Effects of Transcendental Meditation practice on brain functioning and stress reactivity in college students.

This randomized controlled trial investigated effects of Transcendental Meditation (TM) practice on Brain Integration Scale scores (broadband frontal coherence, power ratios, and preparatory brain responses), electrodermal habituation to 85-dB tones, sleepiness, heart rate, respiratory sinus arrhythmia, and P300 latencies in 50 college students. After pretest, students were randomly assigned to learn TM immediately or learn after the 10-week posttest. There were no significant pretest group differences. A MANOVA of students with complete data (N=38) yielded significant group vs treatment interactions for Brain Integration Scale scores, sleepiness, and habituation rates (all p<.007). Post hoc analyses revealed significant increases in Brain Integration Scale scores for Immediate-start students but decreases in Delayed-start students; significant reductions in sleepiness in Immediate-start students with no change in Delayed-start students; and no changes in habituation rates in Immediate-start students, but significant increases in Delayed-start students. These data support the value of TM practice for college students.

[1]  J. Donoghue.  Plasticity of adult sensorimotor representations , 1995, Current Opinion in Neurobiology.

[2]  D. Orme-Johnson,et al.  Physiological differences between transcendental meditation and rest. , 1987 .

[3]  E. Toft,et al.  C‐Reactive Protein Is Associated with Heart Rate Variability , 2007, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[4]  J. Dwyer,et al.  Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease. , 2006, Archives of internal medicine.

[5]  B. McEwen.  Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load. , 2006, Metabolism: clinical and experimental.

[6]  F. Travis,et al.  A second linked-reference issue: possible biasing of power and coherence spectra. , 1994, The International journal of neuroscience.

[7]  P. Venables,et al.  Publication recommendations for electrodermal measurements. , 1981 .

[8]  G Fein,et al.  Common reference coherence data are confounded by power and phase effects. , 1988, Electroencephalography and clinical neurophysiology.

[9]  John V. Carlis,et al.  Where the brain grows old: Decline in anterior cingulate and medial prefrontal function with normal aging , 2007, NeuroImage.

[10]  R. Thatcher,et al.  Cortico-cortical associations and EEG coherence: a two-compartmental model. , 1986, Electroencephalography and clinical neurophysiology.

[11]  M. Johns,et al.  Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth sleepiness scale: Failure of the MSLT as a gold standard , 2000, Journal of sleep research.

[12]  Walter C. Buboltz,et al.  Sleep Habits and Patterns of College Students: A Preliminary Study , 2001, Journal of American college health : J of ACH.

[13]  D. Orme-Johnson.  Autonomic Stability and Transcendental Meditation , 1973, Psychosomatic medicine.

[14]  Satoshi Mochizuki,et al.  Learning-related changes of brain activation in the visual ventral stream: An fMRI study of mirror reading skill , 2006, Brain Research.

[15]  Examination , 1947 .

[16]  Bruce Mcewen,et al.  Stress, Adaptation, and Disease: Allostasis and Allostatic Load , 1998, Annals of the New York Academy of Sciences.

[17]  H. Nagaraja,et al.  Heart rate variability: origins, methods, and interpretive caveats. , 1997, Psychophysiology.

[18]  M. Dillbeck,et al.  Meditation and flexibility of visual perception and verbal problem solving , 1982, Memory & cognition.

[19]  Zang-Hee Cho,et al.  Neuroimaging of meditation's effect on brain reactivity to pain , 2006, Neuroreport.

[20]  M. V. Senden,et al.  Space and Sight , 1962 .

[21]  Frederick Travis,et al.  Psychological and physiological characteristics of a proposed object-referral/self-referral continuum of self-awareness , 2004, Consciousness and Cognition.

[22]  Thomas G. Plante,et al.  Meditation Lowers Stress and Supports Forgiveness Among College Students: A Randomized Controlled Trial , 2008, Journal of American college health : J of ACH.

[23]  R. N. Caine,et al.  Making Connections: Teaching and the Human Brain , 1991 .

[24]  F. Travis,et al.  Cortical plasticity, contingent negative variation, and transcendent experiences during practice of the Transcendental Meditation technique , 2000, Biological Psychology.

[25]  R. Chervin.  The multiple sleep latency test and Epworth sleepiness scale in the assessment of daytime sleepiness , 2000, Journal of sleep research.

[26]  J. Gackenbach,et al.  Transcendental meditation and improved performance on intelligence-related measures: A longitudinal study , 1991 .

[27]  P. Grossman,et al.  Prediction of tonic parasympathetic cardiac control using respiratory sinus arrhythmia: the need for respiratory control. , 1991, Psychophysiology.

[28]  C. Carter,et al.  Anterior cingulate cortex and conflict detection: An update of theory and data , 2007, Cognitive, affective & behavioral neuroscience.

[29]  Carlos M. Gómez,et al.  Fronto-parietal networks activation during the contingent negative variation period , 2007, Brain Research Bulletin.

[30]  J. Polich,et al.  Meditation states and traits: EEG, ERP, and neuroimaging studies. , 2006, Psychological bulletin.

[31]  M. Cole,et al.  Correlations among Epworth Sleepiness Scale scores, multiple sleep latency tests and psychological symptoms , 1998, Journal of sleep research.

[32]  D. Buonomano,et al.  Cortical plasticity: from synapses to maps. , 1998, Annual review of neuroscience.

[33]  E. Mascha,et al.  Association between the Epworth Sleepiness Scale and the Multiple Sleep Latency Test in a Clinical Population , 1999, Annals of Internal Medicine.

[34]  Kam-Tim So,et al.  Three randomized experiments on the longitudinal effects of the Transcendental Meditation technique on cognition , 2001 .

[35]  D. Hubel,et al.  Ferrier lecture - Functional architecture of macaque monkey visual cortex , 1977, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[36]  D. Berger,et al.  Examination stress as an ecological inducer of cortisol and psychological responses to stress in undergraduate students , 2006, Stress.

[37]  H. Myers,et al.  Effects of stress reduction on carotid atherosclerosis in hypertensive African Americans. , 2000, Stroke.

[38]  Frederick Travis,et al.  CROSS-SECTIONAL AND LONGITUDINAL STUDY OF EFFECTS OF TRANSCENDENTAL MEDITATION PRACTICE ON INTERHEMISPHERIC FRONTAL ASYMMETRY AND FRONTAL COHERENCE , 2006, The International journal of neuroscience.

[39]  K. Eppley,et al.  Differential effects of relaxation techniques on trait anxiety: a meta-analysis. , 1989, Journal of clinical psychology.

[40]  B. Rockstroh,et al.  Increased Cortical Representation of the Fingers of the Left Hand in String Players , 1995, Science.

[41]  E. Maguire,et al.  London taxi drivers and bus drivers: A structural MRI and neuropsychological analysis , 2006, Hippocampus.

[42]  Anne Wescott Dodd.  Unleashing the Power of Perceptual Change: The Potential of Brain-Based Teaching. By Renate Nummela Caine and Geoffrey Caine. Alexandria, Va.: Association for Supervision and Curriculum Development, 1997 , 1998 .

[43]  R. Schneider,et al.  A randomised controlled trial of stress reduction for hypertension in older African Americans. , 1995, Hypertension.

[44]  K. Hugdahl,et al.  Cortical control of human classical conditioning: autonomic and positron emission tomography data. , 1998, Psychophysiology.

[45]  H. Critchley,et al.  Neural Activity Relating to Generation and Representation of Galvanic Skin Conductance Responses: A Functional Magnetic Resonance Imaging Study , 2000, The Journal of Neuroscience.

[46]  F. Travis,et al.  Pure Consciousness: Distinct Phenomenological and Physiological Correlates of “Consciousness Itself” , 2000, The International journal of neuroscience.

[47]  William T. McKinney,et al.  Synaptic Self: How Our Brains Become Who We Are , 2002 .

[48]  B. McEwen,et al.  Protection and Damage from Acute and Chronic Stress: Allostasis and Allostatic Overload and Relevance to the Pathophysiology of Psychiatric Disorders , 2004, Annals of the New York Academy of Sciences.

[49]  R. Thatcher,et al.  Human cerebral hemispheres develop at different rates and ages. , 1987, Science.

[50]  M. Carskadon,et al.  Neurobehavioral performance of residents after heavy night call vs after alcohol ingestion. , 2005, JAMA.

[51]  Claire Wang,et al.  The neurocognitive effects of alcohol on adolescents and college students. , 2005, Preventive medicine.

[52]  F. Travis,et al.  Autonomic and EEG patterns distinguish transcending from other experiences during Transcendental Meditation practice. , 2001, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[53]  D. Orme-Johnson,et al.  The effects of the transcendental mediation technique and progressive muscle relaxation on EEG coherence, stress reactivity, and mental health in black adults. , 1989, The International journal of neuroscience.

[54]  P. Grossman,et al.  Respiratory sinus arrhythmia, cardiac vagal tone, and respiration: within- and between-individual relations. , 1993, Psychophysiology.

[55]  M. Dillbeck,et al.  Short-term longitudinal effects of the transcendental meditation technique on EEG power and coherence. , 1981, The International journal of neuroscience.

[56]  N. Risch,et al.  The continuous performance test, identical pairs version (CPT-IP): I. new findings about sustained attention in normal families , 1988, Psychiatry Research.

[57]  C. Alexander,et al.  Transcendental meditation, self-actualization, and psychological health: A conceptual overview and statistical meta-analysis. , 1991 .

[58]  P. Goddard.  Transcendental Meditation as an intervention in the aging of neurocognitive function: Reduced age-related declines of P300 latencies in elderly practitioners. , 1992 .

[59]  R. Schneider,et al.  A Randomized Controlled Trial of Stress Reduction for Hypertension in Older African Americans , 1995 .

[60]  G. Arankowsky-Sandoval,et al.  Evaluation of depressive symptoms and sleep alterations in college students. , 2005, Archives of medical research.

[61]  J. Sztajzel.  Heart rate variability: a noninvasive electrocardiographic method to measure the autonomic nervous system. , 2004, Swiss medical weekly.

[62]  M. Merzenich,et al.  Long-Term Change of Mind , 1998, Science.

[63]  Yoshihiro Kitamura,et al.  Medial Prefrontal Cortex and Anterior Cingulate Cortex in the Generation of Alpha Activity Induced by Transcendental Meditation : A Magnetoencephalographic Study , 2006 .

[64]  J. Zull.  The Art of Changing the Brain , 2023 .

[65]  F. Wilhelm,et al.  Respiratory sinus arrhythmia, cardiac vagal control, and daily activity. , 2004, American journal of physiology. Heart and circulatory physiology.

[66]  L. Kim,et al.  Cognitive deterioration and changes of P300 during total sleep deprivation , 2003, Psychiatry and clinical neurosciences.

[67]  B. McEwen.  Protective and damaging effects of stress mediators: central role of the brain , 2006, Dialogues in clinical neuroscience.

[68]  R. K. Wallace,et al.  Patterns of EEG coherence, power, and contingent negative variation characterize the integration of transcendental and waking states , 2002, Biological Psychology.

[69]  Dietrich Lehmann,et al.  Enhanced EEG alpha time-domain phase synchrony during Transcendental Meditation: Implications for cortical integration theory , 2005, Signal Process..

[70]  S. Shapiro,et al.  Cultivating mindfulness: effects on well-being. , 2008, Journal of clinical psychology.

[71]  R. Johnson,et al.  On the neural generators of the P300 component of the event-related potential. , 2007, Psychophysiology.