Interleukin 15 augments antitumor activity of cytokine gene-modified melanoma cell vaccines in a murine model.
暂无分享,去创建一个
[1] John E. Connolly,et al. IL‐15‐induced human DC efficiently prime melanoma‐specific naive CD8+ T cells to differentiate into CTL , 2007, European journal of immunology.
[2] A. Eggermont,et al. A clinical development paradigm for cancer vaccines and related biologics. , 2007, Journal of immunotherapy.
[3] Michelle M. Sandau,et al. Accumulation of CD 8 T Cells Lymphopenia-Driven Proliferation and IL-15 Is Required for Sustained Jameson , 2007 .
[4] P. Conti,et al. IL-15 an immunoregulatory and anti-cancer cytokine. Recent advances. , 2006, Journal of experimental & clinical cancer research : CR.
[5] P. Burkett,et al. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. , 2006, Annual review of immunology.
[6] T. Fry,et al. Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8+ memory cell pool. , 2005, The Journal of clinical investigation.
[7] Y. Ravindranath,et al. Mechanisms of Superior Anti-Tumor Cytotoxic Response of Interleukin 15-Induced Lymphokine-Activated Killer Cells , 2005, Journal of immunotherapy.
[8] M. Caligiuri,et al. Failed Adoptive Immunotherapy with Tumor-Specific T Cells , 2004, Cancer Research.
[9] R. Miller,et al. IL-15 is superior to IL-2 in the generation of long-lived antigen specific memory CD4 and CD8 T cells in rhesus macaques. , 2004, Vaccine.
[10] A. Mackiewicz,et al. Effect of cyclophosphamide on tumorogenesis of the IL-6 and Hyper-IL-6 gene modified murine melanoma cells , 2004 .
[11] Rafał Kamiński,et al. Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice , 2004, Cancer Immunology, Immunotherapy.
[12] T. Yajima,et al. Interleukin-15 as an Immune Adjuvant To Increase the Efficacy of Mycobacterium bovis Bacillus Calmette-Guérin Vaccination , 2003, Infection and Immunity.
[13] T. Waldmann,et al. Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[14] C. Benoist,et al. Cytokine Requirements for Acute and Basal Homeostatic Proliferation of Naive and Memory CD8+ T Cells , 2002, The Journal of experimental medicine.
[15] M. Caligiuri,et al. Interleukin-2 and interleukin-15: immunotherapy for cancer. , 2002, Cytokine & growth factor reviews.
[16] F. Liew,et al. IL‐15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL‐12 / IL‐4 stimulation in vitro , 2002, European journal of immunology.
[17] J. Hsu,et al. Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain. , 2002, Journal of immunology.
[18] M. Caligiuri,et al. Interleukin 15: biology and relevance to human disease. , 2001, Blood.
[19] M. Wiznerowicz,et al. Antitumor effects of the combination therapy with TNF-α gene–modified tumor cells and interleukin 12 in a melanoma model in mice , 2000, Cancer Gene Therapy.
[20] T. Waldmann,et al. IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[21] P. Musiani,et al. Gene transfer of a secretable form of IL‐15 in murine adenocarcinoma cells: Effects on tumorigenicity, metastatic potential and immune response , 2000, International journal of cancer.
[22] J. D. Young,et al. The emerging role of IL-15 in NK-cell development. , 2000, Immunology today.
[23] T. Mak,et al. Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development. , 1997, Journal of immunology.
[24] M. Fenton,et al. IL-15 functions as a potent autocrine regulator of macrophage proinflammatory cytokine production: evidence for differential receptor subunit utilization associated with stimulation or inhibition. , 1997, Journal of immunology.
[25] A. Beaulieu,et al. Differential effects of interleukin-15 (IL-15) and IL-2 on human neutrophils: modulation of phagocytosis, cytoskeleton rearrangement, gene expression, and apoptosis by IL-15. , 1996, Blood.
[26] M. Caligiuri,et al. Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro. , 1995, The Journal of clinical investigation.
[27] M. Wick,et al. Studies evaluating the antitumor activity and toxicity of interleukin-15, a new T cell growth factor: comparison with interleukin-2. , 1995, Cellular immunology.
[28] F. Liew,et al. Interleukin-15 , 2020, Definitions.
[29] T. Waldmann,et al. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.