Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers.

STUDY OBJECTIVES Although there are considerable data demonstrating the impact of shift work on sleep and alertness, little research has examined the prevalence and consequences of shift work sleep disorder in comparison to the difficulties with insomnia and excessive sleepiness experienced by day workers. The present study was designed to determine the relative prevalence and negative consequences associated with shift work sleep disorder in a representative sample drawn from the working population of metropolitan Detroit. DESIGN Random-digit dialing techniques were used to assess individuals regarding their current work schedules and a variety of sleep- and non-sleep-related outcomes. SETTING Detroit tricounty population. PARTICIPANTS A total of 2,570 individuals aged 18 to 65 years from a representative community-based sample including 360 people working rotating shifts, 174 people working nights, and 2036 working days. MEASUREMENTS AND RESULTS Using standardized techniques, individuals were assessed for the presence of insomnia and excessive sleepiness, based on DSM-IV and ICSD criteria. Those individuals with either insomnia or excessive sleepiness and who were currently working rotating or night schedules were classified as having shift work sleep disorder. Occupational, behavioral, and health-related outcomes were also measured. Individuals who met criteria for shift work sleep disorder had significantly higher rates of ulcers (odds ratio = 4.18, 95% confidence interval = 2.00-8.72), sleepiness-related accidents, absenteeism, depression, and missed family and social activities more frequently compared to those shift workers who did not meet criteria (P < .05). Importantly, in most cases, the morbidity associated with shift work sleep disorder was significantly greater than that experienced by day workers with identical symptoms. CONCLUSION These findings suggest that individuals with shift work sleep disorder are at risk for significant behavioral and health-related morbidity associated with their sleep-wake symptomatology. Further, it suggests that the prevalence of shift work sleep disorder is approximately 10% of the night and rotating shift work population.

[1]  H. Goto,et al.  Peptic ulcer is prevalent among shift workers , 1987, Digestive Diseases and Sciences.

[2]  L. Melton,et al.  Obesity is Associated with Increased Risk of Gastrointestinal Symptoms: A Population-Based Study , 2004, American Journal of Gastroenterology.

[3]  P. Doyle,et al.  The National Women's Health Study: assembly and description of a population-based reproductive cohort , 2004, BMC public health.

[4]  Anne Johanne Søgaard,et al.  Health Study : The impact of self-selection in a large , population-based survey , 2015 .

[5]  D. Dinges,et al.  Systematic interindividual differences in neurobehavioral impairment from sleep loss: evidence of trait-like differential vulnerability. , 2004, Sleep.

[6]  Christopher Drake,et al.  Vulnerability to stress-related sleep disturbance and hyperarousal. , 2004, Sleep.

[7]  R. Bootzin,et al.  Sleep and reported daytime sleepiness in normal subjects: the Sleep Heart Health Study. , 2004, Sleep.

[8]  Nader Rifai,et al.  Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. , 2004, Journal of the American College of Cardiology.

[9]  Torbjörn Åkerstedt,et al.  Tolerance to shift work—how does it relate to sleep and wakefulness? , 2004, International archives of occupational and environmental health.

[10]  C. Eastman,et al.  Combinations of Bright Light, Scheduled Dark, Sunglasses, and Melatonin to Facilitate Circadian Entrainment to Night Shift Work , 2003, Journal of biological rhythms.

[11]  T. Åkerstedt,et al.  Hormonal changes in satisfied and dissatisfied shift workers across a shift cycle. , 2003, Journal of applied physiology.

[12]  T. Young,et al.  Predictors of objective sleep tendency in the general population. , 2003, Sleep.

[13]  Christian Cajochen,et al.  A Phase Response Curve to Single Bright Light Pulses in Human Subjects , 2003, The Journal of physiology.

[14]  D. Dinges,et al.  The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation. , 2003, Sleep.

[15]  A. Knutsson,et al.  Health disorders of shift workers. , 2003, Occupational medicine.

[16]  E. F. Colecchia,et al.  Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

[17]  T. Åkerstedt Shift work and disturbed sleep/wakefulness. , 1998, Occupational medicine.

[18]  Lino Nobili,et al.  Sleepiness and sleep disorders in shift workers: a study on a group of italian police officers. , 2002, Sleep.

[19]  T. Åkerstedt,et al.  Work load and work hours in relation to disturbed sleep and fatigue in a large representative sample. , 2002, Journal of psychosomatic research.

[20]  Patrick Lemoine,et al.  Prevalence and consequences of sleep disorders in a shift worker population. , 2002, Journal of psychosomatic research.

[21]  K. Müller,et al.  The effect of an irregular shift system on sleepiness at work in train drivers and railway traffic controllers , 2002, Journal of sleep research.

[22]  N. Lamond,et al.  Daytime cardiac autonomic activity during one week of continuous night shift. , 2001, Journal of human ergology.

[23]  C. Drake,et al.  Effects of rapid versus slow accumulation of eight hours of sleep loss. , 2001, Psychophysiology.

[24]  Thomas M. Beers Flexible Schedules and Shift Work. , 2000 .

[25]  J J Pilcher,et al.  Work/rest cycles in railroad operations: effects of shorter than 24-h shift work schedules and on-call schedules on sleep , 2000, Ergonomics.

[26]  Allen I. Huffcutt,et al.  Differential effects of permanent and rotating shifts on self-report sleep length: a meta-analytic review. , 2000, Sleep.

[27]  M. Johns,et al.  Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth sleepiness scale: Failure of the MSLT as a gold standard , 2000, Journal of sleep research.

[28]  C. Simon,et al.  Twenty-four-hour rhythms of plasma glucose and insulin secretion rate in regular night workers. , 2000, American journal of physiology. Endocrinology and metabolism.

[29]  P. Zee,et al.  Chronic circadian desynchronization decreases the survival of animals with cardiomyopathic heart disease. , 1998, American journal of physiology. Heart and circulatory physiology.

[30]  M. Härmä,et al.  Joint effect of shift work and adverse life-style factors on the risk of coronary heart disease. , 1998, Scandinavian journal of work, environment & health.

[31]  C. Guilleminault,et al.  Rapid shift in peak melatonin secretion associated with improved performance in short shift work schedule. , 1997, Sleep.

[32]  J. Anthony,et al.  Natural history of Diagnostic Interview Schedule/DSM-IV major depression. The Baltimore Epidemiologic Catchment Area follow-up. , 1997, Archives of general psychiatry.

[33]  M. Härmä,et al.  Shift work, occupation and coronary heart disease over 6 years of follow-up in the Helsinki Heart Study. , 1997, Scandinavian journal of work, environment & health.

[34]  A. Pack,et al.  Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per night. , 1997, Sleep.

[35]  R. Chervin,et al.  Comparison of the results of the Epworth Sleepiness Scale and the Multiple Sleep Latency Test. , 1997, Journal of psychosomatic research.

[36]  Claude Gronfier,et al.  Growth hormone secretion in night workers. , 1997, Chronobiology international.

[37]  A. Reinberg,et al.  Interindividual differences in the flexibility of human temporal organization: pertinence to jet lag and shiftwork. , 1997, Chronobiology international.

[38]  G. Libro,et al.  Quality of life in shift work syndrome. , 1996, Functional neurology.

[39]  N. Cherry,et al.  Shiftwork and mortality from ischaemic heart disease. , 1996, Occupational and environmental medicine.

[40]  G. Brandenberger,et al.  Internal dissociation of the circadian markers of the cortisol rhythm in night workers. , 1996, The American journal of physiology.

[41]  Richard E. Kronauer,et al.  Dose-response relationships for resetting of human circadian clock by light , 1996, Nature.

[42]  G. Richardson,et al.  Circadian rhythm sleep disorders: pathophysiology and treatment. , 1996, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[43]  D. Dijk,et al.  Use of bright light to treat maladaptation to night shift work and circadian rhythm sleep disorders , 1995, Journal of sleep research.

[44]  J. Manson,et al.  Prospective study of shift work and risk of coronary heart disease in women. , 1995, Circulation.

[45]  C. Eastman,et al.  Circadian rhythm adaptation to simulated night shift work: effect of nocturnal bright-light duration. , 1995, Sleep.

[46]  G. Brandenberger,et al.  The circadian thyrotropin rhythm is delayed in regular night workers , 1995, Neuroscience Letters.

[47]  C A Czeisler,et al.  The effect of light on the human circadian pacemaker. , 1995, Ciba Foundation symposium.

[48]  C A Czeisler,et al.  Sleep and alertness in a 12-hour rotating shift work environment. , 1994, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[49]  Harrington Jm,et al.  Shift work and health--a critical review of the literature on working hours , 1994 .

[50]  C. Eastman,et al.  Dark goggles and bright light improve circadian rhythm adaptation to night-shift work. , 1994, Sleep.

[51]  A. Lewy,et al.  Melatonin rhythms in night shift workers. , 1992, Sleep.

[52]  M. Johns,et al.  Reliability and factor analysis of the Epworth Sleepiness Scale. , 1992, Sleep.

[53]  P Knauth,et al.  The relation of shift work tolerance to the circadian adjustment. , 1992, Chronobiology international.

[54]  Anna Wirz-Justice,et al.  A human phase-response curve to light , 1991, Neuroscience Letters.

[55]  T. Monk,et al.  Is the poor sleep of shift workers a disorder? , 1991, The American journal of psychiatry.

[56]  D Dawson,et al.  Timed exposure to bright light improves sleep and alertness during simulated night shifts. , 1991, Sleep.

[57]  J K Walsh,et al.  Sleepiness/alertness on a simulated night shift following sleep at home with triazolam. , 1991, Sleep.

[58]  P. O’Brien,et al.  Exposure to bright light and darkness to treat physiologic maladaptation to night work , 1991 .

[59]  C A Czeisler,et al.  Impaired driving performance in shiftworkers: the role of the circadian system in a multifactorial model. , 1990, Alcohol, drugs, and driving : abstracts and reviews.

[60]  H. Cohen,et al.  Major Depression and the NIMH Diagnostic Interview Schedule: Validation in Medically Ill Hospitalized Patients , 1990, International Journal of Psychiatry in Medicine.

[61]  S Folkard Shift work--a growing occupational hazard. , 1989, Occupational health; a journal for occupational health nurses.

[62]  A. Knutsson,et al.  Shift work and coronary heart disease. , 1989, Scandinavian journal of social medicine. Supplementum.

[63]  T. Åkerstedt,et al.  Sleepiness as a consequence of shift work. , 1988, Sleep.

[64]  T Akerstedt,et al.  Sleep/wake disturbances in working life. , 1987, Electroencephalography and clinical neurophysiology. Supplement.

[65]  L Torsvall,et al.  Sleepiness in shiftwork. A review with emphasis on continuous monitoring of EEG and EOG. , 1987, Chronobiology international.

[66]  M. Carskadon,et al.  Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness. , 1986, Sleep.

[67]  B. Tarquini,et al.  Serum gastrin and pepsinogen in shift workers , 1986, International archives of occupational and environmental health.

[68]  G. Richardson,et al.  Medical implications of shift-work. , 1985, Annual review of medicine.

[69]  P. Knauth,et al.  A retrospective cohort study comparing complaints and diseases in day and shift workers , 1980, International archives of occupational and environmental health.

[70]  P Andlauer,et al.  Amplitude of the oral temperature circadian rhythm and the tolerance to shift-work. , 1979, Journal de physiologie.

[71]  H. Eysenck,et al.  AN IMPROVED SHORT QUESTIONNAIRE FOR THE MEASUREMENT OF EXTRAVERSION AND NEUROTICISM. , 1964, Life sciences.