World Journal of Urology.

[10]  F M Debruyne,et al.  Dysplasia in normal-looking urothelium increases the risk of tumour progression in primary superficial bladder cancer. , 1994, European journal of cancer.

[11]  K. Johny,et al.  Xanthomonas maltophilia Infection in Chronic Peritoneal Dialysis Patients , 2000, Scandinavian journal of urology and nephrology.

[12]  S. Wilczynski,et al.  The accuracy of urinary cytology in daily practice , 1999, Cancer.

[13]  K. Kurth.  Diagnosis and treatment of superficial transitional cell carcinoma of the bladder: facts and perspectives. , 1997, European urology.

[14]  C. Busch,et al.  Intraepithelial Lesions of Urinary Bladder: Morphologic Considerations , 2000, Scandinavian journal of urology and nephrology. Supplementum.

[15]  J. Cheville,et al.  Natural history of urothelial dysplasia of the bladder. , 1999, The American journal of surgical pathology.

[16]  M. Melamed,et al.  The relative value of cytometry and cytology in the management of bladder cancer: the Memorial Sloan-Kettering Cancer Center experience. , 1988, Seminars in urology.

[17]  L. M. Franks.  Latent carcinoma of the prostate. , 1954, The Journal of pathology and bacteriology.

[18]  R. Knuechel,et al.  Clinical Results of the Transurethral Resection and Evaluation of Superficial Bladder Carcinomas by Means of Fluorescence Diagnosis after Intravesical Instillation of 5-Aminolevulinic Acid , 1999 .

[19]  R. Knuechel,et al.  Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder. , 2002, Cancer research.

[20]  J. Cheville,et al.  Flat intraepithelial lesions of the urinary bladder , 2000, Cancer.

[21]  M. Soloway,et al.  Serial multiple-site biopsies in patients with bladder cancer. , 1978, The Journal of urology.

[22]  H Stepp,et al.  Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. , 1996, The Journal of urology.