Review: Microfluidic applications in metabolomics and metabolic profiling.
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Charles S Henry | Qian Guan | Ryan E Holcomb | C. Henry | James R Kraly | Ryan E. Holcomb | Qian Guan | James R. Kraly
[1] Angela Man,et al. Toward point-of-care diagnostic metabolic fingerprinting: quantification of plasma creatinine by infrared spectroscopy of microfluidic-preprocessed samples. , 2009, The Analyst.
[2] D. Chiu,et al. High-throughput capillary-electrophoresis analysis of the contents of a single mitochondria. , 2009, Analytical chemistry.
[3] Robert T Kennedy,et al. Continuous-flow enzyme assay on a microfluidic chip for monitoring glycerol secretion from cultured adipocytes. , 2009, Analytical chemistry.
[4] Albert Koulman,et al. From differentiating metabolites to biomarkers , 2009, Analytical and bioanalytical chemistry.
[5] Charles S Henry,et al. Electrode array detector for microchip capillary electrophoresis. , 2009, The Analyst.
[6] G. Chang,et al. A new method for CE-EC determination of mercaptopurine (MP) in a PMMA biochip with on-chip gold nano-electrode ensemble (GNEE) working and decouple electrodes. , 2009, Journal of nanoscience and nanotechnology.
[7] Bingcheng Lin,et al. Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device. , 2009, Lab on a chip.
[8] Wataru Satoh,et al. On-chip culturing of hepatocytes and monitoring their ammonia metabolism. , 2009, Lab on a chip.
[9] He Zhu,et al. A microdevice for multiplexed detection of T-cell-secreted cytokines. , 2008, Lab on a chip.
[10] Yiqing Lin,et al. Microscale LC-MS-NMR platform applied to the identification of active cyanobacterial metabolites. , 2008, Analytical chemistry.
[11] Andreas Manz,et al. Microfluidics: Applications for analytical purposes in chemistry and biochemistry , 2008, Electrophoresis.
[12] S. Wakida,et al. High-throughput assay of nitric oxide metabolites in human plasma without deproteinization by lab-on-a-chip electrophoresis using a zwitterionic additive. , 2008, Journal of chromatography. A.
[13] Joseph F. Clark,et al. Studying protein phosphorylation in low MW CSF fractions with capLC-ICPMS and nanoLC-CHIP-ITMS for identification of phosphoproteins. , 2008, Journal of proteome research.
[14] I. García-Pérez,et al. Metabolic fingerprinting with capillary electrophoresis. , 2008, Journal of chromatography. A.
[15] John P Wikswo,et al. Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel. , 2008, Lab on a chip.
[16] D. Beebe,et al. Microfluidics meet cell biology: bridging the gap by validation and application of microscale techniques for cell biological assays , 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.
[17] Cristina Legido-Quigley,et al. Advances in separation science applied to metabonomics , 2008, Electrophoresis.
[18] Todd Thorsen,et al. Noninvasive metabolic profiling using microfluidics for analysis of single preimplantation embryos. , 2008, Analytical chemistry.
[19] Daniel J Marchiarullo,et al. Towards an integrated microfluidic device for spaceflight clinical diagnostics Microchip-based solid-phase extraction of hydroxyl radical markers. , 2008, Journal of chromatography. A.
[20] R. Ismagilov,et al. Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics. , 2008, Lab on a chip.
[21] Eli J. Weinberg,et al. In vitro analysis of a hepatic device with intrinsic microvascular-based channels , 2008, Biomedical microdevices.
[22] Noritada Kaji,et al. Microchip analysis of plant glucosinolates , 2008, Electrophoresis.
[23] Nam-Trung Nguyen,et al. A lab-on-a-chip for detection of nerve agent sarin in blood. , 2008, Lab on a chip.
[24] Megan N. McClean,et al. Signal processing by the HOG MAP kinase pathway , 2008, Proceedings of the National Academy of Sciences.
[25] Hongkai Wu,et al. Chemical cytometry on microfluidic chips , 2008, Electrophoresis.
[26] Wei-Hua Huang,et al. Recent advances in single-cell analysis using capillary electrophoresis and microfluidic devices. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[27] Yong Xu,et al. A MEMS Thermal Biosensor for Metabolic Monitoring Applications , 2008, Journal of Microelectromechanical Systems.
[28] Terence G. Henares,et al. Current development in microfluidic immunosensing chip. , 2008, Analytica chimica acta.
[29] Jun Wang,et al. Recent advances in electric analysis of cells in microfluidic systems , 2008, Analytical and bioanalytical chemistry.
[30] Charles S Henry,et al. Competitive immunoassays for simultaneous detection of metabolites and proteins using micromosaic patterning. , 2008, Analytical chemistry.
[31] J. Haselden,et al. Metabolic Profiling as a Tool for Understanding Mechanisms of Toxicity , 2008, Toxicologic pathology.
[32] S Gail Eckhardt,et al. NMR-based metabolomics: translational application and treatment of cancer. , 2007, Current opinion in molecular therapeutics.
[33] Ralph G Nuzzo,et al. Mass spectrometric imaging of peptide release from neuronal cells within microfluidic devices. , 2007, Lab on a chip.
[34] Tomoyoshi Soga,et al. Metabolome analysis by capillary electrophoresis-mass spectrometry. , 2007, Journal of chromatography. A.
[35] Martin Pumera,et al. Microfluidics in amino acid analysis , 2007, Electrophoresis.
[36] Laurent Griscom,et al. Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity. , 2007, Toxicology in vitro : an international journal published in association with BIBRA.
[37] Godfrey L. Smith,et al. Microfluidic systems to examine intercellular coupling of pairs of cardiac myocytes. , 2007, Lab on a chip.
[38] Sung-Cheng Huang,et al. In Vivo Quantitation of Glucose Metabolism in Mice Using Small-Animal PET and a Microfluidic Device , 2007, Journal of Nuclear Medicine.
[39] W. Schafer,et al. Multiparallel microfluidic high-performance liquid chromatography for high-throughput normal-phase chiral analysis. , 2007, Journal of chromatography. A.
[40] Man Bock Gu,et al. Fabrication of a bio-MEMS based cell-chip for toxicity monitoring. , 2007, Biosensors & bioelectronics.
[41] Greg E Collins,et al. Simultaneous microchip enzymatic measurements of blood lactate and glucose. , 2007, Analytica chimica acta.
[42] M. Schwarz,et al. Determination of cationic neurotransmitters and metabolites in brain homogenates by microchip electrophoresis and carbon nanotube-modified amperometry. , 2007, Journal of chromatography. A.
[43] Jing‐Juan Xu,et al. Determination of morphine and codeine in urine using poly(dimethylsiloxane) microchip electrophoresis with electrochemical detection. , 2007, Journal of pharmaceutical and biomedical analysis.
[44] Godfrey L. Smith,et al. Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platform. , 2006, Lab on a chip.
[45] C D Mansfield,et al. Integration of microfluidics with biomedical infrared spectroscopy for analytical and diagnostic metabolic profiling. , 2006, IEE proceedings. Nanobiotechnology.
[46] G. Whitesides. The origins and the future of microfluidics , 2006, Nature.
[47] Kristen L. Helton,et al. Microfluidic Overview of Global Health Issues Microfluidic Diagnostic Technologies for Global Public Health , 2006 .
[48] C. Hop. Use of nano-electrospray for metabolite identification and quantitative absorption, distribution, metabolism and excretion studies. , 2006, Current drug metabolism.
[49] S. Wakida,et al. High-throughput nitric oxide assay in biological fluids using microchip capillary electrophoresis. , 2006, Journal of chromatography. A.
[50] Hongyuan Chen,et al. Separation of caffeine and theophylline in poly(dimethylsiloxane) microchannel electrophoresis with electrochemical detection. , 2005, Journal of chromatography. A.
[51] Henk Lingeman,et al. A microfluidic-based enzymatic assay for bioactivity screening combined with capillary liquid chromatography and mass spectrometry. , 2005, Lab on a chip.
[52] R. Bashir,et al. Impedance microbiology-on-a-chip: microfluidic bioprocessor for rapid detection of bacterial metabolism , 2005, Journal of Microelectromechanical Systems.
[53] M. Schwarz,et al. Enzymatic sensitivity enhancement of biogenic monoamines on a chip , 2005, Electrophoresis.
[54] Laura J. Itle,et al. Microreactor Microfluidic Systems with Human Microsomes and Hepatocytes for use in Metabolite Studies , 2005, Biomedical microdevices.
[55] Charles S Henry,et al. Analysis of natural flavonoids by microchip-micellar electrokinetic chromatography with pulsed amperometric detection. , 2005, The Analyst.
[56] Elizabeth Guihen,et al. Rapid separation of antimicrobial metabolites by microchip electrophoresis with UV linear imaging detection. , 2005, Journal of chromatography. A.
[57] A. Mirzabekov,et al. Biosensing and monitoring of cell populations using the hydrogel bacterial microchip. , 2005, Biosensors & bioelectronics.
[58] Pierre Thibault,et al. Integrated microfluidic device for mass spectrometry-based proteomics and its application to biomarker discovery programs. , 2005, Analytical chemistry.
[59] Frank Kohler,et al. Deep UV laser-induced fluorescence detection of unlabeled drugs and proteins in microchip electrophoresis. , 2005, Analytical chemistry.
[60] Qingming Luo,et al. Microfluidic chip toward cellular ATP and ATP-conjugated metabolic analysis with bioluminescence detection. , 2005, Analytical chemistry.
[61] A. Chaudhary,et al. Validating regulatory-compliant wide dynamic range bioanalytical assays using chip-based nanoelectrospray tandem mass spectrometry. , 2005, Rapid communications in mass spectrometry : RCM.
[62] Hidenori Nagai,et al. Simultaneous determination of nitrate and nitrite in biological fluids by capillary electrophoresis and preliminary study on their determination by microchip capillary electrophoresis. , 2004, Journal of chromatography. A.
[63] R. Contreras,et al. Total serum protein N‐glycome profiling on a capillary electrophoresis‐microfluidics platform , 2004, Electrophoresis.
[64] Thomas Laurell,et al. Microfluidic biosensing systems. Part II. Monitoring the dynamic production of glucose and ethanol from microchip-immobilised yeast cells using enzymatic chemiluminescent micro-biosensors. , 2004, Lab on a chip.
[65] David W Piston,et al. Microfluidic glucose stimulation reveals limited coordination of intracellular Ca2+ activity oscillations in pancreatic islets. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[66] Charles S Henry,et al. Direct detection of renal function markers using microchip CE with pulsed electrochemical detection. , 2004, The Analyst.
[67] Elaine Holmes,et al. Metabonomics: systems biology in pharmaceutical research and development. , 2004, Current opinion in molecular therapeutics.
[68] M. Schwarz. Enzyme‐catalyzed amperometric oxidation of neurotransmitters in chip‐capillary electrophoresis , 2004, Electrophoresis.
[69] Charles S. Henry,et al. Enhanced determination of glucose by microchip electrophoresis with pulsed amperometric detection , 2004 .
[70] Mariusz Kowalczyk,et al. A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS. , 2004, Analytical chemistry.
[71] Bifeng Liu,et al. Subsecond separation of cellular flavin coenzymes by microchip capillary electrophoresis with laser-induced fluorescence detection. , 2003, Journal of chromatography. A.
[72] Jun Kameoka,et al. Chip-based P450 drug metabolism coupled to electrospray ionization-mass spectrometry detection. , 2003, Analytical chemistry.
[73] Jack D Henion,et al. Chip-based solid-phase extraction pretreatment for direct electrospray mass spectrometry analysis using an array of monolithic columns in a polymeric substrate. , 2003, Analytical chemistry.
[74] A. Bhunia,et al. Microscale electronic detection of bacterial metabolism , 2002 .
[75] D. Matson,et al. An integrated microfabricated device for dual microdialysis and on-line ESI-ion trap mass spectrometry for analysis of complex biological samples. , 1999, Analytical chemistry.
[76] S. Gygi,et al. An integrated microfluidics-tandem mass spectrometry system for automated protein analysis. , 1998, Analytical chemistry.
[77] P. Zavracky,et al. Multichannel microchip electrospray mass spectrometry. , 1997, Analytical chemistry.
[78] D. Spence,et al. A microfluidic technique for monitoring bloodstream analytes indicative of C-peptide resistance in type 2 diabetes. , 2009, The Analyst.
[79] Guodong Liu,et al. Nanotechnology-based electrochemical sensors for biomonitoring chemical exposures , 2009, Journal of Exposure Science and Environmental Epidemiology.
[80] Wei Du,et al. Microfluidic chips for cell sorting. , 2008, Frontiers in bioscience : a journal and virtual library.
[81] Hirofumi Tani,et al. On-chip bioassay using immobilized sensing bacteria in three-dimensional microfluidic network. , 2007, Methods in molecular biology.
[82] E. J. Song,et al. Capillary electrophoresis at the omics level: Towards systems biology , 2006, Electrophoresis.