Counteracting Activities of OCT4 and KLF4 during Reprogramming to Pluripotency

[1]  A. Schnerch,et al.  Author Correction: Direct conversion of human fibroblasts to multilineage blood progenitors , 2018, Nature.

[2]  M. Araúzo-Bravo,et al.  Sox2 Level Is a Determinant of Cellular Reprogramming Potential , 2013, PloS one.

[3]  P. Verma,et al.  The Effects of Nuclear Reprogramming on Mitochondrial DNA Replication , 2013, Stem Cell Reviews and Reports.

[4]  Jeroen Krijgsveld,et al.  Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. , 2012, Cell reports.

[5]  S. Ramaswamy,et al.  A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells , 2012, Cell.

[6]  M. Araúzo-Bravo,et al.  Correction: Corrigendum: Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins , 2012, Nature Communications.

[7]  Greg Donahue,et al.  Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome , 2012, Cell.

[8]  Sandy L. Klemm,et al.  Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase , 2012, Cell.

[9]  M. Nöthen,et al.  Direct conversion of fibroblasts into stably expandable neural stem cells. , 2012, Cell stem cell.

[10]  Dong Wook Han,et al.  Direct reprogramming of fibroblasts into neural stem cells by defined factors. , 2012, Cell stem cell.

[11]  G. Pan,et al.  The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. , 2011, Cell stem cell.

[12]  Andre Terzic,et al.  Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. , 2011, Cell metabolism.

[13]  Stuart H. Orkin,et al.  Chromatin Connections to Pluripotency and Cellular Reprogramming , 2011, Cell.

[14]  H. Schöler,et al.  Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells , 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[15]  S. S. Zhang,et al.  A mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorder , 2011, Molecular Biology Reports.

[16]  S. Lipton,et al.  Direct reprogramming of mouse fibroblasts to neural progenitors , 2011, Proceedings of the National Academy of Sciences.

[17]  Gang Wang,et al.  Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy , 2011, Nature Cell Biology.

[18]  Zachary D. Smith,et al.  Reprogramming factor expression initiates widespread targeted chromatin remodeling. , 2011, Cell stem cell.

[19]  M. Araúzo-Bravo,et al.  Epiblast Stem Cell Subpopulations Represent Mouse Embryos of Distinct Pregastrulation Stages , 2010, Cell.

[20]  V. Vedantham,et al.  Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors , 2010, Cell.

[21]  Thomas Vierbuchen,et al.  Direct conversion of fibroblasts to functional neurons by defined factors , 2010, Nature.

[22]  David R. Liu,et al.  A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. , 2009, Cell stem cell.

[23]  K. Hochedlinger,et al.  Tgfβ Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc , 2009, Current Biology.

[24]  Jeroen S. van Zon,et al.  Direct cell reprogramming is a stochastic process amenable to acceleration , 2009, Nature.

[25]  J. Hennebold,et al.  Expression of ovary-specific acidic protein in steroidogenic tissues: a possible role in steroidogenesis. , 2009, Endocrinology.

[26]  H. Federoff,et al.  HUMMR, a hypoxia- and HIF-1α–inducible protein, alters mitochondrial distribution and transport , 2009, The Journal of cell biology.

[27]  Mike J. Mason,et al.  Role of the Murine Reprogramming Factors in the Induction of Pluripotency , 2009, Cell.

[28]  Thomas Lufkin,et al.  Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb , 2009, Nature Cell Biology.

[29]  Alice T. Loo,et al.  PTEN-deficient cancers depend on PIK3CB , 2008, Proceedings of the National Academy of Sciences.

[30]  D. Gifford,et al.  Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET , 2008, Genome Biology.

[31]  M. Araúzo-Bravo,et al.  Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors , 2008, Nature.

[32]  N. D. Clarke,et al.  Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells , 2008, Cell.

[33]  K. Hochedlinger,et al.  Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. , 2008, Cell stem cell.

[34]  Sheng Zhong,et al.  A core Klf circuitry regulates self-renewal of embryonic stem cells , 2008, Nature Cell Biology.

[35]  C. Lengner,et al.  Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells. , 2008, Cell stem cell.

[36]  Alexei A. Sharov,et al.  Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells , 2007, Nature Cell Biology.

[37]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[38]  T. Hamamoto,et al.  Distribution of CESP-1 protein in the corneal endothelium and other tissues. , 2006, Investigative ophthalmology & visual science.

[39]  Megan F. Cole,et al.  Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.

[40]  Austin G Smith,et al.  Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell , 2005, PLoS biology.

[41]  P. Robson,et al.  Transcriptional Regulation of Nanog by OCT4 and SOX2* , 2005, Journal of Biological Chemistry.

[42]  Rudolf Jaenisch,et al.  Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues , 2005, Cell.

[43]  M. Wiznerowicz,et al.  Conditional Suppression of Cellular Genes: Lentivirus Vector-Mediated Drug-Inducible RNA Interference , 2003, Journal of Virology.

[44]  Matthias Wilmanns,et al.  Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. , 2003, Genes & development.

[45]  N. Daigle,et al.  A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture. , 2002, Gene.

[46]  J. Miyazaki,et al.  Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells , 2000, Nature Genetics.

[47]  H. Schöler,et al.  Germline‐specific expression of the Oct‐4/green fluorescent protein (GFP) transgene in mice , 1999, Development, growth & differentiation.

[48]  H. Schöler,et al.  Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 , 1998, Cell.

[49]  M. Araúzo-Bravo,et al.  Direct reprogramming of fibroblasts into epiblast stem cells , 2011, Nature Cell Biology.

[50]  M. Araúzo-Bravo,et al.  Identification of genes specific to mouse primordial germ cells through dynamic global gene expression. , 2011, Human molecular genetics.

[51]  Takashi Aoi,et al.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.

[52]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.