microRNA-200a downregulation in human glioma leads to Gαi1 over-expression, Akt activation, and cell proliferation
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Zheng-quan Yu | Long Cheng | C. Cao | Zhi-qing Zhang | Yuan-yuan Liu | Gang Chen | Min-bin Chen | Qin Jiang
[1] Bo Yang,et al. Gαi3 nuclear translocation causes irradiation resistance in human glioma cells , 2017, Oncotarget.
[2] H. Yi,et al. miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone , 2016, Oncotarget.
[3] Q. Jiang,et al. SC79 protects retinal pigment epithelium cells from UV radiation via activating Akt-Nrf2 signaling , 2016, Oncotarget.
[4] Su-qing Yang,et al. 3H-1,2-dithiole-3-thione protects retinal pigment epithelium cells against Ultra-violet radiation via activation of Akt-mTORC1-dependent Nrf2-HO-1 signaling , 2016, Scientific Reports.
[5] Liu Cao,et al. PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma , 2016, Oncotarget.
[6] Qing Xu,et al. Methylseleninic acid activates Keap1/Nrf2 pathway via up-regulating miR-200a in human oesophageal squamous cell carcinoma cells , 2015, Bioscience reports.
[7] Yuyuan Han,et al. Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1 , 2015, Proceedings of the National Academy of Sciences.
[8] S. Cai,et al. Over-expression of Gαi3 in human glioma is required for Akt-mTOR activation and cell growth , 2014 .
[9] M. Kool,et al. The G-protein Alpha Subunit Gsα Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma , 2014, Nature Medicine.
[10] Jin Yao,et al. Salvianolic acid A protects RPE cells against oxidative stress through activation of Nrf2/HO-1 signaling. , 2014, Free radical biology & medicine.
[11] L. Birnbaumer,et al. Giα proteins exhibit functional differences in the activation of ERK1/2, Akt and mTORC1 by growth factors in normal and breast cancer cells , 2014, Cell Communication and Signaling.
[12] Tao Jiang,et al. Understanding high grade glioma: molecular mechanism, therapy and comprehensive management. , 2013, Cancer letters.
[13] M. Rioult-Pedotti,et al. Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome , 2013, PLoS biology.
[14] Aaron S. Gajadhar,et al. Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients. , 2012, The Journal of clinical investigation.
[15] Rebecca A Betensky,et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. , 2011, Cancer cell.
[16] Manfred Westphal,et al. The neurobiology of gliomas: from cell biology to the development of therapeutic approaches , 2011, Nature Reviews Neuroscience.
[17] G. Velasco,et al. The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK , 2011, Oncogene.
[18] I. Pollack. Neuro-oncology: Therapeutic benefits of reirradiation for recurrent brain tumors , 2010, Nature Reviews Neurology.
[19] P. Majumder,et al. MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo , 2010, Molecular Cancer Therapeutics.
[20] A. Lassman,et al. Neuro-oncology: Late neurocognitive decline after radiotherapy for low-grade glioma , 2009, Nature Reviews Neurology.
[21] T. Cloughesy,et al. Targeted therapy for malignant glioma patients: Lessons learned and the road ahead , 2009, Neurotherapeutics.
[22] G. McKhann,et al. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease , 2008, Nature Medicine.
[23] Keith L. Ligon,et al. Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies , 2007, Science.
[24] R. Ozols,et al. RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model , 2007, Clinical Cancer Research.
[25] D. Sabatini. mTOR and cancer: insights into a complex relationship , 2006, Nature Reviews Cancer.
[26] K. Nikolich,et al. GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion , 2005, Oncogene.
[27] M. Mareel,et al. Suppression of Cellular Invasion by Activated G-Protein Subunits Gαo, Gαi1, Gαi2, and Gαi3 and Sequestration of Gβγ , 2001 .
[28] Thomas D. Schmittgen,et al. Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR. , 2000, Journal of biochemical and biophysical methods.
[29] P. Cohen,et al. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα , 1997, Current Biology.
[30] G. Hager,et al. Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus , 1981, Cell.
[31] K. Shulman,et al. Cyclic AMP and adenyl cyclase in brain tumors. , 1977, Journal of neurosurgery.
[32] Q. Jiang,et al. Requirement of Gαi1/3-Gab1 signaling complex for keratinocyte growth factor-induced PI3K-AKT-mTORC1 activation. , 2015, The Journal of investigative dermatology.
[33] Wei Zhang,et al. The anti-ovarian cancer activity by WYE-132, a mTORC1/2 dual inhibitor , 2015, Tumor Biology.
[34] A. Jemal,et al. Cancer statistics, 2014 , 2014, CA: a cancer journal for clinicians.
[35] A. Jemal,et al. Cancer statistics, 2012 , 2012, CA: a cancer journal for clinicians.
[36] H. Lo. EGFR-targeted therapy in malignant glioma: novel aspects and mechanisms of drug resistance. , 2010, Current molecular pharmacology.
[37] R. Kiss,et al. Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. , 2009, Advances and technical standards in neurosurgery.
[38] M. Wolter,et al. Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. , 1998, Cancer research.