FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgfβ1 signaling pathway
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A. D. de Kloet | E. Krause | Z. Tao | Zhiyong Cheng | Jinying Yang | Karen Scott | Louise D. Zheng | Xinran Hu | James F Collins | Limin Shi
[1] Z. Tao,et al. Hormonal regulation of metabolism—recent lessons learned from insulin and estrogen , 2023, Clinical science.
[2] Dongxue Wei,et al. Capsaicin induces ferroptosis of NSCLC by regulating SLC7A11/GPX4 signaling in vitro , 2022, Scientific Reports.
[3] M. Hacker,et al. Brown Adipose Tissue Prevalence Is Lower in Obesity but Its Metabolic Activity Is Intact , 2022, Frontiers in Endocrinology.
[4] Zhiyong Cheng. FoxO transcription factors in mitochondrial homeostasis , 2022, The Biochemical journal.
[5] P. Seale,et al. Adipose-tissue plasticity in health and disease , 2022, Cell.
[6] K. Tsuchiya,et al. FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting , 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] E. Seki,et al. Hepatocyte TGF‐β Signaling Inhibiting WAT Browning to Promote NAFLD and Obesity Is Associated With Let‐7b‐5p , 2022, Hepatology communications.
[8] M. Samaan,et al. Iron deficiency anaemia: pathophysiology, assessment, practical management , 2022, BMJ open gastroenterology.
[9] C. Forsyth,et al. Non-anaemic iron deficiency , 2021, Australian prescriber.
[10] Soonkyu Chung,et al. Dietary Iron Deficiency Modulates Adipocyte Iron Homeostasis, Adaptive Thermogenesis, and Obesity in C57BL/6 Mice. , 2021, The Journal of nutrition.
[11] M. White,et al. FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance , 2021, Cell reports.
[12] W. Gu,et al. Sirt1 coordinates with ERα to regulate autophagy and adiposity , 2021, Cell Death Discovery.
[13] Wei Guo,et al. Constitutive GLI1 expression in chondrosarcoma is regulated by major vault protein via mTOR/S6K1 signaling cascade , 2021, Cell Death & Differentiation.
[14] A. Patapoutian,et al. A role of PIEZO1 in iron metabolism in mice and humans , 2021, Cell.
[15] D. I. Brierley,et al. Central and peripheral GLP-1 systems independently suppress eating , 2021, Nature Metabolism.
[16] R. O’Keefe,et al. FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis , 2020, Proceedings of the National Academy of Sciences.
[17] Hongyan Shi,et al. Compromised browning plasticity of primary subcutaneous adipocytes derived from overweight Chinese adults , 2020, Diabetology & Metabolic Syndrome.
[18] M. Puzianowska-Kuźnicka,et al. Induction of Adipose Tissue Browning as a Strategy to Combat Obesity , 2020, International journal of molecular sciences.
[19] D. Accili,et al. The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase–leukotriene B4 axis , 2020, Proceedings of the National Academy of Sciences.
[20] H. Itoh,et al. FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression , 2019, iScience.
[21] T. Duffy,et al. FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling , 2019, The Journal of Biological Chemistry.
[22] S. Farmer,et al. CIDEA Transcriptionally Regulates UCP1 for Britening and Thermogenesis in Human Fat Cells , 2019, iScience.
[23] Zhiyong Cheng. The FoxO–Autophagy Axis in Health and Disease , 2019, Trends in Endocrinology & Metabolism.
[24] K. Lyons,et al. The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage , 2019, Proceedings of the National Academy of Sciences.
[25] Shaodong Guo,et al. Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1. , 2019, The Journal of endocrinology.
[26] C. Shively,et al. Skeletal Muscle Mitochondrial Respiration Is Elevated in Female Cynomolgus Macaques Fed a Western Compared with a Mediterranean Diet. , 2019, The Journal of nutrition.
[27] S. Cloonan,et al. Mitochondrial Iron in Human Health and Disease. , 2019, Annual review of physiology.
[28] Edward T Chouchani,et al. Metabolic adaptation and maladaptation in adipose tissue , 2019, Nature Metabolism.
[29] P. Scherer,et al. Adipogenesis and metabolic health , 2019, Nature Reviews Molecular Cell Biology.
[30] C. Camaschella. Iron deficiency. , 2019, Blood.
[31] M. Harmsen,et al. Fibroblast growth factor-2, but not the adipose tissue-derived stromal cells secretome, inhibits TGF-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts , 2018, Scientific Reports.
[32] J. P. McCoy,et al. TGF-β receptor 1 regulates progenitors that promote browning of white fat , 2018, Molecular metabolism.
[33] Dongmin Liu,et al. Estradiol signaling mediates gender difference in visceral adiposity via autophagy , 2018, Cell Death & Disease.
[34] N. Mitro,et al. HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning , 2017, Nature Communications.
[35] S. Rivella,et al. Targeting iron metabolism in drug discovery and delivery , 2017, Nature Reviews Drug Discovery.
[36] S. Rivella,et al. A Red Carpet for Iron Metabolism , 2017, Cell.
[37] S. Rane,et al. TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis* , 2017, The Journal of Biological Chemistry.
[38] Y. C. Long,et al. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes , 2016, Cell Death Discovery.
[39] Y. C. Long,et al. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes , 2016, Cell cycle.
[40] J. Yamauchi,et al. FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice. , 2016, Endocrinology.
[41] Zhiyong Cheng. FoxO1: mute for a tuned metabolism? , 2015, Trends in Endocrinology & Metabolism.
[42] R. DePinho,et al. FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization , 2015, Nature Communications.
[43] Bhaskar Ponugoti,et al. FOXO1 differentially regulates both normal and diabetic wound healing , 2015, The Journal of cell biology.
[44] M. Klingenspor,et al. Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. , 2015, Endocrinology.
[45] L. Sidossis,et al. Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis. , 2015, The Journal of clinical investigation.
[46] R. MacPherson,et al. The contribution of IL-6 to beta 3 adrenergic receptor mediated adipose tissue remodeling , 2015, Physiological reports.
[47] T. Schulz,et al. Disruption of insulin signaling in Myf5-expressing progenitors leads to marked paucity of brown fat but normal muscle development. , 2015, Endocrinology.
[48] P. Zou,et al. Tamoxifen reduces fat mass by boosting reactive oxygen species , 2015, Cell Death and Disease.
[49] P. Zou,et al. Targeting FoxO1 with AS1842856 Suppresses Adipogenesis , 2014, Cell cycle.
[50] E. Rosen,et al. Characterization of Cre recombinase models for the study of adipose tissue , 2014, Adipocyte.
[51] D. Guertin,et al. Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed , 2014, Nature Communications.
[52] L. Sidossis,et al. Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress (1160.5) , 2014, Cell metabolism.
[53] P. Scherer,et al. Improved methodologies for the study of adipose biology: insights gained and opportunities ahead , 2014, Journal of Lipid Research.
[54] A. Roscher,et al. Digital image analysis approach for lipid droplet size quantitation of Oil Red O-stained cultured cells. , 2014, Analytical biochemistry.
[55] B. Kingwell,et al. Ephedrine activates brown adipose tissue in lean but not obese humans , 2013, Diabetologia.
[56] A. Rissanen,et al. Blunted metabolic responses to cold and insulin stimulation in brown adipose tissue of obese humans , 2013, Obesity.
[57] Bhaskar Ponugoti,et al. FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress , 2013, The Journal of cell biology.
[58] C. Kahn,et al. Lessons on Conditional Gene Targeting in Mouse Adipose Tissue , 2013, Diabetes.
[59] Wei Jia,et al. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis , 2013, Proceedings of the National Academy of Sciences.
[60] A. Hata,et al. Targeting the TGFβ signalling pathway in disease , 2012, Nature Reviews Drug Discovery.
[61] A. Efeyan,et al. Pten positively regulates brown adipose function, energy expenditure, and longevity. , 2012, Cell metabolism.
[62] M. White,et al. The AKTion in non-canonical insulin signaling , 2012, Nature Medicine.
[63] T. Kitamura,et al. FoxO1 as a double-edged sword in the pancreas: analysis of pancreas- and β-cell-specific FoxO1 knockout mice. , 2012, American journal of physiology. Endocrinology and metabolism.
[64] C. Kahn,et al. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1 , 2012, Nature Medicine.
[65] P. Sun,et al. Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling. , 2011, Cell metabolism.
[66] M. Brand,et al. Assessing mitochondrial dysfunction in cells , 2011, The Biochemical journal.
[67] Zhiyong Cheng,et al. Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. , 2011, Antioxidants & redox signaling.
[68] S. Offermanns,et al. Tamoxifen‐inducible Cre‐mediated recombination in adipocytes , 2010, Genesis.
[69] M. White,et al. Insulin signaling meets mitochondria in metabolism , 2010, Trends in Endocrinology & Metabolism.
[70] P. Puigserver,et al. Foxo1 integrates insulin signaling with mitochondrial function in the liver , 2009, Nature Medicine.
[71] S. Cinti. Transdifferentiation properties of adipocytes in the adipose organ. , 2009, American journal of physiology. Endocrinology and metabolism.
[72] Sunmin Park,et al. The Irs1 Branch of the Insulin Signaling Cascade Plays a Dominant Role in Hepatic Nutrient Homeostasis , 2009, Molecular and Cellular Biology.
[73] K. Mather. Surrogate measures of insulin resistance: of rats, mice, and men. , 2009, American journal of physiology. Endocrinology and metabolism.
[74] R. DePinho,et al. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. , 2008, Cell metabolism.
[75] H. Kiyonari,et al. Forkhead Transcription Factor FoxO1 in Adipose Tissue Regulates Energy Storage and Expenditure , 2008, Diabetes.
[76] Yonghong Xiao,et al. FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis , 2007, Cell.
[77] Hiroyuki Aburatani,et al. Skeletal Muscle FOXO1 (FKHR) Transgenic Mice Have Less Skeletal Muscle Mass, Down-regulated Type I (Slow Twitch/Red Muscle) Fiber Genes, and Impaired Glycemic Control*[boxs] , 2004, Journal of Biological Chemistry.
[78] A. Gils,et al. Plasminogen activator inhibitor-1. , 2004, Current medicinal chemistry.
[79] H. Rousset,et al. Polycythaemia and iron deficiency , 2003, The Lancet.
[80] P. Chambon,et al. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[81] P. Morange,et al. Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity. , 2000, Diabetes.
[82] H. Wajcman,et al. Abnormal hemoglobins with high oxygen affinity and erythrocytosis. , 1996, Hematology and cell therapy.
[83] Z. Tao,et al. Assessing the Activity of Transcription Factor FoxO1. , 2023, Methods in molecular biology.
[84] Z. Tao,et al. Autophagy in Adipocyte Differentiation. , 2019, Methods in molecular biology.
[85] J. Heeren,et al. Adipose tissue browning and metabolic health , 2014, Nature Reviews Endocrinology.
[86] D. Accili,et al. The forkhead transcription factor Foxo1 regulates adipocyte differentiation. , 2003, Developmental cell.
[87] J. Thiery,et al. Fibroblast growth factor-2. , 2000, The international journal of biochemistry & cell biology.