Pro-inflammatory cytokines in stress-induced depression: Novel insights into mechanisms and promising therapeutic strategies

[1]  Keyue Tian,et al.  Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy , 2023, Journal of Hematology & Oncology.

[2]  Li Ma,et al.  Brain methylome remodeling selectively regulates neuronal activity genes linking to emotional behaviors in mice exposed to maternal immune activation , 2023, Nature communications.

[3]  Anbiao Wu,et al.  Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis , 2023, Journal of Neuroinflammation.

[4]  T. Gur,et al.  The Maternal Microbiome as a Map to Understanding the Impact of Prenatal Stress on Offspring Psychiatric Health , 2023, Biological Psychiatry.

[5]  Jingxu Chen,et al.  Systemic inflammation and oxidative stress markers in patients with unipolar and bipolar depression: A large-scale study. , 2023, Journal of Affective Disorders.

[6]  E. Hoxha,et al.  Differential diagnosis of unipolar versus bipolar depression by GSK3 levels in peripheral blood: a pilot experimental study , 2023, International Journal of Bipolar Disorders.

[7]  Yun-Shin Jung,et al.  Multifaceted role of CD14 in innate immunity and tissue homeostasis. , 2023, Cytokine & growth factor reviews.

[8]  E. Riboli,et al.  Lipopolysaccharide-binding protein and future Parkinson’s disease risk: a European prospective cohort , 2023, Journal of Neuroinflammation.

[9]  P. Cowen,et al.  The pharmacological bases for repurposing statins in depression: a review of mechanistic studies , 2023, Translational psychiatry.

[10]  R. Hen,et al.  A complex relation between levels of adult hippocampal neurogenesis and expression of the immature neuron marker doublecortin , 2023, Hippocampus.

[11]  A. Zepeda,et al.  The impact of maternal immune activation on the morphology and electrophysiological properties of postnatally-born neurons in the offspring , 2023, Neural regeneration research.

[12]  D. Pavlov,et al.  Maternal Chronic Ultrasound Stress Provokes Immune Activation and Behavioral Deficits in the Offspring: A Mouse Model of Neurodevelopmental Pathology , 2023, International journal of molecular sciences.

[13]  M. Nishibori,et al.  Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice , 2023, Cells.

[14]  Wenzheng Wu,et al.  Exploring New Mechanism of Depression from the Effects of Virus on Nerve Cells , 2023, Cells.

[15]  L. Bettendorff.  Synthetic Thioesters of Thiamine: Promising Tools for Slowing Progression of Neurodegenerative Diseases , 2023, International journal of molecular sciences.

[16]  Mingxing Li,et al.  Caspase-1 affects chronic restraint stress-induced depression-like behaviors by modifying GABAergic dysfunction in the hippocampus , 2023, Translational psychiatry.

[17]  Yingming Li,et al.  Lipopolysaccharide-induced depression-like model in mice: meta-analysis and systematic evaluation , 2023, Frontiers in Immunology.

[18]  Quanguang Zhang,et al.  Early life adversity as a risk factor for cognitive impairment and Alzheimer’s disease , 2023, Translational Neurodegeneration.

[19]  P. Hof,et al.  Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures , 2023, Acta Neuropathologica Communications.

[20]  Yiran Huang,et al.  T cells: an emerging cast of roles in bipolar disorder , 2023, Translational psychiatry.

[21]  C. Bucolo,et al.  Fluoxetine Protects Retinal Ischemic Damage in Mice , 2023, Pharmaceutics.

[22]  Sung-Wan Kim,et al.  Age-specific associations between inflammatory markers and remission of depression during antidepressant use , 2023, Psychiatry Research.

[23]  Xiaorong Zhou,et al.  Canthin-6-Ones: Potential Drugs for Chronic Inflammatory Diseases by Targeting Multiple Inflammatory Mediators , 2023, Molecules.

[24]  Yuan Zhang,et al.  Peripheral cytokine levels across psychiatric disorders: A systematic review and network meta-analysis , 2023, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[25]  J. Felger,et al.  Inflammation-Related Functional and Structural Dysconnectivity as a Pathway to Psychopathology , 2023, Biological Psychiatry.

[26]  V. Ravichandiran,et al.  4-Methylesculetin ameliorates LPS-induced depression-like behavior through the inhibition of NLRP3 inflammasome , 2023, Frontiers in Pharmacology.

[27]  N. Vale,et al.  Oxidative Stress in Depression: The Link with the Stress Response, Neuroinflammation, Serotonin, Neurogenesis and Synaptic Plasticity , 2023, Antioxidants.

[28]  Jun Ma,et al.  Affective neural circuits and inflammatory markers linked to depression and anxiety symptoms in patients with comorbid obesity. , 2023, Journal of psychiatric research.

[29]  C. Zarate,et al.  Inflammation, stress and depression: an exploration of ketamine's therapeutic profile. , 2023, Drug discovery today.

[30]  J. Neill,et al.  Maternal behaviours and adult offspring behavioural deficits are predicted by maternal TNFα concentration in a rat model of neurodevelopmental disorders , 2022, Brain, Behavior, and Immunity.

[31]  P. Gaskill,et al.  Dopamine, Immunity, and Disease , 2022, Pharmacological Reviews.

[32]  T. Suppes,et al.  Novel and emerging treatments for major depression , 2022, The Lancet.

[33]  P. Cuijpers,et al.  Effects of psychological treatment for depression among people not actively seeking help: a meta-analysis , 2022, Psychological Medicine.

[34]  T. Moffitt,et al.  Major depression and the biological hallmarks of aging , 2022, Ageing Research Reviews.

[35]  M. Saladin,et al.  The role of exercise in the treatment of depression: biological underpinnings and clinical outcomes , 2022, Molecular Psychiatry.

[36]  C. Vargas,et al.  High-protein nutrition during pregnancy increases neuroinflammation and homocysteine levels and impairs behavior in male adolescent rats offspring. , 2022, Life sciences.

[37]  C. Lauber,et al.  Maternal anxiety, depression and stress affects offspring gut microbiome diversity and bifidobacterial abundances , 2022, Brain, Behavior, and Immunity.

[38]  R. Rubin,et al.  Blood concentrations of neopterin and biopterin in subjects with depression: A systematic review and meta-analysis , 2022, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[39]  A. Sartorius,et al.  Hippocampal neuroplasticity, major depression and, not to forget: ECT , 2022, Molecular Psychiatry.

[40]  M. Newman,et al.  Prospective network analysis of proinflammatory proteins, lipid markers, and depression components in midlife community women , 2022, Psychological Medicine.

[41]  Jing Wang,et al.  Prevention and treatment of natural products from Traditional Chinese Medicine in depression: Potential targets and mechanisms of action , 2022, Frontiers in aging neuroscience.

[42]  E. Galván,et al.  Maternal immune activation increases excitability via downregulation of A-type potassium channels and reduces dendritic complexity of hippocampal neurons of the offspring , 2022, Brain, Behavior, and Immunity.

[43]  J. Shiea,et al.  Isobaric Tags for Relative and Absolute Quantitation Identification of Blood Proteins Relevant to Paroxetine Response in Patients With Major Depressive Disorder , 2022, Frontiers in Psychiatry.

[44]  D. Rubinow,et al.  Transcriptome-wide association study for postpartum depression implicates altered B-cell activation and insulin resistance , 2022, Molecular Psychiatry.

[45]  T. Pietras,et al.  Chemokine (C–C motif) ligand 5 (RANTES) concentrations in the peripheral blood of patients with a depressive disorder , 2022, Pharmacological Reports.

[46]  K. Lesch,et al.  Hippocampal Over-Expression of Cyclooxygenase-2 (COX-2) Is Associated with Susceptibility to Stress-Induced Anhedonia in Mice , 2022, International journal of molecular sciences.

[47]  J. Szemraj,et al.  Inflammatory Markers and Episodic Memory Functioning in Depressive Disorders , 2022, Journal of clinical medicine.

[48]  J. Hodgson,et al.  Prenatal Poly I:C Challenge Affects Behaviors and Neurotransmission via Elevated Neuroinflammation Responses in Female Juvenile Rats , 2021, The international journal of neuropsychopharmacology.

[49]  Shuiqing Huang,et al.  Anti-depressive effects of Jiao-Tai-Wan on CORT-induced depression in mice by inhibiting inflammation and microglia activation. , 2021, Journal of ethnopharmacology.

[50]  D. Geschwind,et al.  Maternal Immune Activation during Pregnancy Alters Postnatal Brain Growth and Cognitive Development in Nonhuman Primate Offspring , 2021, The Journal of Neuroscience.

[51]  M. Perreault,et al.  Glycogen Synthase Kinase-3: A Focal Point for Advancing Pathogenic Inflammation in Depression , 2021, Cells.

[52]  Rajasa Randhi,et al.  Selective inhibition of soluble TNF using XPro1595 improves hippocampal pathology to promote improved neurological recovery following traumatic brain injury in mice. , 2021, CNS and Neurological Disorders - Drug Targets.

[53]  M. Berk,et al.  Translational evidence for the Inflammatory Response System (IRS)/Compensatory Immune Response System (CIRS) and neuroprogression theory of major depression , 2021, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[54]  J. Duan,et al.  Chinese Medicine Formula Kai-Xin-San Ameliorates Neuronal Inflammation of CUMS-Induced Depression-like Mice and Reduces the Expressions of Inflammatory Factors via Inhibiting TLR4/IKK/NF-κB Pathways on BV2 Cells , 2021, Frontiers in Pharmacology.

[55]  N. Chen,et al.  The receptor hypothesis and the pathogenesis of depression: genetic bases and biological correlates. , 2021, Pharmacological research.

[56]  N. Jaafari,et al.  On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos? , 2021, Journal of neuroinflammation.

[57]  R. Rupprecht,et al.  Association of Chemokine (C-C Motif) Receptor 5 and Ligand 5 with Recovery from Major Depressive Disorder and Related Neurocognitive Impairment , 2021, Neuroimmunomodulation.

[58]  M. Irwin,et al.  The IL-6 antagonist tocilizumab is associated with worse depression and related symptoms in the medically ill , 2021, Translational Psychiatry.

[59]  J. Veijola,et al.  Associations Between Maternal Prenatal C-Reactive Protein and Risk Factors for Psychosis in Adolescent Offspring: Findings From the Northern Finland Birth Cohort 1986 , 2020, Schizophrenia bulletin.

[60]  Till F. M. Andlauer,et al.  Fatigue, depression, and pain in multiple sclerosis: How neuroinflammation translates into dysfunctional reward processing and anhedonic symptoms , 2020, Multiple sclerosis.

[61]  J. Chang,et al.  Genetic Variations of Ionotropic Glutamate Receptor Pathways on Interferon-α-induced Depression in Patients with Hepatitis C Viral Infection , 2020, Brain, Behavior, and Immunity.

[62]  Yong Cheng,et al.  Serum Exosome-Derived miR-139-5p as a Potential Biomarker for Major Depressive Disorder , 2020, Neuropsychiatric disease and treatment.

[63]  N. Rocha,et al.  Brain-derived neurotrophic factor (BDNF) and inflammatory markers: Perspectives for the management of depression , 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[64]  M. Matteoli,et al.  Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on? , 2020, Translational Psychiatry.

[65]  J. Sheridan,et al.  Stress, inflammation and depression: A new possible molecular pathway , 2020, Brain, Behavior, and Immunity.

[66]  Hailan Hu,et al.  Microglia in depression: current perspectives , 2020, Science China Life Sciences.

[67]  R. Cui,et al.  Effect of Early Life Stress on the Epigenetic Profiles in Depression , 2020, Frontiers in Cell and Developmental Biology.

[68]  Y. Fang,et al.  Common cellular and molecular mechanisms and interactions between microglial activation and aberrant neuroplasticity in depression , 2020, Neuropharmacology.

[69]  A. Marsland,et al.  Longitudinal relationships of cytokines, depression and anhedonia in depressed adolescents , 2020, Brain, Behavior, and Immunity.

[70]  L. Bettendorff,et al.  Dibenzoylthiamine Has Powerful Antioxidant and Anti-Inflammatory Properties in Cultured Cells and in Mouse Models of Stress and Neurodegeneration , 2020, Biomedicines.

[71]  A. Minelli,et al.  Blues in the Brain and Beyond: Molecular Bases of Major Depressive Disorder and Relative Pharmacological and Non-Pharmacological Treatments , 2020, Genes.

[72]  Constanza de Dios,et al.  Effect of immune activation on the kynurenine pathway and depression symptoms – A systematic review and meta-analysis , 2020, Neuroscience & Biobehavioral Reviews.

[73]  V. Arolt,et al.  Childhood trauma, suicide risk and inflammatory phenotypes of depression: insights from monocyte gene expression , 2020, Translational Psychiatry.

[74]  Fanet H,et al.  Tetrahydrobioterin (BH4) pathway: from metabolism to neuropsychiatry. , 2020, Current neuropharmacology.

[75]  S. Wood,et al.  Advances in understanding mechanisms and therapeutic targets to treat comorbid depression and cardiovascular disease , 2020, Neuroscience & Biobehavioral Reviews.

[76]  C. Nemeroff,et al.  The Bidirectional Relationship of Depression and Inflammation: Double Trouble , 2020, Neuron.

[77]  D. Hermann,et al.  Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model , 2020, Molecular Neurobiology.

[78]  S. Tiosano,et al.  The impact of tocilizumab on anxiety and depression in patients with rheumatoid arthritis. , 2020, European journal of clinical investigation.

[79]  Yasushi Kobayashi,et al.  Investigation of the impact of preconditioning with lipopolysaccharide on inflammation-induced gene expression in the brain and depression-like behavior in male mice , 2020, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[80]  F. Jessen,et al.  Depression—an underrecognized target for prevention of dementia in Alzheimer’s disease , 2020, Translational Psychiatry.

[81]  Chandragouda R. Patil,et al.  Role of oxidative stress in depression. , 2020, Drug discovery today.

[82]  Nicole E. Carmona,et al.  Efficacy of adjunctive infliximab vs. placebo in the treatment of anhedonia in bipolar I/II depression , 2020, Brain, Behavior, and Immunity.

[83]  R. Cui,et al.  Potential role of insulin on the pathogenesis of depression , 2020, Cell proliferation.

[84]  B. Czéh,et al.  Stress-Induced Morphological, Cellular and Molecular Changes in the Brain—Lessons Learned from the Chronic Mild Stress Model of Depression , 2020, Cells.

[85]  S. Di Nuovo,et al.  The cytokine network in the pathogenesis of major depressive disorder. Close to translation? , 2020, Autoimmunity reviews.

[86]  A. Sartorius,et al.  Cytokine-mediated cellular immune activation in electroconvulsive therapy: A CSF study in patients with treatment-resistant depression , 2020, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.

[87]  Yong Cheng,et al.  Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis , 2020, Neuropsychopharmacology.

[88]  Lijing Zhu,et al.  Si-Ni-San Prevents Reserpine-Induced Depression by Inhibiting Inflammation and Regulating CYP450 Enzymatic Activity , 2020, Frontiers in Pharmacology.

[89]  D. Goldsmith,et al.  Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression , 2020, Neuropsychopharmacology.

[90]  Andrew H. Miller.  Beyond depression: the expanding role of inflammation in psychiatric disorders , 2020, World psychiatry : official journal of the World Psychiatric Association.

[91]  T. Dinan,et al.  Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome. , 2020, Annual review of psychology.

[92]  M. Irwin,et al.  Novel neuroimmunologic therapeutics in depression: A clinical perspective on what we know so far , 2020, Brain, Behavior, and Immunity.

[93]  B. Birnir,et al.  Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers , 2019, International journal of molecular sciences.

[94]  R. Duman,et al.  Neuroplasticity in cognitive and psychological mechanisms of depression: An integrative model , 2019, Molecular Psychiatry.

[95]  C. Pariante,et al.  Markers of central inflammation in major depressive disorder: A systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue , 2019, Brain, Behavior, and Immunity.

[96]  S. Maier,et al.  Microglia: Neuroimmune-sensors of stress. , 2019, Seminars in cell & developmental biology.

[97]  Nicole E. Carmona,et al.  Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial. , 2019, JAMA psychiatry.

[98]  M. Herkenham,et al.  The Behavioral Sequelae of Social Defeat Require Microglia and Are Driven by Oxidative Stress in Mice , 2019, The Journal of Neuroscience.

[99]  B. Penninx,et al.  Longitudinal Association Between Depression and Inflammatory Markers: Results From the Netherlands Study of Depression and Anxiety , 2019, Biological Psychiatry.

[100]  A. Zonderman,et al.  Systemic inflammation is associated with depressive symptoms differentially by sex and race: a longitudinal study of urban adults , 2019, Molecular Psychiatry.

[101]  M. Hotopf,et al.  Inflammatory profiles of severe treatment-resistant depression. , 2019, Journal of affective disorders.

[102]  A. Teixeira,et al.  Inflammation in psychiatric disorders: what comes first? , 2019, Annals of the New York Academy of Sciences.

[103]  C. Cotman,et al.  Inhibition of LTP-Induced Translation by IL-1β Reduces the Level of Newly Synthesized Proteins in Hippocampal Dendrites. , 2019, ACS chemical neuroscience.

[104]  Steve W. C. Chang,et al.  From Stress to Anhedonia: Molecular Processes through Functional Circuits , 2019, Trends in Neurosciences.

[105]  Runa Bhaumik,et al.  Innate immunity in the postmortem brain of depressed and suicide subjects: Role of Toll-like receptors , 2019, Brain, Behavior, and Immunity.

[106]  M. Craske,et al.  The role of inflammation in core features of depression: Insights from paradigms using exogenously-induced inflammation , 2018, Neuroscience & Biobehavioral Reviews.

[107]  A. Zepeda,et al.  Systemic Inflammation Impairs Proliferation of Hippocampal Type 2 Intermediate Precursor Cells , 2018, Cellular and Molecular Neurobiology.

[108]  D. Goldsmith,et al.  Antidepressant treatment resistance is associated with increased inflammatory markers in patients with major depressive disorder , 2018, Psychoneuroendocrinology.

[109]  C. Nemeroff,et al.  Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response , 2018, Neuron.

[110]  S. Narumiya,et al.  The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation , 2018, Neuron.

[111]  A. Fahimi,et al.  Immune and Neuroprotective Effects of Physical Activity on the Brain in Depression , 2018, Front. Neurosci..

[112]  Cai Song,et al.  Mifepristone attenuates depression-like changes induced by chronic central administration of interleukin-1β in rats , 2018, Behavioural Brain Research.

[113]  Adwitia Dey,et al.  Insights into Macrophage Heterogeneity and Cytokine-Induced Neuroinflammation in Major Depressive Disorder , 2018, Pharmaceuticals.

[114]  D. Goldsmith,et al.  What does plasma CRP tell us about peripheral and central inflammation in depression? , 2018, Molecular Psychiatry.

[115]  Yuan Yang,et al.  Changes in the serum levels of inflammatory cytokines in antidepressant drug-naïve patients with major depression , 2018, PloS one.

[116]  C. Cotman,et al.  IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation , 2018, Journal of Neuroinflammation.

[117]  M. Leboyer,et al.  Immune-based strategies for mood disorders: facts and challenges , 2018, Expert review of neurotherapeutics.

[118]  Qiu-qin Han,et al.  Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats , 2018, Journal of Neuroinflammation.

[119]  S. Russo,et al.  Inflammatory Mediators in Mood Disorders: Therapeutic Opportunities. , 2018, Annual review of pharmacology and toxicology.

[120]  J. Kucharska-Mazur,et al.  Cytokine alterations and cognitive impairment in major depressive disorder: From putative mechanisms to novel treatment targets , 2018, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[121]  C. Pariante,et al.  Rescue of IL-1β-induced reduction of human neurogenesis by omega-3 fatty acids and antidepressants , 2017, Brain, Behavior, and Immunity.

[122]  Hanjie Yu,et al.  Lentivirus-mediated interleukin-1β (IL-1β) knock-down in the hippocampus alleviates lipopolysaccharide (LPS)-induced memory deficits and anxiety- and depression-like behaviors in mice , 2017, Journal of Neuroinflammation.

[123]  S. Nakagawa,et al.  Neural basis of major depressive disorder: Beyond monoamine hypothesis , 2017, Psychiatry and clinical neurosciences.

[124]  A. Young,et al.  Minocycline as an adjunct for treatment-resistant depressive symptoms: A pilot randomised placebo-controlled trial , 2017, Journal of psychopharmacology.

[125]  J. Radulovic,et al.  Therapeutic Strategies for Treatment of Inflammation-related Depression , 2017, Current neuropharmacology.

[126]  L. Bettendorff,et al.  Thiamine and benfotiamine prevent stress-induced suppression of hippocampal neurogenesis in mice exposed to predation without affecting brain thiamine diphosphate levels , 2017, Molecular and Cellular Neuroscience.

[127]  K. Hashimoto,et al.  Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis , 2017, Translational Psychiatry.

[128]  T. Hyphantis,et al.  Depression in cancer: The many biobehavioral pathways driving tumor progression. , 2017, Cancer treatment reviews.

[129]  R. Dantzer,et al.  Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions , 2016, Molecular Psychiatry.

[130]  K. Kirkby,et al.  Inflammation and Immune Regulation as Potential Drug Targets in Antidepressant Treatment , 2016, Current neuropharmacology.

[131]  C. Pariante,et al.  Genetic Contributions of Inflammation to Depression , 2016, Neuropsychopharmacology.

[132]  I. Mancilla-Herrera,et al.  The Immune System and the Role of Inflammation in Perinatal Depression , 2016, Neuroscience Bulletin.

[133]  R. Dantzer,et al.  Inflammation Models of Depression in Rodents: Relevance to Psychotropic Drug Discovery , 2016, The international journal of neuropsychopharmacology.

[134]  G. Aghajanian,et al.  Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants , 2016, Nature Medicine.

[135]  V. Felipo,et al.  Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane , 2016, Journal of Neuroinflammation.

[136]  A. Miller,et al.  Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression , 2016, Molecular Psychiatry.

[137]  Yong-Ku Kim,et al.  The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression , 2016, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[138]  Andrew H. Miller,et al.  The role of inflammation in depression: from evolutionary imperative to modern treatment target , 2015, Nature Reviews Immunology.

[139]  F. Balcı,et al.  TNF-alpha inhibition prevents cognitive decline and maintains hippocampal BDNF levels in the unpredictable chronic mild stress rat model of depression , 2015, Behavioural Brain Research.

[140]  Miriam Merad,et al.  Neuroimmune mechanisms of depression , 2015, Nature Neuroscience.

[141]  K. Michelsen,et al.  Chronic intestinal inflammation alters hippocampal neurogenesis , 2015, Journal of Neuroinflammation.

[142]  W. Qin,et al.  Role for Pro-inflammatory Cytokines in Regulating Expression of GABA Transporter Type 1 and 3 in Specific Brain Regions of Kainic Acid-Induced Status Epilepticus , 2015, Neurochemical Research.

[143]  C. Hammen,et al.  Effects of Chronic Interpersonal Stress Exposure on Depressive Symptoms are Moderated by Genetic Variation at IL6 and IL1β in Youth , 2015, Brain, Behavior, and Immunity.

[144]  O. Mors,et al.  Effect of anti-inflammatory treatment on depression, depressive symptoms, and adverse effects: a systematic review and meta-analysis of randomized clinical trials. , 2014, JAMA psychiatry.

[145]  D. Ditor,et al.  The common inflammatory etiology of depression and cognitive impairment: a therapeutic target , 2014, Journal of Neuroinflammation.

[146]  M. Irwin,et al.  From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. , 2014, Psychological bulletin.

[147]  A. Sawa,et al.  Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application , 2014, Translational Psychiatry.

[148]  R. Duman,et al.  The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses , 2013, Brain, Behavior, and Immunity.

[149]  Andrew H. Miller,et al.  CYTOKINE TARGETS IN THE BRAIN: IMPACT ON NEUROTRANSMITTERS AND NEUROCIRCUITS , 2013, Depression and anxiety.

[150]  A Suzumura,et al.  Minocycline selectively inhibits M1 polarization of microglia , 2013, Cell Death and Disease.

[151]  G. Aghajanian,et al.  Synaptic Dysfunction in Depression: Potential Therapeutic Targets , 2012, Science.

[152]  G. Hankey,et al.  Aspirin decreases the risk of depression in older men with high plasma homocysteine , 2012, Translational Psychiatry.

[153]  M. O’Banion,et al.  Adult murine hippocampal neurogenesis is inhibited by sustained IL-1β and not rescued by voluntary running , 2012, Brain, Behavior, and Immunity.

[154]  G. Turecki,et al.  Astrocytic Hypertrophy in Anterior Cingulate White Matter of Depressed Suicides , 2011, Neuropsychopharmacology.

[155]  J. Mann,et al.  Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder , 2011, Brain, Behavior, and Immunity.

[156]  A. Menter,et al.  The effect of adalimumab on reducing depression symptoms in patients with moderate to severe psoriasis: a randomized clinical trial. , 2010, Journal of the American Academy of Dermatology.

[157]  S. Lunte,et al.  Inflammation as the common biological link between depression and cardiovascular diseases: Can carnosine exert a protective role? , 2019, Current medicinal chemistry.

[158]  S. Russo,et al.  Immune and Neuroendocrine Mechanisms of Stress Vulnerability and Resilience , 2017, Neuropsychopharmacology.

[159]  M. Treadway,et al.  Inflammation Effects on Motivation and Motor Activity: Role of Dopamine , 2017, Neuropsychopharmacology.

[160]  D. F. Drake,et al.  A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. , 2013, JAMA psychiatry.