Serum lipids, lipoproteins and apolipoprotein E phenotypes in relatives of patients with type III hyperlipoproteinaemia

Abstract. Eighty‐six relatives of nineteen probands with type III hyperlipoproteinaemia were studied to determine the occurrence of hyperlipidaemia and to investigate the relation between apo E phenotypes, the occurrence of hyperlipidaemia, and the composition of the very low density lipoprotein (VLDL) fraction. Thirty‐nine relatives were hyperlipidaemic: four type IIa or IIb, nine type III and twenty‐six type IV. The predisposition for hyperlipidaemia was independent of the apo E phenotype.

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