Smart Thread Based pH Sensitive Antimicrobial Wound Dressing

Infection monitoring is an important field for wound treatment. This paper presents an engineered smart wound dressing which incorporates pH sensing, wireless smartphone interface and drug delivery components. This system is effective at measuring pH and has a precisely controlled heat-driven drug delivery system. In tests with E. Coli, the smart wound dressing system has been demonstrably effective.

[1]  Ali Khademhosseini,et al.  Dermal Patch with Integrated Flexible Heater for on Demand Drug Delivery , 2016, Advanced healthcare materials.

[2]  H. Matsumura,et al.  Increased wound pH as an indicator of local wound infection in second degree burns. , 2015, Burns : journal of the International Society for Burn Injuries.

[3]  A. Rastogi,et al.  Evaluation of pH measurement as a method of wound assessment. , 2007, Journal of wound care.

[4]  Joachim Dissemond,et al.  Influence of pH on wound-healing: a new perspective for wound-therapy? , 2007, Archives of Dermatological Research.

[5]  Ali Khademhosseini,et al.  A toolkit of thread-based microfluidics, sensors, and electronics for 3D tissue embedding for medical diagnostics , 2016, Microsystems & Nanoengineering.

[6]  R. Rahimi,et al.  Smart Bandage for Monitoring and Treatment of Chronic Wounds. , 2018, Small.

[7]  Mohsen Akbari,et al.  An Advanced Multifunctional Hydrogel‐Based Dressing for Wound Monitoring and Drug Delivery , 2017, Advanced healthcare materials.

[8]  M. Desrosiers,et al.  Effectiveness of Topical Antibiotics on Staphylococcus Aureus Biofilm in Vitro , 2007, American journal of rhinology.

[9]  J. Santy Recognising infection in wounds. , 2008, Nursing Standard.

[10]  K. Cutting Identification of infection in granulating wounds by registered nurses. , 1998, Journal of clinical nursing.

[11]  Gheyath K Nasrallah,et al.  Synthesis, characterization, and antimicrobial properties of novel double layer nanocomposite electrospun fibers for wound dressing applications , 2017, International journal of nanomedicine.