Visceral adipose tissue impairs insulin secretion and insulin sensitivity but not energy expenditure in obesity.

[1]  G. Holm,et al.  Potential importance of the muscles for the development of insulin resistance in obesity. , 2009, Acta medica Scandinavica. Supplementum.

[2]  J. Hill,et al.  Measuring the thermic effect of food. , 1996, The American journal of clinical nutrition.

[3]  T. Horton,et al.  Post-prandial thermogenesis with ephedrine, caffeine and aspirin in lean, pre-disposed obese and obese women. , 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[4]  E. Ravussin,et al.  Thermic effect of food in humans: methods and results from use of a respiratory chamber. , 1995, The American journal of clinical nutrition.

[5]  L. V. Van Gaal,et al.  Sex hormones, body fat distribution, resting metabolic rate and glucose-induced thermogenesis in premenopausal obese women. , 1994, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[6]  B. Richelsen,et al.  Abdominal obesity is associated with insulin resistance and reduced glycogen synthetase activity in skeletal muscle. , 1993, Metabolism: clinical and experimental.

[7]  M. G. Carlson,et al.  Impact of Obesity on Insulin Action in NIDDM , 1993, Diabetes.

[8]  P. Deurenberg,et al.  Waist-hip ratio is a poor predictor of changes in visceral fat. , 1993, The American journal of clinical nutrition.

[9]  A. Golay.  Blunted glucose-induced thermogenesis: a factor contributing to relapse of obesity. , 1993, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[10]  G Pacini,et al.  Beta-cell hypersecretion and not reduced hepatic insulin extraction is the main cause of hyperinsulinemia in obese nondiabetic subjects. , 1992, Metabolism: clinical and experimental.

[11]  M. Zamboni,et al.  Resting metabolic rate, body-fat distribution, and visceral fat in obese women. , 1992, The American journal of clinical nutrition.

[12]  P. Deurenberg,et al.  Visceral fat accumulation in obese subjects: relation to energy expenditure and response to weight loss. , 1992, The American journal of physiology.

[13]  J. Lancaster,et al.  Total Body Fat Content and Fat Topography Are Associated Differently With In Vivo Glucose Metabolism in Nonobese and Obese Nondiabetic Women , 1992, Diabetes.

[14]  I. Godsland,et al.  Effect of body mass index and fat distribution on insulin sensitivity, secretion, and clearance in nonobese healthy men. , 1992, The Journal of clinical endocrinology and metabolism.

[15]  P. Björntorp.  Metabolic Implications of Body Fat Distribution , 1991, Diabetes Care.

[16]  A. Golay,et al.  Evolution of glucose induced thermogenesis in obese subjects with and without diabetes: a six-year follow-up study. , 1991, International journal of obesity.

[17]  H. K. Lee,et al.  Intra-abdominal fat is associated with decreased insulin sensitivity in healthy young men. , 1991, Metabolism: clinical and experimental.

[18]  L. Groop,et al.  Obesity and insulin resistance in humans: a dose-response study. , 1990, Metabolism: clinical and experimental.

[19]  J. Gerich,et al.  Impact of obesity on insulin action in volunteers with normal glucose tolerance: demonstration of a threshold for the adverse effect of obesity. , 1990, The Journal of clinical endocrinology and metabolism.

[20]  Y. Schutz,et al.  Energy expenditure in obesity and diabetes. , 1988, Diabetes/metabolism reviews.

[21]  H. Makino,et al.  First-phase insulin response to glucose in nonobese or obese subjects with glucose intolerance: analysis by C-peptide secretion rate. , 1988, Metabolism: clinical and experimental.

[22]  W. Chumlea,et al.  Specific resistivity used to estimate fat-free mass from segmental body measures of bioelectric impedance. , 1988, The American journal of clinical nutrition.

[23]  M. Polansky,et al.  Thermic effect of food in lean and obese men. , 1988, The Journal of clinical investigation.

[24]  O. Owen.  Resting metabolic requirements of men and women. , 1988, Mayo Clinic proceedings.

[25]  P. Deurenberg,et al.  Resting metabolic rate and diet-induced thermogenesis in abdominal and gluteal-femoral obese women before and after weight reduction. , 1988, The American journal of clinical nutrition.

[26]  C Bogardus,et al.  Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. , 1987, The Journal of clinical investigation.

[27]  E. A. Sims,et al.  Effect of diet on energy expenditure and plasma norepinephrine in lean and obese Pima Indians. , 1986, Metabolism: clinical and experimental.

[28]  H C Lukaski,et al.  Validation of tetrapolar bioelectrical impedance method to assess human body composition. , 1986, Journal of applied physiology.

[29]  L. Christin,et al.  Enteral versus parenteral nutrition: comparison of energy metabolism in lean and moderately obese women. , 1986, The American journal of clinical nutrition.

[30]  B. Gutin,et al.  Thermic effect of food at rest, during exercise, and after exercise in lean and obese men of similar body weight. , 1985, The Journal of clinical investigation.

[31]  H C Lukaski,et al.  Assessment of fat-free mass using bioelectrical impedance measurements of the human body. , 1985, The American journal of clinical nutrition.

[32]  S. Lillioja,et al.  Relationship between degree of obesity and in vivo insulin action in man. , 1985, The American journal of physiology.

[33]  Y. Schutz,et al.  Diet-induced thermogenesis measured over a whole day in obese and nonobese women. , 1984, The American journal of clinical nutrition.

[34]  E. H. Twizell.  The mathematical modeling of metabolic and endocrine systems: E.R. Carson, C. Cobelli and L. Finkelstein John Wiley and Sons, Chichester, Sussex, UK, 394 pp., £45.15, 1983 , 1984 .

[35]  H. Yki-Järvinen,et al.  Effects of Body Composition on Insulin Sensitivity , 1983, Diabetes.

[36]  B. Gutin,et al.  Thermic effects of food and exercise in lean and obese women. , 1983, Metabolism: clinical and experimental.

[37]  G. Borkan,et al.  Assessment of abdominal fat content by computed tomography. , 1982, The American journal of clinical nutrition.

[38]  P. Savage,et al.  A Simplified Method Using Somatostatin to Assess In Vivo Insulin Resistance over a Range of Obesity , 1979, Diabetes.

[39]  Y. Z. Ider,et al.  Quantitative estimation of insulin sensitivity. , 1979, The American journal of physiology.

[40]  E. Newsholme,et al.  The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. , 1963, Lancet.

[41]  A. Astrup,et al.  24-hour energy expenditure and substrate oxidation rates are unaffected by body fat distribution in obese women. , 1994, Metabolism: clinical and experimental.

[42]  J. Wahren,et al.  Heat leakage across the abdominal wall and meal-induced thermogenesis in normal-weight and obese subjects. , 1992, Metabolism: clinical and experimental.

[43]  P. Deurenberg,et al.  Resting energy expenditure in women: impact of obesity and body-fat distribution. , 1990, Metabolism: clinical and experimental.

[44]  L. V. Van Gaal,et al.  Decreased diet-induced thermogenesis in gluteal-femoral obesity. , 1989, Journal of the American College of Nutrition.