Efficacy and safety of a new peeling formulated with a pool of PHAs for the treatment of all skin types, even sensitive

Actually, the use of chemical peels in cosmetics and dermatology continues to grow due to their versatility, clinical endpoint–directed predictability, and favorable risk profile in comparison to lasers. The chemical peel is a generally safe method for treatment of some skin disorders and to refresh and rejuvenate the skin. The major challenge of chemical peels is the tolerability, that is because of sensitive skin which is one of the most common skin disorders.

[1]  H. Rotsztejn,et al.  Corneometric evaluation of skin moisture after application of 10% and 30% gluconolactone , 2021, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[2]  C. Granger,et al.  A Treatment Combination of Peels, Oral Antioxidants, and Topical Therapy for Refractory Melasma: A Report of 4 Cases , 2020, Clinical, cosmetic and investigational dermatology.

[3]  H. Rotsztejn,et al.  Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss , 2019, Journal of cosmetic dermatology.

[4]  C. Wambier,et al.  Basic chemical peeling-superficial and medium-depth peels. , 2019, Journal of the American Academy of Dermatology.

[5]  P. Asawanonda,et al.  The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study , 2019, Clinical, cosmetic and investigational dermatology.

[6]  H. Rotsztejn,et al.  Lactic and lactobionic acids as typically moisturizing compounds , 2018, International journal of dermatology.

[7]  Z. Rahman,et al.  A Practical Approach to Chemical Peels: A Review of Fundamentals and Step-by-step Algorithmic Protocol for Treatment. , 2018, The Journal of clinical and aesthetic dermatology.

[8]  I. Costa,et al.  Review in peeling complications , 2017, Journal of cosmetic dermatology.

[9]  D. Pedroso,et al.  Sensitive skin: review of an ascending concept* , 2017, Anais brasileiros de dermatologia.

[10]  Marta Ferreira,et al.  Improvement of the methods for skin mechanical properties evaluation through correlation between different techniques and factor analysis , 2013, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[11]  H. Maibach,et al.  Sensitive skin: an overview , 2013, International journal of cosmetic science.

[12]  H. Maibach,et al.  Sensitive Skin: Sensory, Clinical and Physiological Factors , 2009 .

[13]  José Juan Escobar-Chávez,et al.  The tape-stripping technique as a method for drug quantification in skin. , 2008, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

[14]  H. Maibach,et al.  Bioengineering Analysis of Water Hydration: An Overview , 2003, Exogenous Dermatology.

[15]  J. Wilkinson,et al.  Sensitive skin: an epidemiological study , 2001, The British journal of dermatology.

[16]  D Black,et al.  Skin topography measurement by interference fringe projection: a technical validation , 2001, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[17]  M. Lóden Biophysical properties of dry atopic and normal skin with special reference to effects of skin care products. , 1995, Acta dermato-venereologica. Supplementum.

[18]  T. Agner,et al.  Guidelines for transepidermal water loss (TEWL) measurement , 1990, Contact dermatitis.

[19]  Christiane,et al.  World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. , 2004, Journal international de bioethique = International journal of bioethics.

[20]  C. Blichmann,et al.  Assessment of skin moisture. Measurement of electrical conductance, capacitance and transepidermal water loss. , 1988, Acta dermato-venereologica.

[21]  Brenda L. Edison,et al.  Antiaging Effects of Topical Lactobionic Acid : Results of a Controlled Usage Study , 2022 .