A silyl andrographolide analogue suppresses Wnt/β-catenin signaling pathway in colon cancer.
暂无分享,去创建一个
Weiming Zhu | A. Chairoungdua | R. Saeeng | Somrudee Reabroi | P. Piyachaturawat | W. Saengsawang | T. Kasemsuk
[1] E. Beltrão,et al. DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents? , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[2] Mintu Pal,et al. Predictive and prognostic biomarkers in colorectal cancer: A systematic review of recent advances and challenges. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[3] S. Czinn,et al. Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells , 2017, Oncotarget.
[4] P. Tuchinda,et al. 5-Acetyl goniothalamin suppresses proliferation of breast cancer cells via Wnt/β-catenin signaling. , 2016, European journal of pharmacology.
[5] S. Czinn,et al. Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment , 2016, Oncotarget.
[6] F. Valeriote,et al. Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer , 2016, Oncogene.
[7] J. Stanslas,et al. SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells , 2014, Cell Biology and Toxicology.
[8] S. Dutta,et al. Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition. , 2014, European journal of pharmacology.
[9] S. Dutta,et al. Inhibition of topoisomerase II α activity and induction of apoptosis in mammalian cells by semi-synthetic andrographolide analogues , 2013, Investigational New Drugs.
[10] R. Moon,et al. WNT signalling pathways as therapeutic targets in cancer , 2012, Nature Reviews Cancer.
[11] K. Suksen,et al. A Phytoestrogen Diarylheptanoid Mediates Estrogen Receptor/Akt/Glycogen Synthase Kinase 3β Protein-dependent Activation of the Wnt/β-Catenin Signaling Pathway* , 2012, The Journal of Biological Chemistry.
[12] Hans Clevers,et al. Wnt/β-Catenin Signaling and Disease , 2012, Cell.
[13] S. Sieber,et al. Electrophilic natural products and their biological targets. , 2012, Natural product reports.
[14] Yolanda Fernández,et al. β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer , 2012, Nature Medicine.
[15] Paul Polakis,et al. Wnt signaling in cancer. , 2012, Cold Spring Harbor perspectives in biology.
[16] J. Stanslas,et al. Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer , 2012, Clinical and experimental pharmacology & physiology.
[17] B. Schmidt,et al. All tangled up: how cells direct, manage and exploit topoisomerase function , 2011, Nature Reviews Molecular Cell Biology.
[18] Juan Zhou,et al. Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein. , 2011, Journal of pharmaceutical sciences.
[19] M. Chatterjee,et al. Synthesis, cytotoxicity, and structure-activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent. , 2010, Bioorganic & medicinal chemistry letters.
[20] Jingsong Yuan,et al. Focus on histone variant H2AX: To be or not to be , 2010, FEBS letters.
[21] S. Kaufmann,et al. PARP inhibition: PARP1 and beyond , 2010, Nature Reviews Cancer.
[22] Marc W. Kirschner,et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling , 2009, Nature.
[23] J. Nitiss. Targeting DNA topoisomerase II in cancer chemotherapy , 2009, Nature Reviews Cancer.
[24] A. Lazaris,et al. Topoisomerase I and IIα protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy , 2008, Cancer Chemotherapy and Pharmacology.
[25] M. Stevens,et al. Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis , 2008, British journal of pharmacology.
[26] W. Birchmeier,et al. Wnt signalling and its impact on development and cancer , 2008, Nature Reviews Cancer.
[27] Chika Yokota,et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions , 2007, Development.
[28] S. Hirohashi,et al. Functional Interaction of DNA Topoisomerase IIα With the β-Catenin and T-Cell Factor-4 Complex , 2007 .
[29] M. Stevens,et al. Semisynthesis and in vitro anticancer activities of andrographolide analogues. , 2007, Phytochemistry.
[30] J. M. Babu,et al. Synthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agents. , 2004, Bioorganic & medicinal chemistry letters.
[31] B. Boman,et al. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. , 2001, Cancer research.
[32] H. Wagner,et al. Pharmacokinetic and oral bioavailability of andrographolide from Andrographis paniculata fixed combination Kan Jang in rats and human. , 2000, Phytomedicine : international journal of phytotherapy and phytopharmacology.
[33] Randall T Moon,et al. Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways , 1999, Oncogene.
[34] C. Albanese,et al. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[35] Paul Polakis,et al. The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors , 1999, Oncogene.
[36] A. Sparks,et al. Identification of c-MYC as a target of the APC pathway. , 1998, Science.
[37] Hans Clevers,et al. Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC , 1997, Science.
[38] K. Kinzler,et al. Lessons from Hereditary Colorectal Cancer , 1996, Cell.
[39] K. Suksen,et al. New substituted C-19-andrographolide analogues with potent cytotoxic activities. , 2012, Bioorganic & medicinal chemistry letters.