An international retrospective study for tolerability of 6-mercaptopurine on NUDT15 bi-allelic variants in children with acute lymphoblastic leukemia
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Hsi-Che Liu | Motohiro Kato | A. Yeoh | H. Ariffin | E. Ito | Chi-kong Li | Jun J. Yang | T. Ueda | J. Buaboonnam | A. Manabe | H. Hori | Masaki Yamamoto | Hui Zhang | Takaya Moriyama | R. Nishii | Yoichi Tanaka | A. Ohara | K. Koh | J. Fujimura | A. Sato | Yuki Arakawa | D. Hasegawa | S. Kham | D. Keino | K. Kondoh | M. Hino | Zhiwei Chen | K. Kudo | Y. Taneyama | M. Takagi | M. Kato | Jassada Buaboonnam
[1] S. Igel,et al. Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry , 2019, Genetics in Medicine.
[2] M. Relling,et al. Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT15 Genotypes: 2018 Update , 2019, Clinical pharmacology and therapeutics.
[3] Minu Singh,et al. Prevalence of TPMT, ITPA and NUDT 15 genetic polymorphisms and their relation to 6MP toxicity in north Indian children with acute lymphoblastic leukemia , 2018, Cancer Chemotherapy and Pharmacology.
[4] J. Takita,et al. Diplotype analysis of NUDT15 variants and 6-mercaptopurine sensitivity in pediatric lymphoid neoplasms , 2018, Leukemia.
[5] U. Hofmann,et al. Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy. , 2018, Blood.
[6] Motohiro Kato,et al. Treatment and biology of pediatric acute lymphoblastic leukemia , 2018, Pediatrics international : official journal of the Japan Pediatric Society.
[7] N. G. Sheppard,et al. NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. , 2016, Cancer research.
[8] U. Hofmann,et al. NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity , 2016, Nature Genetics.
[9] Motohiro Kato,et al. Susceptibility to 6‐MP toxicity conferred by a NUDT15 variant in Japanese children with acute lymphoblastic leukaemia , 2015, British journal of haematology.
[10] M. Relling,et al. Inherited NUDT15 variant is a genetic determinant of mercaptopurine intolerance in children with acute lymphoblastic leukemia. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] Jianjun Liu,et al. A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia , 2014, Nature Genetics.
[12] Y. Cheung,et al. Predictive role of NUDT15 variants on thiopurine-induced myelotoxicity in Asian inflammatory bowel disease patients. , 2018, Pharmacogenomics.