Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf

[1]  X. Estivill,et al.  Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis , 2001, Mechanisms of Development.

[2]  14th International Congress of Developmental Biology , 2001, Mechanisms of Development.

[3]  P. Traber,et al.  Cdx1 and cdx2 expression during intestinal development. , 2000, Gastroenterology.

[4]  H Clevers,et al.  Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine. , 2000, Development.

[5]  S. R. Hann,et al.  A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[6]  J. Gordon,et al.  Rac1 mutations produce aberrant epithelial differentiation in the developing and adult mouse small intestine. , 2000, Development.

[7]  D. Melton,et al.  Hedgehog signals regulate multiple aspects of gastrointestinal development. , 2000, Development.

[8]  P. Traber,et al.  The Caudal-related Homeodomain Protein Cdx1 Inhibits Proliferation of Intestinal Epithelial Cells by Down-regulation of D-type Cyclins* , 2000, The Journal of Biological Chemistry.

[9]  P. Overbeek,et al.  Tyrosinase-related protein 2 promoter targets transgene expression to ocular and neural crest-derived tissues. , 1999, Developmental biology.

[10]  J. Dagorn,et al.  Cdx1 promotes differentiation in a rat intestinal epithelial cell line. , 1999, Gastroenterology.

[11]  F. Campbell,et al.  A mouse model of intestinal stem cell function and regeneration. , 1999, Journal of cell science.

[12]  R. Playford,et al.  Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[13]  E. Morii,et al.  Different effect of various mutant MITF encoded by mi, Mior, or Miwh allele on phenotype of murine mast cells. , 1999, Blood.

[14]  C. Potten,et al.  Maintenance of functional stem cells in isolated and cultured adult intestinal epithelium. , 1999, Experimental cell research.

[15]  M. Seldin,et al.  Colonic hamartoma development by anomalous duplication in Cdx2 knockout mice. , 1999, Cancer research.

[16]  A. Quaroni,et al.  Involvement of p21(WAF1/Cip1) and p27(Kip1) in intestinal epithelial cell differentiation. , 1999, American journal of physiology. Cell physiology.

[17]  H. Arnold,et al.  Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. , 1999, Development.

[18]  A. Vescovi,et al.  Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo. , 1999, Science.

[19]  R. Shivdasani,et al.  A Possible Role for the High Mobility Group Box Transcription Factor Tcf-4 in Vertebrate Gut Epithelial Cell Differentiation* , 1999, The Journal of Biological Chemistry.

[20]  J. Bard,et al.  Table of mouse and rat developmental stages , 1999 .

[21]  P. Kaufmann.  The anatomical basis of mouse development , 1999 .

[22]  H Cheng,et al.  Clonal analysis of mouse intestinal epithelial progenitors. , 1999, Gastroenterology.

[23]  D. Champeval,et al.  Endothelin 3 selectively promotes survival and proliferation of neural crest-derived glial and melanocytic precursors in vitro. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[24]  G S Evans,et al.  The murine Cdx1 gene product localises to the proliferative compartment in the developing and regenerating intestinal epithelium. , 1998, Differentiation; research in biological diversity.

[25]  Hans Clevers,et al.  Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 , 1998, Nature Genetics.

[26]  M. Loeken,et al.  Identification of a New Binding Motif for the Paired Domain of Pax-3 and Unusual Characteristics of Spacing of Bipartite Recognition Elements on Binding and Transcription Activation* , 1998, The Journal of Biological Chemistry.

[27]  F. Giancotti,et al.  Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain , 1998 .

[28]  James M. Roberts,et al.  p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation , 1998, Current Biology.

[29]  K. Takeda,et al.  Epistatic relationship between Waardenburg Syndrome genes MITF and PAX3 , 1998, Nature Genetics.

[30]  M. Nguyen,et al.  Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently , 1998, Mechanisms of Development.

[31]  E. Price,et al.  MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes , 1998, Nature.

[32]  W. Pavan,et al.  Endothelin signalling in the development of neural crest-derived melanocytes , 1998 .

[33]  I. Jackson,et al.  Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo. , 1997, Developmental biology.

[34]  A. Copp,et al.  Role of the extracellular matrix in neural crest cell migration , 1997, Journal of anatomy.

[35]  A. Quaroni,et al.  Cell dynamics and differentiation of conditionally immortalized human intestinal epithelial cells. , 1997, Gastroenterology.

[36]  M. Peifer,et al.  Armadillo and dTCF: a marriage made in the nucleus. , 1997, Current opinion in genetics & development.

[37]  K. Kaestner,et al.  The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. , 1997, Genes & development.

[38]  W. Pavan,et al.  Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor. , 1997, Development.

[39]  A. McMahon,et al.  Analysis of neural crest cell migration in Splotch mice using a neural crest-specific LacZ reporter. , 1997, Developmental biology.

[40]  C. Der,et al.  The coupling of α6β4 integrin to Ras–MAP kinase pathways mediated by Shc controls keratinocyte proliferation , 1997 .

[41]  G. Cossu,et al.  Redefining the Genetic Hierarchies Controlling Skeletal Myogenesis: Pax-3 and Myf-5 Act Upstream of MyoD , 1997, Cell.

[42]  K. Chawengsaksophak,et al.  Homeosis and intestinal tumours in Cdx2 mutant mice , 1997, Nature.

[43]  L. Lim,et al.  Hepatocyte Nuclear Factor 3 / fork head Homolog 11 Is Expressed in Proliferating Epithelial and Mesenchymal Cells of Embryonic and Adult Tissues , 1996 .

[44]  K Takahashi,et al.  Functional Analysis of Microphthalmia-associated Transcription Factor in Pigment Cell-specific Transcription of the Human Tyrosinase Family Genes* , 1997, The Journal of Biological Chemistry.

[45]  K. Bille,et al.  Regulation of tyrosinase gene expression by cAMP in B16 melanoma cells involves two CATGTG motifs surrounding the TATA box: implication of the microphthalmia gene product , 1996, The Journal of cell biology.

[46]  James M. Roberts,et al.  Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein , 1996, The Journal of cell biology.

[47]  E. Morii,et al.  The recessive phenotype displayed by a dominant negative microphthalmia-associated transcription factor mutant is a result of impaired nucleation potential , 1996, Molecular and cellular biology.

[48]  T. Hunter,et al.  Dependence of Cyclin E-CDK2 Kinase Activity on Cell Anchorage , 1996, Science.

[49]  P. Gruss,et al.  Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes , 1995, Cell.

[50]  I. Jackson,et al.  Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles. , 1995, Genomics.

[51]  M. Ikawa,et al.  Green fluorescent protein as a marker in transgenic mice , 1995, Development, growth & differentiation.

[52]  S. Shibahara,et al.  Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene , 1995, Molecular and cellular biology.

[53]  F. Watt,et al.  Stem cell patterning and fate in human epidermis , 1995, Cell.

[54]  D. Scadden,et al.  Functional isolation and characterization of human hematopoietic stem cells. , 1995, Science.

[55]  E. Keenan,et al.  The Microphthalmia gene product interacts with the retinoblastoma protein in vitro and is a target for deregulation of melanocyte-specific transcription. , 1995, Oncogene.

[56]  S. Shibahara,et al.  Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene , 1994, Molecular and cellular biology.

[57]  C. Goding,et al.  Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator , 1994, Molecular and cellular biology.

[58]  James A. Vaught,et al.  microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family. , 1994, Genes & development.

[59]  S. Elledge,et al.  The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases , 1993, Cell.

[60]  J. Gerdes,et al.  The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins , 1993, The Journal of cell biology.

[61]  K. Vogan,et al.  The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene. , 1993, Genomics.

[62]  N. Jenkins,et al.  Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein , 1993, Cell.

[63]  A. Quaroni,et al.  Conditionally immortalized intestinal epithelial cells: novel approach for study of differentiated enterocytes. , 1993, The American journal of physiology.

[64]  M. Noble,et al.  Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[65]  K. Vogan,et al.  A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[66]  K. Steel,et al.  TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. , 1992, Development.

[67]  R. Greenspan,et al.  Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. , 1992, Development.

[68]  P. Gros,et al.  splotch (Sp2H ), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3 , 1991, Cell.

[69]  S. Nishikawa,et al.  Expression and function of c-kit in hemopoietic progenitor cells , 1991, The Journal of experimental medicine.

[70]  M. Goulding,et al.  Pax‐3, a novel murine DNA binding protein expressed during early neurogenesis. , 1991, The EMBO journal.

[71]  R. James,et al.  Homeobox gene expression in the intestinal epithelium of adult mice. , 1991, The Journal of biological chemistry.

[72]  M. Loeffler,et al.  Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. , 1990, Development.

[73]  T. Franz.  Defective ensheathment of motoric nerves in the Splotch mutant mouse. , 1990, Acta anatomica.

[74]  F. Watt,et al.  Stem cells: the generation and maintenance of cellular diversity. , 1989, Development.

[75]  P Gruss,et al.  A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. , 1988, Genes & development.

[76]  J. Gordon,et al.  Mechanisms underlying generation of gradients in gene expression within the intestine: an analysis using transgenic mice containing fatty acid binding protein-human growth hormone fusion genes. , 1988, Genes & development.

[77]  F. Meire,et al.  Waardenburg syndrome , 2020, Definitions.

[78]  R. Boissy,et al.  A mouse model for vitiligo. , 1986, The Journal of investigative dermatology.

[79]  L. Lajtha.  Stem cell concepts. , 1979, Nouvelle revue francaise d'hematologie.

[80]  W. Silvers.  The Coat Colors of Mice , 1979, Springer New York.

[81]  M. Mathan,et al.  Morphogenesis of fetal rat duodenal villi. , 1976, The American journal of anatomy.

[82]  H. Withers,et al.  Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation. , 1970, International journal of radiation biology and related studies in physics, chemistry, and medicine.

[83]  M. Dickie.  NEW SPLOTCH ALLELES IN THE MOUSE. , 1964, The Journal of heredity.

[84]  C. H. Waddington,et al.  Mechanisms of Development , 1955, Nature.

[85]  R. Auerbach.  Analysis of the developmental effects of a lethal mutation in the house mouse , 1954 .

[86]  F. Carnochan.  A NEW MUTATION IN THE HOUSE MOUSE , 1937 .