A new approach towards ultrasonic transmission tomography with a standard ultrasound system

The capability of ultrasound transmission tomography to reconstruct acoustic parameters of proven histological relevance like acoustic speed and attenuation has been established over the past few decades by several researchers. The approach taken so far was a fully custom designed transmission tomography system which is a considerably multifaceted venture. The outcome of the earlier research proved the feasibility of the concept but fell short of the clinical requirements due to its inadequate spatial resolution and reconstruction accuracy on one hand and its experimental nature on the other hand. The major consideration behind the novel approach presented here is to make use of a commercially available ultrasound system and to supplement it with an add-on module, the latter being designed to extend the function of the former to realize a transmission ultrasound mode. The ultrasound transmission data of an object, when acquired from multiple directions, allows spatially resolved tomographic reconstruction of parameters like acoustic speed and acoustic attenuation. The use of a standard ultrasound system makes the acquisition of transmission as well as echo data of the whole object possible; the latter allows a further processing for three dimensional rendering of the echosonographic image, compounding and tissue characterization based on multiple parameters.

[1]  P Kozlowski,et al.  [Criteria of dignity in ultrasound mammography using a 10-MHz-transducer, also with regard to tumor size]. , 2003, Ultraschall in der Medizin.

[2]  Helmut Ermert,et al.  Ultrasound Spiral Computed Tomography for Differential Diagnosis of Breast Tumors Using a Conventional Ultrasound System , 2004 .

[3]  T A Whittingham,et al.  Experimental studies in transmission ultrasound computed tomography. , 1991, Physics in medicine and biology.

[4]  A. Pesavento,et al.  Ultrasonic Breast Imaging Assisted by Acoustic Velocity Reconstruction , 1997 .

[5]  Avinash C. Kak,et al.  Signal Processing of Broadband Pulsed Ultrasound: Measurement of Attenuation of Soft Biological Tissues , 1978, IEEE Transactions on Biomedical Engineering.

[6]  H. Ermert,et al.  System Analysis of Ultrasound Reflection Mode Computerized Tomography , 1984, IEEE Transactions on Sonics and Ultrasonics.

[7]  J. Greenleaf,et al.  ALGEBRAIC RECONSTRUCTION OF SPATIAL DISTRIBUTIONS OF ACOUSTIC VELOCITIES IN TISSUE FROM THEIR TIME-OF-FLIGHT PROFILES. , 1975 .

[8]  W. Roßdeutscher,et al.  Eine neue sonografische Methode zur Untersuchung der Brust. A New Sonographic Method of Examining the Breast , 1995 .

[9]  H. Ermert,et al.  A modified time-of-flight tomography concept for ultrasonic breast imaging , 1996, 1996 IEEE Ultrasonics Symposium. Proceedings.

[10]  H. Ermert,et al.  Estimation of time of flight for ultrasonic reflex-transmission tomography with active contour models , 2004, IEEE Ultrasonics Symposium, 2004.

[11]  K. A. Dines,et al.  Ultrasonic Attenuation Tomography of Soft Tissues , 1979 .

[12]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[13]  Robert J. Eckersley,et al.  2005 IEEE Ultrasonics Symposium, Vols 1-4 , 2005 .

[14]  Helmut Ermert,et al.  Limited angle ultrasonic transmission tomography of the compressed female breast , 1998, 1998 IEEE Ultrasonics Symposium. Proceedings (Cat. No. 98CH36102).

[15]  J R Jago An automatic method for determining the centre of rotation of a mechanically scanned UCT system , 1994 .

[16]  Ramesh C. Jain,et al.  Using Dynamic Programming for Solving Variational Problems in Vision , 1990, IEEE Trans. Pattern Anal. Mach. Intell..