Molecular epidemiology and evaluation of haemato -biochemical parameters in canine parvoviral enteritis dogs in Chennai, India

Canine parvoviral enteritis is caused by canine parvovirus (CPV) which is featured by vomiting, haemorrhagic enteritis, myocarditis, dehydration, dullness and anaemia. It is commonly seen in puppies less than six month of age especially when unvaccinated. An early and accurate diagnosis, proper prophylactic and therapeutic measures, awareness about the pattern of disease occurrences aids the treating veterinarians in a better way. A total of 150 faecal and blood samples were collected from twelve different dog breeds presented with the symptoms of vomiting, haemorrhagic foul smelling diarrhoea and dehydration to Infectious Disease Unit, Madras Veterinary College, Chennai. Polymerase chain reaction was done to estimate the presence of canine parvovirus-2. Out of 150 samples, 71 (47.3%) samples showed positive for canine parvovirus-2. Haemato-biochemical alterations in parvo affected puppies revealed anaemia, leucopenia, decreased packed cell volume, hypoglycemia and decreased electrolyte values. These findings envisage the need for developing proper therapeutic protocols to save the affected puppies.

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