An MRI-powered and controlled actuator technology for tetherless robotic interventions

This paper presents a novel actuation technology for robotically assisted MRI-guided interventional procedures. In the proposed approach, the MRI scanner is used to deliver power, estimate actuator state and perform closed-loop control. The actuators themselves are compact, inexpensive and wireless. Using needle driving as an example application, actuation principles and force production capabilities are examined. Actuator stability and performance are analyzed for the two cases of state estimation at the input versus the output of the actuator transmission. Closed-loop needle position control is achieved by interleaving imaging pulse sequences to estimate needle position (transmission output estimation) and propulsion pulse sequences to drive the actuator. A prototype needle driving robot is used to validate the proposed approach in a clinical MRI scanner.

[1]  Peter Kazanzides,et al.  Robotic needle guide for prostate brachytherapy: clinical testing of feasibility and performance. , 2011, Brachytherapy.

[2]  J.M. Santos,et al.  Flexible real-time magnetic resonance imaging framework , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[3]  Robert Trampel,et al.  Navigation concepts for MR image‐guided interventions , 2008, Journal of magnetic resonance imaging : JMRI.

[4]  Nobuhiko Hata,et al.  MR Compatible Surgical Assist Robot: System Integration and Preliminary Feasibility Study , 2000, MICCAI.

[5]  Antoine Ferreira,et al.  Adaptive backstepping and MEMS force sensor for an MRI-guided microrobot in the vasculature , 2011, 2011 IEEE International Conference on Robotics and Automation.

[6]  D. Caleb Rucker,et al.  A MRI-guided concentric tube continuum robot with piezoelectric actuation: A feasibility study , 2012, 2012 IEEE International Conference on Robotics and Automation.

[7]  Richard B. Miles,et al.  Effects of a Conducting Sphere Moving Through a Gradient Magnetic Field , 2010 .

[8]  Gilles Beaudoin,et al.  In Vivo MR-Tracking Based on Magnetic Signature Selective Excitation , 2008, IEEE Transactions on Medical Imaging.

[9]  Robert Trampel,et al.  Method for automatic localization of MR‐visible markers using morphological image processing and conventional pulse sequences: Feasibility for image‐guided procedures , 2007, Journal of magnetic resonance imaging : JMRI.

[10]  M. Moche,et al.  Simultaneous 3D localization of multiple MR-visible markers in fully reconstructed MR images: proof-of-concept for subsecond position tracking. , 2012, Magnetic Resonance Imaging.

[11]  Sylvain Martel,et al.  MRI-based Medical Nanorobotic Platform for the Control of Magnetic Nanoparticles and Flagellated Bacteria for Target Interventions in Human Capillaries , 2009, Int. J. Robotics Res..

[12]  Dan Stoianovici,et al.  Automatic Brachytherapy Seed Placement Under MRI Guidance , 2007, IEEE Transactions on Biomedical Engineering.

[13]  S. Martel,et al.  Automatic navigation of an untethered device in the artery of a living animal using a conventional clinical magnetic resonance imaging system , 2007 .

[14]  Constantinos Mavroidis,et al.  Magnetic resonance-compatible robotic and mechatronics systems for image-guided interventions and rehabilitation: a review study. , 2007, Annual review of biomedical engineering.

[15]  Pierre E. Dupont,et al.  Tracking and position control of an MRI-powered needle-insertion robot , 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[16]  Pierre E. Dupont,et al.  Closed-loop commutation control of an MRI-powered robot actuator , 2013, 2013 IEEE International Conference on Robotics and Automation.

[17]  J. Lewin Interventional MR imaging: concepts, systems, and applications in neuroradiology. , 1999, AJNR. American journal of neuroradiology.

[18]  Kiyoyuki Chinzei,et al.  Needle Force Sensor, Robust and Sensitive Detection of the Instant of Needle Puncture , 2004, MICCAI.

[19]  Pierre E. Dupont,et al.  Motion planning for multiple millimeter-scale magnetic capsules in a fluid environment , 2012, 2012 IEEE International Conference on Robotics and Automation.

[20]  Ming Li,et al.  Pneumatic Actuated Robotic Assistant System for Aortic Valve Replacement Under MRI Guidance , 2011, IEEE Transactions on Biomedical Engineering.

[21]  H Iseki,et al.  Development of an MRI-compatible needle insertion manipulator for stereotactic neurosurgery. , 1995, Journal of image guided surgery.

[22]  Nikolaos V Tsekos,et al.  A prototype manipulator for magnetic resonance-guided interventions inside standard cylindrical magnetic resonance imaging scanners. , 2005, Journal of biomechanical engineering.

[23]  Sylvain Martel,et al.  Adapting the clinical MRI software environment for real‐time navigation of an endovascular untethered ferromagnetic bead for future endovascular interventions , 2008, Magnetic resonance in medicine.

[24]  Gabor Fichtinger,et al.  MRI Compatibility of Robot Actuation Techniques - A Comparative Study , 2008, MICCAI.

[25]  Zion Tsz Ho Tse,et al.  Prospective motion correction using tracking coils , 2013, Magnetic resonance in medicine.

[26]  S Y Lee,et al.  Gradient waveform synthesis for magnetic propulsion using MRI gradient coils. , 2008, Physics in medicine and biology.

[27]  Wolfhard Semmler,et al.  Real-time MR navigation and localization of an intravascular catheter with ferromagnetic components , 2010, Magnetic Resonance Materials in Physics, Biology and Medicine.

[28]  Julien Cohen-Adad,et al.  In Vivo Human Brain Measurements of Axon Diameter Distributions in the Corpus Callosum using 300 mT / m Maximum Gradient Strengths , 2011 .

[29]  T. Podder,et al.  In vivo motion and force measurement of surgical needle intervention during prostate brachytherapy. , 2006, Medical physics.

[30]  Luc Soler,et al.  IN VIVO STUDY OF FORCES DURING NEEDLE INSERTIONS , 2004 .

[31]  Jake J. Abbott,et al.  Modeling Magnetic Torque and Force for Controlled Manipulation of Soft-Magnetic Bodies , 2007, IEEE Transactions on Robotics.

[32]  Kemal Tuncali,et al.  Preclinical evaluation of an MRI-compatible pneumatic robot for angulated needle placement in transperineal prostate interventions , 2012, International Journal of Computer Assisted Radiology and Surgery.

[33]  Lei Qin MRI-powered actuators for robotic interventions , 2012 .

[34]  Max A. Viergever,et al.  Localization of intravascular devices with paramagnetic markers in MR images , 2001, IEEE Transactions on Medical Imaging.