Pre-mRNA splicing in the new millennium.

[1]  R. Reed,et al.  An Upstream AG Determines Whether a Downstream AG Is Selected during Catalytic Step II of Splicing , 2001, Molecular and Cellular Biology.

[2]  J. V. Moran,et al.  Initial sequencing and analysis of the human genome. , 2001, Nature.

[3]  Xiangdong Xu,et al.  SC35 plays a role in T cell development and alternative splicing of CD45. , 2001, Molecular cell.

[4]  C. Guthrie,et al.  Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. , 2001, Genes & development.

[5]  A. Krainer,et al.  Pre-mRNA splicing in the absence of an SR protein RS domain. , 2000, Genes & development.

[6]  R. Lin,et al.  Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome , 2000, Nature.

[7]  B. Schwer,et al.  RNA helicase dynamics in pre‐mRNA splicing , 2000, The EMBO journal.

[8]  Susan M. Berget,et al.  An Intronic Splicing Enhancer Binds U1 snRNPs To Enhance Splicing and Select 5′ Splice Sites , 2000, Molecular and Cellular Biology.

[9]  M. Hagiwara,et al.  SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development , 2000, Mechanisms of Development.

[10]  A. Karpova,et al.  Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene. , 2000, Genes & development.

[11]  A. Krainer,et al.  Selection of Alternative 5′ Splice Sites: Role of U1 snRNP and Models for the Antagonistic Effects of SF2/ASF and hnRNP A1 , 2000, Molecular and Cellular Biology.

[12]  J. Valcárcel,et al.  The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. , 2000, Molecular cell.

[13]  D. Black Protein Diversity from Alternative Splicing A Challenge for Bioinformatics and Post-Genome Biology , 2000, Cell.

[14]  D. Black,et al.  Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein , 2000, Molecular and Cellular Biology.

[15]  C. Guthrie,et al.  The question remains: Is the spliceosome a ribozyme? , 2000, Nature Structural Biology.

[16]  Russ P. Carstens,et al.  An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein , 2000, Molecular and Cellular Biology.

[17]  J. Stévenin,et al.  The RNA-Binding Protein TIA-1 Is a Novel Mammalian Splicing Regulator Acting through Intron Sequences Adjacent to a 5′ Splice Site , 2000, Molecular and Cellular Biology.

[18]  B. Graveley Sorting out the complexity of SR protein functions. , 2000, RNA.

[19]  L. Chasin,et al.  Multiple Splicing Defects in an Intronic False Exon , 2000, Molecular and Cellular Biology.

[20]  R Kole,et al.  Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Potashkin,et al.  Analysis of the splicing machinery in fission yeast: a comparison with budding yeast and mammals. , 2000, Nucleic acids research.

[22]  S. Stamm,et al.  Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2). , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[23]  T. Nilsen,et al.  Functional recognition of 5' splice site by U4/U6.U5 tri-snRNP defines a novel ATP-dependent step in early spliceosome assembly. , 2000, Molecular cell.

[24]  M. Ares,et al.  A yeast intronic splicing enhancer and Nam8p are required for Mer1p-activated splicing. , 2000, Molecular cell.

[25]  J. Valcárcel,et al.  Alternative pre-mRNA splicing: the logic of combinatorial control. , 2000, Trends in biochemical sciences.

[26]  Stephen M. Mount,et al.  Pre-Messenger RNA Processing Factors in the Drosophila Genome , 2000, The Journal of cell biology.

[27]  T. Kawano,et al.  Unique and redundant functions of SR proteins, a conserved family of splicing factors, in Caenorhabditis elegans development , 2000, Mechanisms of Development.

[28]  J. C. Clemens,et al.  Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity , 2000, Cell.

[29]  R. Darnell,et al.  A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Alison M. Goate,et al.  Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17 , 2000, Molecular and Cellular Biology.

[31]  D L Black,et al.  Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. , 2000, Molecular cell.

[32]  J. Lewis,et al.  Like attracts like: getting RNA processing together in the nucleus. , 2000, Science.

[33]  R. Reed,et al.  Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. , 2000, Molecular cell.

[34]  B. Séraphin,et al.  A dual role for BBP/ScSF1 in nuclear pre‐mRNA retention and splicing , 2000, The EMBO journal.

[35]  A. Krainer,et al.  The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation , 2000, The Journal of cell biology.

[36]  J. Cáceres,et al.  Functional characterization of SR and SR‐related genes in Caenorhabditis elegans , 2000, The EMBO journal.

[37]  Kevin Burrage,et al.  ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome , 2000, Nature Genetics.

[38]  B. Blencowe Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases. , 2000, Trends in biochemical sciences.

[39]  T. Cooper,et al.  RNA processing and human disease , 2000, Cellular and Molecular Life Sciences CMLS.

[40]  X. Estivill,et al.  Mutations affecting mRNA splicing are the most common molecular defects in patients with neurofibromatosis type 1. , 2000, Human molecular genetics.

[41]  C. Lorson,et al.  An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN. , 2000, Human molecular genetics.

[42]  M. Moore,et al.  Evidence for a linear search in bimolecular 3' splice site AG selection. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[43]  T. Maniatis,et al.  Role of adenine functional groups in the recognition of the 3'-splice-site AG during the second step of pre-mRNA splicing. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[44]  J. Lis,et al.  Pre-mRNA Splicing by the EssentialDrosophila Protein B52: Tissue and Target Specificity , 2000, Molecular and Cellular Biology.

[45]  M. Ares,et al.  ATP can be dispensable for prespliceosome formation in yeast. , 2000, Genes & development.

[46]  M. Gelfand,et al.  Frequent alternative splicing of human genes. , 1999, Genome research.

[47]  Sara G. Becker-Catania,et al.  Splicing defects in the ataxia-telangiectasia gene, ATM: underlying mutations and consequences. , 1999, American journal of human genetics.

[48]  Stephen M. Mount,et al.  Genetic enhancement of RNA-processing defects by a dominant mutation in B52, the Drosophila gene for an SR protein splicing factor , 1995, Molecular and cellular biology.

[49]  J. Lis,et al.  The SR protein B52/SRp55 is essential for Drosophila development , 1994, Molecular and cellular biology.

[50]  D. Mccormick Sequence the Human Genome , 1986, Bio/Technology.

[51]  J. Steitz,et al.  Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome. , 2001, Molecular cell.

[52]  International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome , 2001, Nature.

[53]  Michael Q. Zhang,et al.  A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes , 2001, Nature Genetics.

[54]  S. Stamm,et al.  Htra 2-b 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 ( SMN 2 ) , 2000 .

[55]  J. G. Patton,et al.  Identification and Characterization of a Novel Serine-Arginine-Rich Splicing Regulatory Protein , 2022 .