Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.
暂无分享,去创建一个
L. Sussel | D. Anderson | M. German | J. Kalamaras | D. Scheel | J. E. Lee | V. Schwitzgebel | Jeffrey D. Johnson | Jennifer R. Conners | J. Johnson | David J. Anderson | Jacqueline E. Lee | J. Conners | David W. Scheel
[1] M. Tsai,et al. Regulation of the Pancreatic Islet-Specific GeneBETA2 (neuroD) by Neurogenin 3 , 2000, Molecular and Cellular Biology.
[2] F. Guillemot,et al. neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[3] M. Stoffel,et al. Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites. , 2000, The Journal of biological chemistry.
[4] O. Madsen,et al. Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. , 2000, Diabetes.
[5] Michael S. German,et al. Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development , 1999, Molecular and Cellular Biology.
[6] David J. Anderson,et al. Notch signalling controls pancreatic cell differentiation , 1999, Nature.
[7] P. Gruss,et al. Pancreas development and diabetes. , 1999, Current opinion in genetics & development.
[8] H. Arnold,et al. Muscle differentiation: more complexity to the network of myogenic regulators. , 1998, Current opinion in genetics & development.
[9] M S German,et al. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. , 1998, Development.
[10] O. Madsen,et al. Rat Endocrine Pancreatic Development in Relation to Two Homeobox Gene Products (Pdx-1 and Nkx 6.1) , 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[11] H. Edlund. Transcribing pancreas. , 1998, Diabetes.
[12] J. Habener,et al. POU domain transcription factor brain 4 confers pancreatic alpha-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element , 1997, Molecular and cellular biology.
[13] R. Stein,et al. Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene , 1997, Molecular and cellular biology.
[14] H. Edlund,et al. Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas , 1997, Current Biology.
[15] M. Tsai,et al. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. , 1997, Genes & development.
[16] M. German,et al. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. , 1997, Genes & development.
[17] F. Guillemot,et al. Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. , 1997, Development.
[18] P. Gruss,et al. The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas , 1997, Nature.
[19] Jacqueline E. Lee. Basic helix-loop-helix genes in neural development , 1997, Current Opinion in Neurobiology.
[20] G. Lyons,et al. Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. , 1997, Developmental biology.
[21] Samuel L. Pfaff,et al. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells , 1997, Nature.
[22] R. Kageyama,et al. Conversion of ectoderm into a neural fate by ATH‐3, a vertebrate basic helix–loop–helix gene homologous to Drosophila proneural gene atonal , 1997, The EMBO journal.
[23] P Gruss,et al. Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas. , 1997, Nature.
[24] F. Guillemot,et al. Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors. , 1996, Developmental biology.
[25] David J. Anderson,et al. Identification of neurogenin, a Vertebrate Neuronal Determination Gene , 1996, Cell.
[26] David J. Anderson,et al. neurogenins,a Novel Family ofatonal-Related bHLH Transcription Factors, Are Putative Mammalian Neuronal Determination Genes That Reveal Progenitor Cell Heterogeneity in the Developing CNS and PNS , 1996, Molecular and Cellular Neuroscience.
[27] S. Tapscott,et al. NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family , 1996, Molecular and cellular biology.
[28] E. Olson,et al. Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[29] O. Madsen,et al. mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor* , 1996, The Journal of Biological Chemistry.
[30] B. Hogan,et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. , 1996, Development.
[31] P. Sawchenko,et al. Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2. , 1995, Genes & development.
[32] R. Balling,et al. Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. , 1995, Developmental biology.
[33] W. Rutter,et al. Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[34] J. Slack. Developmental biology of the pancreas. , 1995, Development.
[35] H. Weintraub,et al. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. , 1995, Science.
[36] M. Tsai,et al. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. , 1995, Genes & development.
[37] G. Lyons,et al. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. , 1995, Development.
[38] R. Stein,et al. Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. , 1995, Development.
[39] L. Orci,et al. Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[40] W. Rutter,et al. Pancreatic beta cells express a diverse set of homeobox genes. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[41] D. Hanahan,et al. Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans. , 1994, The American journal of pathology.
[42] F. Radvanyi,et al. Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells. , 1994, Molecular endocrinology.
[43] A. Leiter,et al. Expression of peptide YY in all four islet cell types in the developing mouse pancreas suggests a common peptide YY-producing progenitor. , 1994, Development.
[44] Y. Jan,et al. HLH proteins, fly neurogenesis, and vertebrate myogenesis , 1993, Cell.
[45] David J. Anderson,et al. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons , 1993, Cell.
[46] H. Ohlsson,et al. IPF1, a homeodomain‐containing transactivator of the insulin gene. , 1993, The EMBO journal.
[47] D. Hanahan,et al. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. , 1993, Development.
[48] W. Rutter,et al. Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. , 1992, Genes & development.
[49] W. Rutter,et al. Onset of cell-specific gene expression in the developing mouse pancreas. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[50] L. Orci,et al. Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. , 1991, Development.
[51] T. Saito,et al. Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. , 1991, Genes & development.
[52] David J. Anderson,et al. Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors , 1990, Nature.
[53] K. Hamaguchi,et al. Comparison of Cytokine Effects on Mouse Pancreatic α-Cell and β-Cell Lines Viability, Secretory Function, and MHC Antigen Expression , 1990, Diabetes.
[54] G. Lyons,et al. Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis , 1989, Nature.
[55] G. Gabbiani,et al. α-Smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles , 1988 .
[56] D. Hanahan,et al. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[57] S. Githens. The pancreatic duct cell: proliferative capabilities, specific characteristics, metaplasia, isolation, and culture. , 1988, Journal of pediatric gastroenterology and nutrition.
[58] D. Hanahan,et al. Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons , 1988, Cell.
[59] G. Gabbiani,et al. Alpha-smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. , 1988, Differentiation; research in biological diversity.
[60] H. Weintraub,et al. Expression of a single transfected cDNA converts fibroblasts to myoblasts , 1987, Cell.
[61] G. Teitelman,et al. Cell lineage analysis of pancreatic islet development: glucagon and insulin cells arise from catecholaminergic precursors present in the pancreatic duct. , 1987, Developmental biology.
[62] T. Schiebler. [The biology of the pancreas]. , 1987, Verhandlungen der Deutschen Gesellschaft fur Pathologie.
[63] R. Hammer,et al. Elastase I promoter directs expression of human growth hormone and SV40 T antigen genes to pancreatic acinar cells in transgenic mice. , 1985, Cold Spring Harbor symposia on quantitative biology.
[64] W. Rutter,et al. Early differentiation of glucagon-producing cells in embryonic pancreas: a possible developmental role for glucagon. , 1973, Proceedings of the National Academy of Sciences of the United States of America.
[65] R H Williams,et al. An ultrastructural analysis of the developing embryonic pancreas. , 1972, Developmental biology.