MicroRNA-196a/-196b regulate the progression of hepatocellular carcinoma through modulating the JAK/STAT pathway via targeting SOCS2

[1]  L. Kenner,et al.  Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression. , 2019, Cytokine.

[2]  Wei Yang,et al.  Oviductus ranae protein hydrolysate (ORPH) inhibits the growth, metastasis and glycolysis of HCC by targeting miR-491-5p/PKM2 axis. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  J. Ai,et al.  Combination therapy of sorafenib with mesenchymal stem cells as a novel cancer treatment regimen in xenograft models of hepatocellular carcinoma , 2018, Journal of cellular physiology.

[4]  Keyuan Zhou,et al.  Upregulation of miR-196b-5p attenuates BCG uptake via targeting SOCS3 and activating STAT3 in macrophages from patients with long-term cigarette smoking-related active pulmonary tuberculosis , 2018, Journal of Translational Medicine.

[5]  Hui-Xiong Xu,et al.  The Role of MicroRNAs in Hepatocellular Carcinoma , 2018, Journal of Cancer.

[6]  M. Fiorentino,et al.  Role of microRNAs in the main molecular pathways of hepatocellular carcinoma , 2018, World journal of gastroenterology.

[7]  Wei Zhang,et al.  miR-196b is a prognostic factor of human laryngeal squamous cell carcinoma and promotes tumor progression by targeting SOCS2. , 2018, Biochemical and biophysical research communications.

[8]  Lai Wei,et al.  RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2 , 2018, Hepatology.

[9]  L. Qin,et al.  Role of exosomes and exosomal microRNAs in hepatocellular carcinoma: Potential in diagnosis and antitumour treatments (Review) , 2018, International journal of molecular medicine.

[10]  M. Tian,et al.  microRNA‑196b promotes cell migration and invasion by targeting FOXP2 in hepatocellular carcinoma. , 2017, Oncology reports.

[11]  Guo-lin Zhang,et al.  6‐Hydroxy‐3‐O‐methyl‐kaempferol 6‐O‐glucopyranoside potentiates the anti‐proliferative effect of interferon &agr;/&bgr; by promoting activation of the JAK/STAT signaling by inhibiting SOCS3 in hepatocellular carcinoma cells , 2017, Toxicology and applied pharmacology.

[12]  Heping Li,et al.  Maintenance of stemness by miR-589-5p in hepatocellular carcinoma cells promotes chemoresistance via STAT3 signaling. , 2017, Cancer letters.

[13]  S. Zhang,et al.  Long Noncoding RNA HCAL Facilitates the Growth and Metastasis of Hepatocellular Carcinoma by Acting as a ceRNA of LAPTM4B , 2017, Molecular therapy. Nucleic acids.

[14]  J. Qin,et al.  Downregulation of microRNA-196a inhibits human liver cancer cell proliferation and invasion by targeting FOXO1 , 2017, Oncology reports.

[15]  Yitao Ding,et al.  Development and Validation of a Three-gene Prognostic Signature for Patients with Hepatocellular Carcinoma , 2017, Scientific Reports.

[16]  Jianguo Wu,et al.  Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action , 2017, Scientific Reports.

[17]  Hao Xu,et al.  HCV core protein-induced upregulation of microRNA-196a promotes aberrant proliferation in hepatocellular carcinoma by targeting FOXO1. , 2016, Molecular medicine reports.

[18]  J. Bruix,et al.  Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma. , 2016, Gastroenterology.

[19]  A. Cheng,et al.  miR-196, an Emerging Cancer Biomarker for Digestive Tract Cancers , 2016, Journal of Cancer.

[20]  B. Sangro,et al.  Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach-the ALBI grade. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  T. Yen,et al.  OncomiR-196 promotes an invasive phenotype in oral cancer through the NME4-JNK-TIMP1-MMP signaling pathway , 2014, Molecular Cancer.

[22]  Cheng‐Yi Chen,et al.  MicroRNA-196a/-196b promote cell metastasis via negative regulation of radixin in human gastric cancer. , 2014, Cancer letters.

[23]  P. Zhao,et al.  MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3. , 2014, Virology.

[24]  Y. Tu,et al.  Reduced expression of SOCS2 and SOCS6 in hepatocellular carcinoma correlates with aggressive tumor progression and poor prognosis , 2013, Molecular and Cellular Biochemistry.

[25]  Chien-Jen Chen,et al.  Genome-wide aberrant DNA methylation of microRNA host genes in hepatocellular carcinoma , 2012, Epigenetics.

[26]  B. Gao,et al.  STAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liver. , 2012, Journal of hepatology.

[27]  G. Sethi,et al.  γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro‐apoptotic and chemosensitizing agent , 2011, British journal of pharmacology.

[28]  Q. Yao,et al.  MicroRNA-196: critical roles and clinical applications in development and cancer , 2011, Journal of cellular and molecular medicine.

[29]  Shuang Huang,et al.  Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis. , 2010, Cancer research.

[30]  Satoshi O. Suzuki,et al.  MiRNA-196 Is Upregulated in Glioblastoma But Not in Anaplastic Astrocytoma and Has Prognostic Significance , 2010, Clinical Cancer Research.

[31]  D. Bartel.  MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[32]  A. Flores-Morales,et al.  Suppressor of cytokine signaling (SOCS) 2, a protein with multiple functions. , 2006, Cytokine & growth factor reviews.

[33]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[34]  M. Belvisi,et al.  Effects of aerobic exercise on molecular aspects of asthma: involvement of SOCS-JAK-STAT. , 2019, Exercise immunology review.

[35]  Yi-jun Wang,et al.  Analysis of microRNA expression profiles in human hepatitis B virus-related hepatocellular carcinoma. , 2013, Clinical laboratory.

[36]  C. Gonçalves,et al.  [Hepatocellular carcinoma]. , 1988, Arquivos de gastroenterologia.

[37]  D. Woodfield.  Hepatocellular carcinoma. , 1986, The New Zealand medical journal.