Structure and regulation of opioid receptors.
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K. Chaturvedi | R. Howells | K Chaturvedi | K H Christoffers | K Singh | R D Howells | K. Christoffers | K. Singh | Kamalendra Singh | Richard D. Howells | Richard D. Howells
[1] P. Cuatrecasas,et al. Interactions of ligands with morphine and enkephalin receptors are differentially affected by guanine nucleotide. , 1981, Molecular pharmacology.
[2] R. Howells,et al. Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide. , 1996, The Journal of biological chemistry.
[3] C. Strader,et al. Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function. , 1988, The Journal of biological chemistry.
[4] C Evans,et al. The conserved aspartate residue in the third putative transmembrane domain of the delta-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site. , 1996, Molecular pharmacology.
[5] T. Reisine,et al. Mutagenesis of a Single Amino Acid in the Rat μ‐Opioid Receptor Discriminates Ligand Binding , 1998, Journal of neurochemistry.
[6] D. Lissin,et al. mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain. , 1998, Molecular pharmacology.
[7] J. Benovic,et al. β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor , 1996, Nature.
[8] S. Snyder,et al. Opiate Receptor: Demonstration in Nervous Tissue , 1973, Science.
[9] K. Tanaka. Proteasomes: structure and biology. , 1998, Journal of biochemistry.
[10] H. Mori,et al. Stepwise Movement of Preproteins in the Process of Translocation across the Cytoplasmic Membrane of Escherichia coli(*) , 1995, The Journal of Biological Chemistry.
[11] C. Chen,et al. The third extracellular loop of the mu opioid receptor is important for agonist selectivity. , 1995, The Journal of biological chemistry.
[12] E. J. Simon,et al. Stereospecific binding of the potent narcotic analgesic (3H) Etorphine to rat-brain homogenate. , 1973, Proceedings of the National Academy of Sciences of the United States of America.
[13] S. Snyder,et al. Differential Regulation by Guanine Nucleotides of Opiate Agonist and Antagonist Receptor Interactions , 1980, Journal of neurochemistry.
[14] D. Lissin,et al. δ and κ Opioid Receptors Are Differentially Regulated by Dynamin-dependent Endocytosis When Activated by the Same Alkaloid Agonist* , 1997, The Journal of Biological Chemistry.
[15] R. Howells,et al. Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[16] C. Strader,et al. Allele-specific activation of genetically engineered receptors. , 1991, The Journal of biological chemistry.
[17] G. Uhl,et al. Human kappa opiate receptor second extracellular loop elevates dynorphin's affinity for human mu/kappa chimeras. , 1994, The Journal of biological chemistry.
[18] C. Wahlestedt,et al. Novel “Restoration of Function” Mutagenesis Strategy to Identify Amino Acids of the δ-Opioid Receptor Involved in Ligand Binding* , 1997, The Journal of Biological Chemistry.
[19] P. van Kerkhof,et al. Endocytosis and Degradation of the Growth Hormone Receptor Are Proteasome-dependent* , 2000, The Journal of Biological Chemistry.
[20] A. S. Bogachuk,et al. Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated , 1988, FEBS letters.
[21] Claes Wahlestedt,et al. Involvement of Trp-284, Val-296, and Val-297 of the Human δ-Opioid Receptor in Binding of δ-Selective Ligands* , 1996, Journal of Biological Chemistry.
[22] R. Robinson,et al. CXII.—The morphine group. Part I. A discussion of the constitutional problem , 1923 .
[23] P. Penela,et al. Degradation of the G Protein-coupled Receptor Kinase 2 by the Proteasome Pathway* , 1998, The Journal of Biological Chemistry.
[24] L. Terenius. Stereospecific interaction between narcotic analgesics and a synaptic plasm a membrane fraction of rat cerebral cortex. , 2009, Acta pharmacologica et toxicologica.
[25] John Hughes,et al. Endogenous opioid peptides: multiple agonists and receptors , 1977, Nature.
[26] R. Edwards,et al. Cloning of a delta opioid receptor by functional expression. , 1992, Science.
[27] L. Hicke. Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels. , 1999, Trends in cell biology.
[28] M. Comb,et al. A Mitogen-activated Protein Kinase Pathway Is Required for μ-Opioid Receptor Desensitization* , 1998, The Journal of Biological Chemistry.
[29] D. Filliol,et al. Constitutive Activation of the δ Opioid Receptor by Mutations in Transmembrane Domains III and VII* , 1999, The Journal of Biological Chemistry.
[30] Yi-Jun Guo,et al. Molecular basis for the interaction of histamine with the histamine H2 receptor. , 1992, The Journal of biological chemistry.
[31] R. Lefkowitz,et al. β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC , 2000, The Journal of Biological Chemistry.
[32] L. Devi,et al. Dimerization of the delta opioid receptor: implication for a role in receptor internalization. , 1997, The Journal of biological chemistry.
[33] Robert J. Lefkowitz,et al. G Protein-coupled Receptors , 1998, The Journal of Biological Chemistry.
[34] A. Ciechanover,et al. The ubiquitin system. , 1998, Annual review of biochemistry.
[35] Robert C. Thompson,et al. A Chimeric Study of the Molecular Basis of Affinity and Selectivity of the κ and the δ Opioid Receptors. , 1995, The Journal of Biological Chemistry.
[36] P. Breuer,et al. Stabilization of Mutant 46-kDa Mannose 6-Phosphate Receptors by Proteasomal Inhibitor Lactacystin* , 1998, The Journal of Biological Chemistry.
[37] L. Devi,et al. Thr, Located within the COOH-terminal Tail of the Opiate Receptor, Is Involved in Receptor Down-regulation (*) , 1996, The Journal of Biological Chemistry.
[38] H. Lester,et al. The role of conserved aspartate and serine residues in ligand binding and in function of the 5‐HT1A receptor: A site‐directed mutation study , 1992, FEBS letters.
[39] Robert C. Thompson,et al. Mapping the receptor domains critical for the binding selectivity of δ-opioid receptor ligands , 1996 .
[40] L. Hood,et al. Porcine pituitary dynorphin: complete amino acid sequence of the biologically active heptadecapeptide. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[41] H Hayashi,et al. Site-directed mutagenesis of the histamine H1 receptor: roles of aspartic acid107, asparagine198 and threonine194. , 1994, Biochemical and biophysical research communications.
[42] B. Carter,et al. Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[43] H. Loh,et al. Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[44] Y. Chen,et al. Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. , 1993, The Biochemical journal.
[45] S. Ōmura,et al. Degradation Process of Ligand-stimulated Platelet-derived Growth Factor β -Receptor Involves Ubiquitin-Proteasome Proteolytic Pathway * , 1995, Journal of Biological Chemistry.
[46] Stanley J. Watson,et al. Cloning and pharmacological characterization of a rat μ opioid receptor , 1993, Neuron.
[47] A Goldstein,et al. Cloning and pharmacological characterization of a rat kappa opioid receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[48] C. Fraser,et al. Site-directed mutagenesis of alpha 2A-adrenergic receptors: identification of amino acids involved in ligand binding and receptor activation by agonists. , 1991, Molecular pharmacology.
[49] T. Nakagawa,et al. DAMGO, a μ‐opioid receptor selective agonist, distinguishes between μ‐ and δ‐opioid receptors around their first extracellular loops , 1995 .
[50] G. Uhl,et al. mu opiate receptor: cDNA cloning and expression. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[51] Q. Deveraux,et al. A 26 S protease subunit that binds ubiquitin conjugates. , 1994, The Journal of biological chemistry.
[52] J. Whistler,et al. Morphine-activated opioid receptors elude desensitization by β-arrestin , 1998 .
[53] G. Schultz,et al. μ and δ opioid receptors differentially couple to G protein subtypes in membranes of human neuroblastoma SH-SY5Y cells , 1993, Neuron.
[54] G. Uhl,et al. Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. , 1994, FEBS letters.
[55] L. Devi,et al. Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalization. , 1996, The Journal of biological chemistry.
[56] H. Loh,et al. Molecular mechanisms and regulation of opioid receptor signaling. , 2000, Annual review of pharmacology and toxicology.
[57] C. Zioudrou,et al. Effect of δ-opioid antagonists on the functional coupling between opioid receptors and G-proteins in rat brain membranes , 1993 .
[58] H. Kosterlitz,et al. CHARACTERIZATION OF THE k‐SUBTYPE OF THE OPIATE RECEPTOR IN THE GUINEA‐PIG BRAIN , 1981 .
[59] K. Palczewski,et al. Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor , 2002, Chembiochem : a European journal of chemical biology.
[60] J. Wess,et al. Molecular basis of receptor/G-protein-coupling selectivity. , 1998, Pharmacology & therapeutics.
[61] W. Schütz,et al. Reverse intrinsic activity of antagonists on G protein-coupled receptors. , 1992, Trends in pharmacological sciences.
[62] E. J. Simon,et al. Opioid Receptor Multiplicity: Isolation, Purification, and Chemical Characterization of Binding Sites , 1993 .
[63] S. Udenfriend,et al. Characterization of rimorphin, a new [leu]enkephalin-containing peptide from bovine posterior pituitary glands. , 1982, Life sciences.
[64] S. Udenfriend,et al. Biochemistry of the enkephalins and enkephalin-containing peptides. , 1983, Archives of biochemistry and biophysics.
[65] D Rodbard,et al. Drug efficacy at guanine nucleotide-binding regulatory protein-linked receptors: thermodynamic interpretation of negative antagonism and of receptor activity in the absence of ligand. , 1992, Molecular pharmacology.
[66] A. Goldstein,et al. Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[67] G. Koski,et al. Opiates inhibit adenylate cyclase by stimulating GTP hydrolysis. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[68] H. Morris,et al. Identification of two related pentapeptides from the brain with potent opiate agonist activity , 1975, Nature.
[69] M. Obin,et al. Ubiquitinylation and Ubiquitin-dependent Proteolysis in Vertebrate Photoreceptors (Rod Outer Segments) , 1996, The Journal of Biological Chemistry.
[70] M. von Zastrow,et al. Type-specific Sorting of G Protein-coupled Receptors after Endocytosis* , 2000, Journal of Biological Chemistry.
[71] M. Abood,et al. Molecular cloning and expression of a δ‐opioid recetpor from rat brain , 1994, Journal of neuroscience research.
[72] M. Shahrestanifar,et al. Sensitivity of μ and ∂ opioid receptor binding to N-ethylmaleimide , 1994, Regulatory Peptides.
[73] R. Lefkowitz,et al. Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C. , 1995, Molecular pharmacology.
[74] E. Kornilova,et al. Lysosomal Targeting of Epidermal Growth Factor Receptors via a Kinase-dependent Pathway Is Mediated by the Receptor Carboxyl-terminal Residues 1022-1123* , 1996, The Journal of Biological Chemistry.
[75] H. Akil,et al. Key Residues Defining the μ‐Opioid Receptor Binding Pocket: A Site‐Directed Mutagenesis Study , 1997, Journal of neurochemistry.
[76] H. Loh,et al. Molecular characterization of opioid receptors. , 1990, Annual review of pharmacology and toxicology.
[77] J. Venter,et al. Site-directed mutagenesis of m1 muscarinic acetylcholine receptors: conserved aspartic acids play important roles in receptor function. , 1989, Molecular pharmacology.
[78] P. Portoghese,et al. A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding. , 1993, The Journal of biological chemistry.
[79] E. Hulme,et al. C fragment of lipotropin has a high affinity for brain opiate receptors , 1976, Nature.
[80] Brigitte L. Kieffer,et al. Role of Aromatic Transmembrane Residues of the -Opioid Receptor in Ligand Recognition (*) , 1996, The Journal of Biological Chemistry.
[81] M. Zastrow,et al. Downregulation of G protein-coupled receptors , 2000, Current Opinion in Neurobiology.
[82] K. Chaturvedi,et al. μ Opioid receptor: role for the amino terminus as a determinant of ligand binding affinity , 2000 .
[83] A Herz,et al. Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[84] L. Hicke,et al. A function for monoubiquitination in the internalization of a G protein-coupled receptor. , 1998, Molecular cell.
[85] G. Dondio,et al. Pharmacological profiles of selective non-peptidic δ opioid receptor ligands , 2000 .
[86] A. Blume. Opiate binding to membrane preparations of neuroblastoma x glioma hybrid cells NG108-15: effects of ions and nucleotides. , 1978, Life sciences.
[87] M. Billeter,et al. MOLMOL: a program for display and analysis of macromolecular structures. , 1996, Journal of molecular graphics.
[88] Lei Yu,et al. Molecular cloning and functional expression of a mu opioid receptor from rat brain , 1994, Regulatory Peptides.
[89] M. Caron,et al. Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. , 1989, The Journal of biological chemistry.
[90] G. Milligan,et al. Agonist activation of p42 and p44 mitogen-activated protein kinases following expression of the mouse delta opioid receptor in Rat-1 fibroblasts: effects of receptor expression levels and comparisons with G-protein activation. , 1996, The Biochemical journal.
[91] D. Grandy,et al. Analysis of selective binding epitopes for the kappa-opioid receptor antagonist nor-binaltorphimine. , 1995, Molecular pharmacology.
[92] G. Uhl,et al. -mu opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity. , 1994, The Journal of biological chemistry.
[93] S. Ōmura,et al. Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway , 1997, Molecular and cellular biology.
[94] M. Caron,et al. Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization , 1996, Science.
[95] A. Strosberg,et al. Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. , 1999, The Journal of biological chemistry.
[96] S. Snyder,et al. Differential effects of protein-modifying reagents on receptor binding of opiate agonists and antagonists. , 1975, Molecular pharmacology.
[97] H. Loh,et al. Ability of delta-opioid receptors to interact with multiple G-proteins is independent of receptor density. , 1994, The Journal of biological chemistry.
[98] Christopher J. Evans,et al. Morphine Activates Opioid Receptors without Causing Their Rapid Internalization* , 1996, The Journal of Biological Chemistry.
[99] E. J. Simon,et al. Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[100] N. E. Larsen,et al. Protection of opiate receptors in NG108-15 against modification by N- ethylmaleimide , 1983, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[101] S. Kato,et al. Location of Regions of the Opioid Receptor Involved in Selective Agonist Binding (*) , 1995, The Journal of Biological Chemistry.
[102] H. Loh,et al. Visualization of time-dependent redistribution of delta-opioid receptors in neuronal cells during prolonged agonist exposure. , 1999, Brain research. Molecular brain research.
[103] P. Seeburg,et al. Molecular characterization of a new immunoglobulin superfamily protein with potential roles in opioid binding and cell contact. , 1989, The EMBO journal.
[104] F. Medzihradsky,et al. Receptor-mediated stimulation of brain GTPase by opiates in normal and dependent rats. , 1984, Biochemical and biophysical research communications.
[105] K. Befort,et al. The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[106] E. J. Simon,et al. Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization*. , 2000, Biochemical pharmacology.
[107] G. Bell,et al. Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[108] T. Nakagawa,et al. DAMGO, a μ‐opioid receptor selective ligand, distinguishes between μ‐and κ‐opioid receptors at a different region from that for the distinction between μ‐ and δ‐opioid receptors , 1995 .
[109] K. Fukuda,et al. Identification of the amino acid residues involved in selective agonist binding in the first extracellular loop of the δ‐ and μ‐opioid receptors , 1995 .
[110] J. K. de Riel,et al. Characterization of Irreversible Binding of -Funaltrexamine to the Cloned Rat Opioid Receptor (*) , 1995, The Journal of Biological Chemistry.
[111] Howard Riezman,et al. Ubiquitination of a Yeast Plasma Membrane Receptor Signals Its Ligand-Stimulated Endocytosis , 1996, Cell.
[112] C. Chen,et al. Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor. , 1994, The Journal of biological chemistry.
[113] M. Nishi,et al. Primary structures and expression from cDNAs of rat opioid receptor δ‐and μ‐subtypes , 1993 .
[114] A. Gingras,et al. μ-Opioid Receptor Activates Signaling Pathways Implicated in Cell Survival and Translational Control* , 1998, The Journal of Biological Chemistry.