Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells
暂无分享,去创建一个
D. Green | D. Stolz | F. Llambi | Jingnan Wang | V. Roginskaya | B. V. Houten | R. Edwards | W. Qian | L. Mcdermott | R. Edwards
[1] Richard G. Moore,et al. A prospective study evaluating the clinical relevance of a chemoresponse assay for treatment of patients with persistent or recurrent ovarian cancer. , 2013, Gynecologic oncology.
[2] S. Archer,et al. Role of Dynamin-Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen Sensing and Constriction of the Ductus Arteriosus , 2013, Circulation research.
[3] M. Oren,et al. Cisplatin hypersensitivity of testicular germ cell tumors is determined by high constitutive Noxa levels mediated by Oct-4. , 2013, Cancer research.
[4] Simon C Watkins,et al. Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress , 2012, Journal of Cell Science.
[5] Yuquan Wei,et al. NOXA-Induced Alterations in the Bax/Smac Axis Enhance Sensitivity of Ovarian Cancer Cells to Cisplatin , 2012, PloS one.
[6] L. Galluzzi,et al. Molecular mechanisms of cisplatin resistance , 2012, Oncogene.
[7] R. Bast,et al. Minireview: human ovarian cancer: biology, current management, and paths to personalizing therapy. , 2012, Endocrinology.
[8] J. Richards,et al. Minireview: animal models and mechanisms of ovarian cancer development. , 2012, Endocrinology.
[9] R. Youle,et al. Predominant requirement of Bax for apoptosis in HCT116 cells is determined by Mcl-1’s inhibitory effect on Bak , 2011, Oncogene.
[10] J. Levine,et al. Role of Drp1, a Key Mitochondrial Fission Protein, in Neuropathic Pain , 2011, The Journal of Neuroscience.
[11] P. Reaper,et al. Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR. , 2011, Nature chemical biology.
[12] Sang Woo Park,et al. A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. , 2011, Investigative ophthalmology & visual science.
[13] F. Spinella,et al. Acquisition of Chemoresistance and EMT Phenotype Is Linked with Activation of the Endothelin A Receptor Pathway in Ovarian Carcinoma Cells , 2011, Clinical Cancer Research.
[14] G. Brumatti,et al. An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs , 2010, Oncogene.
[15] B. Van Houten,et al. Alterations in bioenergetics due to changes in mitochondrial DNA copy number. , 2010, Methods.
[16] J. Nunnari,et al. Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine. , 2010, Chemistry & biology.
[17] T. Chou. Drug combination studies and their synergy quantification using the Chou-Talalay method. , 2010, Cancer research.
[18] Z. Dong,et al. Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. , 2009, The Journal of clinical investigation.
[19] R. Kofler,et al. Noxa: at the tip of the balance between life and death , 2008, Oncogene.
[20] P. Borst,et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs , 2008, Proceedings of the National Academy of Sciences.
[21] T. Kuwana,et al. Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. , 2008, Developmental cell.
[22] M. Nachtigal,et al. Primary culture of ovarian surface epithelial cells and ascites-derived ovarian cancer cells from patients , 2006, Nature Protocols.
[23] R. Burger,et al. Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study , 2005, BMJ : British Medical Journal.
[24] Dong Wang,et al. Cellular processing of platinum anticancer drugs , 2005, Nature Reviews Drug Discovery.
[25] I. Herskowitz,et al. Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[26] Y. Pommier,et al. Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells. , 2002, Cancer research.
[27] E. Alnemri,et al. Abrogation of Mitochondrial Cytochrome c Release and Caspase-3 Activation in Acquired Multidrug Resistance* , 1998, The Journal of Biological Chemistry.
[28] B. van de Water,et al. Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain. , 1997, The Journal of pharmacology and experimental therapeutics.
[29] G. Chu,et al. Cellular responses to cisplatin. The roles of DNA-binding proteins and DNA repair. , 1994, The Journal of biological chemistry.
[30] C. Runowicz. Advances in the screening and treatment of ovarian cancer , 1992, CA: a cancer journal for clinicians.
[31] A. Pa,et al. Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. , 1990 .
[32] J. Mcvie,et al. Direct diffusion of cis-diamminedichloroplatinum(II) in intraperitoneal rat tumors after intraperitoneal chemotherapy: a comparison with systemic chemotherapy. , 1989, Cancer research.
[33] C. Sorenson,et al. Influence of cis-diamminedichloroplatinum(II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient Chinese hamster ovary cells. , 1988, Cancer research.
[34] Yun Feng,et al. PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expression. , 2011, Cancer letters.
[35] Lorenzo Galluzzi,et al. Mitochondrial membrane permeabilization in cell death. , 2007, Physiological reviews.
[36] Kaori Sasai,et al. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53 , 2004, Nature Genetics.
[37] S. Howell,et al. Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. , 1990, Cancer cells.
[38] A. Eastman. The formation, isolation and characterization of DNA adducts produced by anticancer platinum complexes. , 1987, Pharmacology & therapeutics.