Sleep apnea syndrome. A critical review of the apnea index as a diagnostic criterion.

The utility of the apnea index (number of apneic events per hour of sleep) in diagnosing sleep apnea syndrome is reviewed. Data from currently extant reports indicate that many otherwise normal, aging subjects may be classified as having sleep apnea syndrome based on the current diagnostic threshold of five apneic episodes per hour: A chi 2 analysis suggests a relationship between age and level of sleep apnea. Several other reports indicate that use of a threshold of five apneic episodes per hour does not reliably predict increased health risk or somnolence in aging subjects. Adjustment of the apnea index, based on studies of aging normal subjects and of aging patients with sleep apnea syndrome is necessary to ensure reliable results in clinical and research applications.

[1]  D Kurtz,et al.  Breathing during sleep in normal young and elderly subjects: hypopneas, apneas, and correlated factors. , 1983, Sleep.

[2]  M. Vitiello,et al.  Sleep apnea: relationship to age, sex, and Alzheimer's dementia. , 1983, Sleep.

[3]  M. Littner,et al.  Sleep related breathing disorders in older men: A search for underlying mechanisms , 1982, Neurobiology of Aging.

[4]  E. Bixler,et al.  Sleep apneic activity in a normal population. , 1982, Research communications in chemical pathology and pharmacology.

[5]  P. Mangin,et al.  Respiration during sleep in the aged human. , 1982, Journal of gerontology.

[6]  D F Kripke,et al.  Sleep apnea and nocturnal myoclonus in a senior population. , 1981, Sleep.

[7]  E. Poole.  Diagnostic classification of sleep and arousal disorders—sleep Vol. 2, no. 1. 137 pp. Raven Press, New York (1979) $15.00 , 1981, Neuroscience.

[8]  A. J. Block,et al.  Sleep-disordered breathing and nocturnal oxygen desaturation in postmenopausal women. , 1980, The American journal of medicine.

[9]  A. J. Block,et al.  Sleep Apnea, Hypopnea and Oxygen Desaturation in Normal Subjects: A Strong Male Predominance , 1980 .

[10]  J. Krieger,et al.  Les modifications respiratoires au cours du sommeil du sujet agé normal , 1980 .

[11]  M. Carskadon,et al.  Sleep and daytime sleepiness in the elderly. , 1980, Journal of geriatric psychiatry.

[12]  R. Greenberg.  Insomnia and sleep disturbances in the aged. , 1980, Journal of geriatric psychiatry.

[13]  P. Howard.  Sleep Disorders Classification Committee, Association of Sleep Disorders Centers , 1979 .

[14]  Christian Guilleminault,et al.  Clinical overview of the sleep apnea syndromes , 1978 .

[15]  P Webb,et al.  Periodic breathing during sleep. , 1974, Journal of applied physiology.

[16]  P. Meehl.  Psychodiagnosis: Selected Papers , 1973 .