论文信息 - Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction - 字舞流文

Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction

W. Lew | Q. Wang | M. A. Ischay | D. Steinhuebel | Matthew R. Chin | J. Tripp | Darryl D. Dixon | Lars V. Heumann | Brittanie Hoang | Nisha P. Shah | D. A. Mundal | Danielle Elfgren | Sean T. Neville | Bing Shi

[1] J. Nakatani,et al. Preparation of Trifluoromethylphenyl Magnesium Halides in the Presence of LiCl and Synthesis of 2′-Trifluoromethyl-Aromatic Ketones , 2016 .

[2] Arun K. Ghosh,et al. Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS. , 2016, Journal of medicinal chemistry.

[3] D. Zisterer,et al. Aromatic bis-N-hydroxyguanidinium derivatives: synthesis, biophysical, and biochemical evaluations. , 2013, Journal of medicinal chemistry.

[4] L. Overman,et al. On the structure of palau'amine: evidence for the revised relative configuration from chemical synthesis. , 2007, Journal of the American Chemical Society.

[5] J. Wiss,et al. Explosion and Decomposition Characteristics of Hydrazoic Acid in the Gas Phase , 2007 .

[6] S. Abrecht,et al. The synthetic-technical development of oseltamivir phosphate Tamiflu™ : A race against time , 2007 .

[7] M. Marletta,et al. NG-hydroxyguanidines from primary amines. , 2006, Organic letters.

[8] P. Knochel,et al. A LiCl-mediated Br/Mg exchange reaction for the preparation of functionalized aryl- and heteroarylmagnesium compounds from organic bromides. , 2004, Angewandte Chemie.