PIVOT : Protein Interactions VisualizatiOn Tool

Summary: PIVOT is a visualization tool for proteinprotein interactions. It allows the user to create personal datasets of interactions by combining information from private and public data sources. The user can gradually access the interactions' data using a clear interactive map that is focused on the researcher's protein of interest, and is reshaped and expanded in response to his/her queries. It also offers several visual enhancements and intelligent queries that help the user efficiently study it. PIVOT allows the user to search the interactions dataset for paths connecting proteins that are expected to cooperate. The user can also employ PIVOT to predict unknown interactions among proteins, based on interactions among their homologous proteins in other species. Availability: Freely available for academic users, at http://www.cs.tau.ac.il/~rshamir/pivot Contact: niro@post.tau.ac.il Supplementary Information: A demonstration video clip is available at http://www.cs.tau.ac.il/~rshamir/pivot/Demo.avi