Hemophilia A and Hemophilia B
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[1] D. Perry,et al. AAV5–Factor VIII Gene Transfer in Severe Hemophilia A , 2017, The New England journal of medicine.
[2] Kim Yong Jae,et al. Molecular Design and Characterization of a Novel, Vwf Independent Coagulation Factor VIII (LAFATE) , 2017 .
[3] J. Rasko,et al. Hemophilia B Gene Therapy with a High‐Specific‐Activity Factor IX Variant , 2017, The New England journal of medicine.
[4] Zaina T. Al-Salama,et al. Lonoctocog Alfa: A Review in Haemophilia A , 2017, Drugs.
[5] P. Jiang,et al. Noninvasive detection of F8 int22h-related inversions and sequence variants in maternal plasma of hemophilia carriers. , 2017, Blood.
[6] J. Oldenburg,et al. Emicizumab Prophylaxis in Hemophilia A with Inhibitors , 2017, The New England journal of medicine.
[7] A. Akinc,et al. Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy , 2017, The New England journal of medicine.
[8] J. Astermark,et al. Discrepancies between the one‐stage clotting assay and the chromogenic assay in haemophilia B , 2017, Haemophilia : the official journal of the World Federation of Hemophilia.
[9] V. Blanchette,et al. A systematic review of ultrasound imaging as a tool for evaluating haemophilic arthropathy in children and adults , 2017, Haemophilia : the official journal of the World Federation of Hemophilia.
[10] A. Nienhuis,et al. Gene Therapy for Hemophilia. , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.
[11] D. Perry,et al. Treatment of bleeding episodes with recombinant factor VIII Fc fusion protein in A‐LONG study subjects with severe haemophilia A , 2017, Haemophilia : the official journal of the World Federation of Hemophilia.
[12] S. Kitchen,et al. Factor Activity Assays for Monitoring Extended Half-Life FVIII and Factor IX Replacement Therapies , 2017, Seminars in Thrombosis and Hemostasis.
[13] O. Stasyshyn,et al. Extended half‐life pegylated, full‐length recombinant factor VIII for prophylaxis in children with severe haemophilia A , 2017, Haemophilia : the official journal of the World Federation of Hemophilia.
[14] I. Pabinger,et al. Safety and efficacy of BAY 94‐9027, a prolonged‐half‐life factor VIII , 2017, Journal of thrombosis and haemostasis : JTH.
[15] P. Sax,et al. Ledipasvir–sofosbuvir and sofosbuvir plus ribavirin in patients with chronic hepatitis C and bleeding disorders , 2017, Haemophilia : the official journal of the World Federation of Hemophilia.
[16] R. Ljung,et al. Primary prophylaxis in haemophilia care: Guideline update 2016. , 2017, Blood cells, molecules & diseases.
[17] K. Fischer,et al. Recombinant factor IX Fc fusion protein in children with haemophilia B (Kids B-LONG): results from a multicentre, non-randomised phase 3 study. , 2017, The Lancet. Haematology.
[18] J. Oldenburg,et al. Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B. , 2016, Thrombosis and haemostasis.
[19] J. Hernández-Rivas,et al. Application of a molecular diagnostic algorithm for haemophilia A and B using next-generation sequencing of entire F8, F9 and VWF genes , 2016, Thrombosis and Haemostasis.
[20] F. Peyvandi,et al. Advances in the treatment of bleeding disorders , 2016, Journal of thrombosis and haemostasis : JTH.
[21] A. Iorio,et al. The use of pharmacokinetics in dose individualization of factor VIII in the treatment of hemophilia A , 2016, Expert opinion on drug metabolism & toxicology.
[22] E. Santagostino,et al. Nonacog beta pegol in previously treated children with hemophilia B: results from an international open‐label phase 3 trial , 2016, Journal of thrombosis and haemostasis : JTH.
[23] M. Schemper,et al. FVIII-binding IgG modulates FVIII half-life in patients with severe and moderate hemophilia A without inhibitors. , 2016, Blood.
[24] V. Ramanan,et al. A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A. , 2016, The New England journal of medicine.
[25] T. Humphries,et al. Inhibitors in haemophilia A: a perspective on clotting factor products as a potential contributing factor , 2016, Haemophilia : the official journal of the World Federation of Hemophilia.
[26] J. Peterson,et al. Targeting TFPI for hemophilia treatment. , 2016, Thrombosis research.
[27] F. Horling,et al. Porcine recombinant factor VIII (Obizur; OBI‐1; BAX801): product characteristics and preclinical profile , 2016, Haemophilia : the official journal of the World Federation of Hemophilia.
[28] K. Lyseng-Williamson. Coagulation Factor IX (Recombinant), Albumin Fusion Protein (Albutrepenonacog Alfa; Idelvion®): A Review of Its Use in Haemophilia B , 2016, Drugs.
[29] B. Konkle,et al. Aging among persons with hemophilia: contemporary concerns. , 2016, Seminars in hematology.
[30] A. Srivastava. Inflammation is key to hemophilic arthropathy. , 2015, Blood.
[31] L. Spate,et al. Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk , 2015, Scientific Reports.
[32] A. S. Eraghi,et al. The long-term effects of radioactive phosphorous synoviorthesis on hemophilic arthropathy. , 2015, Blood cells, molecules & diseases.
[33] S. Milstein,et al. An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia , 2015, Nature Medicine.
[34] J. Oldenburg,et al. Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans. , 2015, Blood.
[35] J. Oldenburg,et al. Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial. , 2014, Blood.
[36] Cassandra Willyard. Thrombosis: Balancing act , 2014, Nature.
[37] E. Santagostino,et al. Inhibitors – genetic and environmental factors , 2014, Haemophilia : the official journal of the World Federation of Hemophilia.
[38] J. Dumont,et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. , 2013, The New England journal of medicine.
[39] R. Schaub,et al. Aptamer BAX 499 mediates inhibition of tissue factor pathway inhibitor via interaction with multiple domains of the protein , 2013, Journal of thrombosis and haemostasis : JTH.
[40] J. Oldenburg,et al. Intensity of factor VIII treatment and inhibitor development in children with severe hemophilia A: the RODIN study. , 2013, Blood.
[41] E. Rodríguez‐Merchán. Local fibrin glue and chitosan-based dressings in haemophilia surgery , 2012, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
[42] N. Okada,et al. Liver transplantation for a pediatric patient with hemophilia B , 2012, Pediatric Transplantation.
[43] P. Kouides,et al. How we manage prostate biopsy and prostate cancer therapy in men with haemophilia , 2012, Haemophilia : the official journal of the World Federation of Hemophilia.
[44] J. Dumont,et al. Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients. , 2012, Blood.
[45] L. Valentino,et al. A randomized comparison of two prophylaxis regimens and a paired comparison of on-demand and prophylaxis treatments in hemophilia A management , 2012, Journal of thrombosis and haemostasis : JTH.
[46] C. Hay,et al. The principal results of the International Immune Tolerance Study: a randomized dose comparison. , 2012, Blood.
[47] A. Neff,et al. Survey of current prophylaxis practices and bleeding characteristics of children with severe haemophilia A in US haemophilia treatment centres , 2012, Haemophilia : the official journal of the World Federation of Hemophilia.
[48] R. Kruse-Jarres. Current controversies in the formation and treatment of alloantibodies to factor VIII in congenital hemophilia A. , 2011, Hematology. American Society of Hematology. Education Program.
[49] M. Callaghan,et al. What is the evidence for the use of immunomodulatory agents to eradicate inhibitory antibodies in patients with severe hemophilia a who have previously failed to respond to immune tolerance induction? , 2011, Hematology. American Society of Hematology. Education Program.
[50] P. Cortesi,et al. Anti-inhibitor coagulant complex prophylaxis in hemophilia with inhibitors. , 2011, The New England journal of medicine.
[51] P. Giangrande,et al. Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: a first human dose trial in patients with hemophilia B. , 2011, Blood.
[52] K. High,et al. Gene therapy for haemophilia: a long and winding road , 2011, Journal of thrombosis and haemostasis : JTH.
[53] Hojun Li,et al. In vivo genome editing restores hemostasis in a mouse model of hemophilia , 2011, Nature.
[54] J. Oldenburg,et al. Association between phenotype and genotype in carriers of haemophilia A , 2011, Haemophilia : the official journal of the World Federation of Hemophilia.
[55] J. Astermark,et al. Physical activity and joint function in adults with severe haemophilia on long-term prophylaxis , 2011, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
[56] J. Li,et al. Impact of HIV on liver fibrosis in men with hepatitis C infection and haemophilia , 2011, Haemophilia : the official journal of the World Federation of Hemophilia.
[57] J. Ironside. Variant Creutzfeldt–Jakob disease , 2010, Haemophilia : the official journal of the World Federation of Hemophilia.
[58] P. Kouides,et al. How do we treat: upper gastrointestinal bleeding in adults with haemophilia , 2010, Haemophilia : the official journal of the World Federation of Hemophilia.
[59] P. Kouides,et al. How we treat: patients with haemophilia undergoing screening colonoscopy , 2010, Haemophilia : the official journal of the World Federation of Hemophilia.
[60] Carolyn J Foley,et al. Coronary atherosclerosis and cardiovascular mortality in hemophilia , 2010, Journal of thrombosis and haemostasis : JTH.
[61] P. Mannucci,et al. How I treat age-related morbidities in elderly persons with hemophilia. , 2009, Blood.
[62] R. Fimmers,et al. Impact of polymorphisms of the major histocompatibility complex class II, interleukin‐10, tumor necrosis factor‐α and cytotoxic T‐lymphocyte antigen‐4 genes on inhibitor development in severe hemophilia A , 2009, Journal of thrombosis and haemostasis : JTH.
[63] E. Rogaev,et al. Genotype Analysis Identifies the Cause of the “Royal Disease” , 2009, Science.
[64] C. Kessler,et al. Emerging clinical concerns in the ageing haemophilia patient , 2009, Haemophilia : the official journal of the World Federation of Hemophilia.
[65] M. Manco‐Johnson,et al. Athletic Participation in Severe Hemophilia: Bleeding and Joint Outcomes in Children on Prophylaxis , 2009, Pediatrics.
[66] T. Orfeo,et al. Empirical and theoretical phenotypic discrimination , 2009, Journal of thrombosis and haemostasis : JTH.
[67] G. Roosendaal,et al. Treatment of ischaemic heart disease in haemophilia patients: an institutional guideline , 2009, Haemophilia : the official journal of the World Federation of Hemophilia.
[68] L. Almasy,et al. Inhibitors of factor VIII in black patients with hemophilia. , 2009, The New England journal of medicine.
[69] A. Girolami,et al. Hemospermia in Patients with Congenital Coagulation Disorders: A Study of Three Cases , 2009, Acta Haematologica.
[70] M. Verhaar,et al. Cardiovascular disease in patients with hemophilia , 2009, Journal of thrombosis and haemostasis : JTH.
[71] K. Åkesson,et al. Long‐term prophylaxis in severe haemophilia seems to preserve bone mineral density , 2009, Haemophilia : the official journal of the World Federation of Hemophilia.
[72] G. Young,et al. Single 270 μg kg−1‐dose rFVIIa vs. standard 90 μg kg−1‐dose rFVIIa and APCC for home treatment of joint bleeds in haemophilia patients with inhibitors: a randomized comparison , 2008, Haemophilia : the official journal of the World Federation of Hemophilia.
[73] M. Bullinger,et al. The economics of haemophilia prophylaxis: governmental and insurer perspectives. PROCEEDINGS OF THE SECOND INTERNATIONAL PROPHYLAXIS STUDY GROUP (IPSG) SYMPOSIUM , 2007, Haemophilia : the official journal of the World Federation of Hemophilia.
[74] B. Konkle,et al. Randomized, prospective clinical trial of recombinant factor VIIa for secondary prophylaxis in hemophilia patients with inhibitors , 2007, Journal of thrombosis and haemostasis : JTH.
[75] Alan R. Cohen,et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. , 2007, The New England journal of medicine.
[76] S. Darby,et al. Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV. , 2007, Blood.
[77] J. G. van der Bom,et al. Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study. , 2007, Blood.
[78] G. Young,et al. Individualization of bypassing agent treatment for haemophilic patients with inhibitors utilizing thromboelastography , 2006, Haemophilia : the official journal of the World Federation of Hemophilia.
[79] F. Rosendaal,et al. Mortality and causes of death in patients with hemophilia, 1992–2001: a prospective cohort study 1 , 2006, Journal of thrombosis and haemostasis : JTH.
[80] Christine A. Lee,et al. Detection of known haemophilia B mutations and carrier testing by microarray. , 2005, Thrombosis and haemostasis.
[81] S. Pipe. The promise and challenges of bioengineered recombinant clotting factors , 2005, Journal of thrombosis and haemostasis : JTH.
[82] M. Manco-Johnson,et al. Leukemia and P32 radionuclide synovectomy for hemophilic arthropathy , 2005, Journal of thrombosis and haemostasis : JTH.
[83] P. Babyn,et al. Reliability of progressive and additive MRI scoring systems for evaluation of haemophilic arthropathy in children: Expert MRI Working Group of the International Prophylaxis Study Group , 2005, Haemophilia : the official journal of the World Federation of Hemophilia.
[84] G. Dolan,et al. Mutation analysis in 51 patients with haemophilia A: report of 10 novel mutations and correlations between genotype and clinical phenotype , 2005, Haemophilia : the official journal of the World Federation of Hemophilia.
[85] C. Kessler,et al. B‐domain deleted recombinant factor VIII preparations are bioequivalent to a monoclonal antibody purified plasma‐derived factor VIII concentrate: a randomized, three‐way crossover study , 2005, Haemophilia : the official journal of the World Federation of Hemophilia.
[86] S. Lethagen,et al. Intranasal desmopressin (DDAVP) by spray in mild hemophilia A and von Willebrand's disease type I , 1990, Blut.
[87] J. Lusher,et al. Is the incidence and prevalence of inhibitors greater with recombinant products? No , 2004, Journal of thrombosis and haemostasis : JTH.
[88] J. Ingerslev,et al. Collaborative field study on the utility of a BDD factor VIII concentrate standard in the estimation of BDDr Factor VIII:C activity in hemophilic plasma using one‐stage clotting assays , 2004, Journal of thrombosis and haemostasis : JTH.
[89] L. Valentino. Secondary prophylaxis therapy: what are the benefits, limitations and unknowns? , 2004, Haemophilia : the official journal of the World Federation of Hemophilia.
[90] A. Cumming. The factor VIII gene intron 1 inversion mutation: prevalence in severe hemophilia A patients in the UK , 2004, Journal of thrombosis and haemostasis : JTH.
[91] J. Oldenburg,et al. Environmental and genetic factors influencing inhibitor development. , 2004, Seminars in hematology.
[92] A. Goodeve. The incidence of inhibitor development according to specific mutations - and treatment? , 2003, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
[93] G. Mariani,et al. Immune Tolerance Induction in Hemophilia A: A Review , 2003, Seminars in thrombosis and hemostasis.
[94] M. Manco‐Johnson,et al. 32P Radiosynoviorthesis in Children With Hemophilia , 2002, Journal of pediatric hematology/oncology.
[95] J. Katz,et al. The North American Immune Tolerance Registry: Practices, Outcomes, Outcome Predictors , 2002, Thrombosis and Haemostasis.
[96] G. Gilchrist,et al. Intrauterine correction of factor VIII (FVIII) deficiency , 2001, Haemophilia : the official journal of the World Federation of Hemophilia.
[97] J. Astermark,et al. The Malmö International Brother Study (MIBS): further support for genetic predisposition to inhibitor development , 2001, Haemophilia : the official journal of the World Federation of Hemophilia.
[98] J. Lusher,et al. Perinatal management of newborns with haemophilia , 2001, British journal of haematology.
[99] K. Mann,et al. Issues with the Assay of Factor VIII Activity in Plasma and Factor VIII Concentrates , 2000, Thrombosis and Haemostasis.
[100] Wilde. Protease inhibitor therapy and bleeding , 2000, Haemophilia : the official journal of the World Federation of Hemophilia.
[101] L. Cowan,et al. Mortality among males with hemophilia: relations with source of medical care. The Hemophilia Surveillance System Project Investigators. , 2000, Blood.
[102] J. Gill,et al. Home Treatment of Mild to Moderate Bleeding Episodes Using Recombinant Factor VIIa (Novoseven) in Haemophiliacs with Inhibitors , 1998, Thrombosis and Haemostasis.
[103] C. Kessler,et al. Advances in carrier detection in haemophilia , 1998, Haemophilia : the official journal of the World Federation of Hemophilia.
[104] Adam I. Wacey,et al. The factor VIII Structure and Mutation Resource Site: HAMSTeRS version 4 , 1998, Nucleic Acids Res..
[105] B. Nielsen,et al. Recombinant Factor IX , 1997, Thrombosis and Haemostasis.
[106] J. T. ten Cate,et al. Recombinant, B-domain Deleted Factor VIII (r-VIII SQ): Pharmacokinetics and Initial Safety Aspects in Hemophilia A Patients , 1997, Thrombosis and Haemostasis.
[107] I. Warrier,et al. F, Spiro I: Posttransplantation lymphoproliferative disorders in solid Nephrotic Syndrome as a Complication of Immune Tolerance in Hemophilia B , 1997 .
[108] M. Goossens,et al. Haemophilia B: database of point mutations and short additions and deletions, 7th edition , 1990, Nucleic Acids Res..
[109] J. Katz,et al. Factor IX inhibitors and anaphylaxis in hemophilia B. , 1997, Journal of pediatric hematology/oncology.
[110] E. Rodríguez‐Merchán. Pathogenesis, early diagnosis, and prophylaxis for chronic hemophilic synovitis. , 1997, Clinical orthopaedics and related research.
[111] F. Rosendaal,et al. Mortality in Patients with Hemophilia: Changes in a Dutch Population from 1986 to 1992 and 1973 to 1986 , 1995, Annals of Internal Medicine.
[112] F E Preston,et al. Factor VIII gene inversions in severe hemophilia A: results of an international consortium study. , 1995, Blood.
[113] M. van den Berg,et al. The Nijmegen Modification of the Bethesda Assay for Factor VIII:C Inhibitors: Improved Specificity and Reliability , 1995, Thrombosis and Haemostasis.
[114] E. C. Rodríguez Merchán. The haemophilic pseudotumour , 1995, International Orthopaedics.
[115] H. Pettersson,et al. A longitudinal study of orthopaedic outcomes for severe factor‐VIII‐deficient haemophiliacs , 1994, Journal of internal medicine.
[116] M. Manco‐Johnson,et al. Results of secondary prophylaxis in children with severe hemophilia , 1994, American journal of hematology.
[117] J. Luck,et al. Hemarthrosis and synovitis associated with hemophilia: clinical use of P-32 chromic phosphate synoviorthesis for treatment. , 1994, Radiology.
[118] U. Martinowitz,et al. Dental extractions in patients with bleeding disorders. The use of fibrin glue. , 1993, Oral surgery, oral medicine, and oral pathology.
[119] S. Schulman,et al. Adjusted dose continuous infusion of factor VIII in patients with haemophilia A , 1992, British journal of haematology.
[120] J. Fernández,et al. Update of 156 episodes of central nervous system bleeding in hemophiliacs. , 1992, Haemostasis.
[121] C. Kasper,et al. Response of patients with mild and moderate hemophilia A and von Willebrand's disease to treatment with desmopressin. , 1985, Annals of internal medicine.
[122] C. Kitchens,et al. Spontaneous intra-abdominal hemorrhage in hemophilia. , 1984, Archives of internal medicine.
[123] C. Kitchens. Occult hemophilia. , 1980, The Johns Hopkins medical journal.
[124] Björn Gustavii,et al. FETOSCOPY , 1979, Acta obstetricia et gynecologica Scandinavica.
[125] C. Mcmillan,et al. SEVERE FACTOR VIII AND FACTOR IX DEFICIENCY IN FEMALES: 629 , 1978 .
[126] C. Kitchens. Retropharyngeal hematoma in a hemophiliac. , 1977, Southern medical journal.
[127] D. Green,et al. Proceedings: A more uniform measurement of factor VIII inhibitors. , 1975, Thrombosis et diathesis haemorrhagica.
[128] J. Lewis,et al. Heckathorn's disease: variable functional dificiency of antihemophilic factor (factor VIII). , 1975, Blood.
[129] R. Biggs,et al. The Mode of Action of Antibodies which Destroy Factor VIII , 1972, British journal of haematology.