Reservoirs of antimicrobial resistance in pet animals.

Increasing amounts of antimicrobials are used in pets, including substances used in human medicine (in particular, broad-spectrum agents such as clavulante-potentiated aminopenicillins, cephalosporins, and fluoroquinolones). There is evidence that resistance to antimicrobials is growing among bacteria causing infection in pets. These bacteria include Staphylococcus intermedius and Escherichia coli, as well as other organisms of clinical importance in humans, including methicillin-resistant Staphylococcus aureus. Transmission of such organisms, particularly pathogenic staphylococci, occurs between pets, owners, and veterinary staff, and pets can act as reservoirs of such bacteria; this may have an impact on the use of antimicrobials in human medicine. There is a need to generate data regarding both the levels of carriage of such bacteria in pets and the risk factors associated with the transfer of the bacteria to humans who have contact with infected pets, as well as to improve hygiene measures in veterinary practice.

[1]  W. Noble,et al.  Nasal Carriage of Staphylococcus intermedius in Humans in Contact with Dogs , 1994 .

[2]  W. Lilenbaum,et al.  Prevalence and antimicrobial susceptibility of staphylococci isolated from the skin surface of clinically normal cats , 1998, Letters in applied microbiology.

[3]  A. Esteves,et al.  Prevalence and antimicrobial susceptibility of staphylococci isolated from saliva of clinically normal cats , 1999, Letters in applied microbiology.

[4]  W. Noble,et al.  Fluoroquinolone resistance in Staphylococcus intermedius. , 1999, Veterinary dermatology.

[5]  J. Pellerin,et al.  Epidemiosurveillance of antimicrobial compound resistance of Staphylococcus intermedium clinical isolates from canine pyodermas. , 1998, Comparative immunology, microbiology and infectious diseases.

[6]  D. Lloyd,et al.  Antimicrobial resistance of feline staphylococci in south-eastern England. , 1999, Veterinary dermatology.

[7]  P. Muir,et al.  Methicillin-resistant Staphylococcus aureus infections in 11 dogs , 1999, Veterinary Record.

[8]  C. Greko,et al.  Antimicrobial resistance in staphylococci from canine pyoderma: a prospective study of first-time and recurrent cases in Sweden , 2002, Veterinary Record.

[9]  F. Aarestrup,et al.  Priorities for antibiotic resistance surveillance in Europe. , 2006, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[10]  L. Guardabassi,et al.  Overlooked aspects concerning development and spread of antimicrobial resistance , 2003, Expert review of anti-infective therapy.

[11]  Stefan Schwarz,et al.  Pet animals as reservoirs of antimicrobial-resistant bacteria. , 2004, The Journal of antimicrobial chemotherapy.

[12]  F. Manian.  Asymptomatic nasal carriage of mupirocin-resistant, methicillin-resistant Staphylococcus aureus (MRSA) in a pet dog associated with MRSA infection in household contacts. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[13]  J. Nicolet,et al.  [The current antimicrobial resistance situation in Swiss veterinary medicine]. , 2001, Schweizer Archiv fur Tierheilkunde.

[14]  M. Rich.  Staphylococci in animals: prevalence, identification and antimicrobial susceptibility, with an emphasis on methicillin-resistant Staphylococcus aureus , 2005, British journal of biomedical science.

[15]  D. Lloyd,et al.  Sensitivity to antibiotics amongst cutaneous and mucosal isolates of canine pathogenic staphylococci in the UK, 1980-96. , 1996, Veterinary dermatology.

[16]  F. Shofer,et al.  Screening of Staphylococcus aureus, Staphylococcus intermedius, and Staphylococcus schleiferi isolates obtained from small companion animals for antimicrobial resistance: a retrospective review of 749 isolates (2003-04). , 2006, Veterinary dermatology.

[17]  L. Guardabassi,et al.  Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners. , 2004, Veterinary microbiology.

[18]  B. Markey,et al.  Methicillin-resistant Staphylococcus aureus (MRSA) isolated from animals and veterinary personnel in Ireland. , 2005, Veterinary microbiology.

[19]  Stephen J. DeVincent,et al.  Introduction to animal antimicrobial use data collection in the United States: methodological options. , 2006, Preventive veterinary medicine.

[20]  C. Greko,et al.  Antibacterial Drugs Prescribed for Dogs and Cats in Sweden and Norway 1990–1998 , 2001, Acta veterinaria Scandinavica.

[21]  J. Mikalsen,et al.  Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway , 2004 .

[22]  V. Jensen,et al.  Antimicrobial Drug Consumption in Companion Animals , 2005, Emerging infectious diseases.

[23]  R. Bywater.  Veterinary use of antimicrobials and emergence of resistance in zoonotic and sentinel bacteria in the EU. , 2004, Journal of veterinary medicine. B, Infectious diseases and veterinary public health.

[24]  J. P. Sheridan.  BRITISH SMALL ANIMAL VETERINARY ASSOCIATION , 1970 .

[25]  H. Kruse,et al.  The antimicrobial susceptibility of Staphylococcus species isolated from canine dermatitis , 2004, Veterinary Research Communications.

[26]  H. Deluyker,et al.  A European survey of antimicrobial susceptibility among zoonotic and commensal bacteria isolated from food-producing animals. , 2004, The Journal of antimicrobial chemotherapy.

[27]  L. Roberts,et al.  Methicillin-resistant Staphylococcus aureus isolates from companion animals. , 2004, The Veterinary record.

[28]  A. Dalsgaard,et al.  Prevalence of methicillin-resistant Staphylococcus aureus among staff and pets in a small animal referral hospital in the UK. , 2005, The Journal of antimicrobial chemotherapy.

[29]  B. Bengtsson.  Swedish veterinary antimicrobial resistance monitoring (SVARM) 2008. , 2009 .