Histone deacetylase inhibitors impair the host immune response against Mycobacterium tuberculosis infection.

[1]  Hong-Xia Wang,et al.  CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy , 2018, Theranostics.

[2]  J. Wan,et al.  Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice. , 2018, Carbohydrate polymers.

[3]  W. Sha,et al.  MicroRNA-27a controls the intracellular survival of Mycobacterium tuberculosis by regulating calcium-associated autophagy , 2018, Nature Communications.

[4]  C. Tsatsanis,et al.  Histone methylation and acetylation in macrophages as a mechanism for regulation of inflammatory responses , 2018, Journal of cellular physiology.

[5]  Xiaowei Tang,et al.  Histone deacetylase 6 inhibitor enhances resistance to Mycobacterium tuberculosis infection through innate and adaptive immunity in mice. , 2018, Pathogens and disease.

[6]  Yu-Jin Jung,et al.  Lysophosphatidylcholine Promotes Phagosome Maturation and Regulates Inflammatory Mediator Production Through the Protein Kinase A–Phosphatidylinositol 3 Kinase–p38 Mitogen-Activated Protein Kinase Signaling Pathway During Mycobacterium tuberculosis Infection in Mouse Macrophages , 2018, Front. Immunol..

[7]  H. Shen,et al.  IL-12+IL-18 Cosignaling in Human Macrophages and Lung Epithelial Cells Activates Cathelicidin and Autophagy, Inhibiting Intracellular Mycobacterial Growth , 2018, The Journal of Immunology.

[8]  Alimuddin Zumla,et al.  Evaluation of the efficacy of valproic acid and suberoylanilide hydroxamic acid (vorinostat) in enhancing the effects of first-line tuberculosis drugs against intracellular Mycobacterium tuberculosis. , 2018, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[9]  W. Jeong,et al.  Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex , 2017, Nature Communications.

[10]  F. Sánchez‐Madrid,et al.  HDAC6 controls innate immune and autophagy responses to TLR-mediated signalling by the intracellular bacteria Listeria monocytogenes , 2017, PLoS pathogens.

[11]  S. Santos,et al.  Nuclear sirtuins and inflammatory signaling pathways. , 2017, Cytokine & growth factor reviews.

[12]  J. Potempa,et al.  Epigenetic regulation in bacterial infections: targeting histone deacetylases , 2017, Critical reviews in microbiology.

[13]  M. Stiborová,et al.  Histone Deacetylase Inhibitors as Anticancer Drugs , 2017, International journal of molecular sciences.

[14]  Nakul M. Shah,et al.  DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats , 2017, Nature Genetics.

[15]  C. Bloomfield,et al.  Randomized Phase II Study of Azacitidine Alone or in Combination With Lenalidomide or With Vorinostat in Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: North American Intergroup Study SWOG S1117. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  E. Newell,et al.  Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis , 2017, Science Immunology.

[17]  Virapong Prachayasittikul,et al.  Exploring the epigenetic drug discovery landscape , 2017, Expert opinion on drug discovery.

[18]  Yung-Yang Liu,et al.  Trichostatin A attenuates ventilation-augmented epithelial-mesenchymal transition in mice with bleomycin-induced acute lung injury by suppressing the Akt pathway , 2017, PloS one.

[19]  D. Tang,et al.  Ferroptosis: process and function , 2016, Cell Death and Differentiation.

[20]  R. Kay,et al.  Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion , 2014, EMBO molecular medicine.

[21]  Xiaowei Wang,et al.  miRDB: an online resource for microRNA target prediction and functional annotations , 2014, Nucleic Acids Res..

[22]  M. Rosengart,et al.  CaMKIV-Dependent Preservation of mTOR Expression Is Required for Autophagy during Lipopolysaccharide-Induced Inflammation and Acute Kidney Injury , 2014, The Journal of Immunology.

[23]  T. Curiel,et al.  Combined autophagy and HDAC inhibition , 2014, Autophagy.

[24]  Young Kil Park,et al.  Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. , 2012, Cell host & microbe.

[25]  T. Calandra,et al.  Histone deacetylase inhibitors impair antibacterial defenses of macrophages. , 2011, The Journal of infectious diseases.

[26]  M. Sweet,et al.  Histone deacetylases as regulators of inflammation and immunity. , 2011, Trends in immunology.

[27]  P. François,et al.  Histone deacetylase inhibitors impair innate immune responses to Toll-like receptor agonists and to infection. , 2011, Blood.

[28]  K. Anderson,et al.  HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Myeloid Dendritic Cells , 2010, Leukemia.

[29]  D. Shin,et al.  Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. , 2009, Cell host & microbe.

[30]  A. Goldhirsch,et al.  A phase I–II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma , 2009, British Journal of Cancer.

[31]  K. Schroder,et al.  Histone deacetylase inhibitors decrease Toll‐like receptor‐mediated activation of proinflammatory gene expression by impairing transcription factor recruitment , 2007, Immunology.

[32]  Mark J. Smyth,et al.  Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma , 2007, Proceedings of the National Academy of Sciences.

[33]  K. Fischbeck,et al.  Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy. , 2007, The Journal of clinical investigation.

[34]  C. Pérez-Plasencia,et al.  A phase II study of epigenetic therapy with hydralazine and magnesium valproate to overcome chemotherapy resistance in refractory solid tumors , 2007, BMC Cancer.

[35]  R. Rizzuto,et al.  Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. , 2007, Molecular cell.

[36]  E. Sausville,et al.  Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[37]  L. Schwartz,et al.  Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[38]  Joseph Keane,et al.  Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent , 2001 .

[39]  J. V. Falvo,et al.  Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation. , 2013, Advances in immunology.