Fundamental Elements for Successful Performance of CT Colonography (Virtual Colonoscopy)

There are many factors affecting the successful performance of CT colonography (CTC). Adequate colonic cleansing and distention, the optimal CT technique and interpretation with using the newest CTC software by a trained reader will help ensure high accuracy for lesion detection. Fecal and fluid tagging may improve the diagnostic accuracy and allow for reduced bowel preparation. Automated carbon dioxide insufflation is more efficient and may be safer for colonic distention as compared to manual room air insufflation. CT scanning should use thin collimation of ≤3 mm with a reconstruction interval of ≤1.5 mm and a low radiation dose. There is not any one correct method for the interpretation of CTC; therefore, readers should be well-versed with both the primary 3D and 2D reviews. Polyps detected at CTC should be measured accurately and reported following the "polyp size-based" patient management system. The time-intensive nature of CTC and the limited resources for training radiologists appear to be the major barriers for implementing CTC in Korea.

[1]  Y. Masutani,et al.  Computerized detection of colonic polyps at CT colonography on the basis of volumetric features: pilot study. , 2002, Radiology.

[2]  Christopher W Seymour,et al.  Anaphylactoid reaction to oral contrast for computed tomography. , 2004, The Journal of trauma.

[3]  Steve Halligan,et al.  Polyp measurement and size categorisation by CT colonography: effect of observer experience in a multi-centre setting , 2006, European Radiology.

[4]  J K Han,et al.  CT colonography in a Korean population with a high residue diet: comparison between wet and dry preparations. , 2006, Clinical radiology.

[5]  L. Weinstock,et al.  Patient Preferences for CT Colonography, Conventional Colonoscopy, and Bowel Preparation , 2003, American Journal of Gastroenterology.

[6]  Judy Yee,et al.  Comparison of supine and prone scanning separately and in combination at CT colonography. , 2003, Radiology.

[7]  E. Paulson,et al.  Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison , 2005, The Lancet.

[8]  R. Jeffrey,et al.  Computed Tomography Colonography: Feasibility of Computer-Aided Polyp Detection in a “First Reader” Paradigm , 2004, Journal of computer assisted tomography.

[9]  K. Huh,et al.  CT colonography using 16-MDCT in the evaluation of colorectal cancer. , 2005, AJR. American journal of roentgenology.

[10]  E G McFarland,et al.  Spiral CT colonography: reader agreement and diagnostic performance with two- and three-dimensional image-display techniques. , 2001, Radiology.

[11]  Perry J Pickhardt,et al.  Patient-controlled room air insufflation versus automated carbon dioxide delivery for CT colonography. , 2006, AJR. American journal of roentgenology.

[12]  M. Hellström,et al.  Availability, indications, and technical performance of computed tomographic colonography: a national survey , 2006, Acta radiologica.

[13]  Michal Amitai,et al.  Actual Colonic Perforation in Virtual Colonoscopy: Report of a Case , 2004, Diseases of the colon and rectum.

[14]  M E Baker,et al.  Computer-aided detection (CAD) for CT colonography: a tool to address a growing need. , 2005, The British journal of radiology.

[15]  R. Jeffrey,et al.  Automated polyp detector for CT colonography: feasibility study. , 2000, Radiology.

[16]  Judy Yee,et al.  Reader training in CT colonography: how much is enough? , 2005, Radiology.

[17]  J. Ferrucci,et al.  Colonoscopy: virtual and optical--another look, another view. , 2005, Radiology.

[18]  I. Bitter,et al.  Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. , 2005, Gastroenterology.

[19]  H. Hoppe,et al.  Virtual colon dissection with CT colonography compared with axial interpretation and conventional colonoscopy: preliminary results. , 2004, AJR. American journal of roentgenology.

[20]  J. Fletcher,et al.  CT colonography using 360° virtual dissection : A feasibility study , 2006 .

[21]  J G Fletcher,et al.  CT colonography without cathartic preparation: feasibility study. , 2001, Radiology.

[22]  J G Fletcher,et al.  CT colonography: unraveling the twists and turns , 2005, Current opinion in gastroenterology.

[23]  P. Pickhardt Incidence of colonic perforation at CT colonography: review of existing data and implications for screening of asymptomatic adults. , 2006, Radiology.

[24]  M. Macari,et al.  ACR Practice Guideline for the Performance of Computerized Tomography (CT) Colonography in Adults , 2009 .

[25]  Steve Halligan,et al.  Potentially serious adverse events at CT colonography in symptomatic patients: national survey of the United Kingdom. , 2006, Radiology.

[26]  S. Laurberg,et al.  Bowel cleansing methods prior to CT-colonography: a prospective, comparative, randomized blinded study , 2002 .

[27]  A. Hara,et al.  Colonic Perforation After Computed Tomographic Colonography in a Patient with Fibrostenosing Crohn's Disease , 2006, The American Journal of Gastroenterology.

[28]  K R Hoffmann,et al.  CT colonography with three-dimensional problem solving for detection of colonic polyps. , 1998, AJR. American journal of roentgenology.

[29]  Perry J Pickhardt,et al.  Linear polyp measurement at CT colonography: in vitro and in vivo comparison of two-dimensional and three-dimensional displays. , 2005, Radiology.

[30]  Marc Baekelandt,et al.  Dietary fecal tagging as a cleansing method before CT colonography: initial results polyp detection and patient acceptance. , 2002, Radiology.

[31]  T. Imperiale,et al.  Meta-analysis and cost comparison of polyethylene glycol lavage versus sodium phosphate for colonoscopy preparation. , 1998, Gastrointestinal endoscopy.

[32]  S. Miller Anaphylactoid reaction after oral administration of diatrizoate meglumine and diatrizoate sodium solution. , 1997, AJR. American journal of roentgenology.

[33]  E. Fishman,et al.  Normal enhancement of the small bowel: evaluation with spiral CT. , 2000, Journal of computer assisted tomography.

[34]  A. Aschoff,et al.  CT colonography: comparison of a colon dissection display versus 3D endoluminal view for the detection of polyps , 2005, European Radiology.

[35]  Abraham H Dachman Advice for optimizing colonic distention and minimizing risk of perforation during CT colonography. , 2006, Radiology.

[36]  Stuart A. Taylor,et al.  Computed tomographic colonography: assessment of radiologist performance with and without computer-aided detection. , 2006, Gastroenterology.

[37]  R. Beart,et al.  Oral fleet® phospho®-soda laxative-induced hyperphosphatemia and hypocalcemic tetany in an adult , 1997, Diseases of the colon and rectum.

[38]  J G Fletcher,et al.  Contrast-enhanced CT colonography in recurrent colorectal carcinoma: feasibility of simultaneous evaluation for metastatic disease, local recurrence, and metachronous neoplasia in colorectal carcinoma. , 2002, AJR. American journal of roentgenology.

[39]  L. P. Angel,et al.  Perforated Colon Secondary to Virtual Colonoscopy: Report of a Case , 2004, Diseases of the colon and rectum.

[40]  S. Park,et al.  False-negative results at multi-detector row CT colonography: multivariate analysis of causes for missed lesions. , 2005, Radiology.

[41]  J. Jackson,et al.  Meta-Analysis: Computed Tomographic Colonography , 2005, Annals of Internal Medicine.

[42]  Jacob Sosna,et al.  Colonic perforation at CT colonography: assessment of risk in a multicenter large cohort. , 2006, Radiology.

[43]  P. Lefere,et al.  The Alternative: Faecal Tagging , 2006 .

[44]  C. Catalano,et al.  Detection of colorectal lesions: lower-dose multi-detector row helical CT colonography compared with conventional colonoscopy. , 2003, Radiology.

[45]  Jamshid Dehmeshki,et al.  Polyp detection with CT colonography: primary 3D endoluminal analysis versus primary 2D transverse analysis with computer-assisted reader software. , 2006, Radiology.

[46]  Joel G Fletcher,et al.  Colonic perforation at CT colonography in a patient without known colonic disease. , 2006, AJR. American journal of roentgenology.

[47]  Steve Halligan,et al.  Optimizing colonic distention for multi-detector row CT colonography: effect of hyoscine butylbromide and rectal balloon catheter. , 2003, Radiology.

[48]  J. V. van Engelshoven,et al.  Patient and occupational dosimetry in double contrast barium enema examinations. , 2001, The British journal of radiology.

[49]  S. Laurberg,et al.  Bowel cleansing methods prior to CT colonography. , 2002, Acta radiologica.

[50]  J. Burdick,et al.  Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. , 2004, JAMA.

[51]  Jonathan B. Kruskal,et al.  CT colonography: colonic distention improved by dual positioning but not intravenous glucagon , 2002, European Radiology.

[52]  J. Yee,et al.  CT colonography reporting and data system: a consensus proposal. , 2005, Radiology.

[53]  Joel G Fletcher,et al.  CT colonography using 360-degree virtual dissection: a feasibility study. , 2006, AJR. American journal of roentgenology.

[54]  Aytekin Oto,et al.  CT attenuation of colorectal polypoid lesions: evaluation of contrast enhancement in CT colonography , 2003, European Radiology.

[55]  Philippe Lefere,et al.  Laxative-free CT colonography. , 2004, AJR. American journal of roentgenology.

[56]  P. Pickhardt,et al.  Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. , 2003, The New England journal of medicine.

[57]  Philippe Lefere,et al.  CT colonography after fecal tagging with a reduced cathartic cleansing and a reduced volume of barium. , 2005, AJR. American journal of roentgenology.

[58]  Carlo Catalano,et al.  Computed tomographic colonography without cathartic preparation for the detection of colorectal polyps. , 2004, Gastroenterology.

[59]  A. Vecchione,et al.  Contrast-enhanced computed tomographic colonography in the follow-up of colorectal cancer patients: a feasibility study , 2003, European Radiology.

[60]  J R Hecht,et al.  CT colonography: value of scanning in both the supine and prone positions. , 1999, AJR. American journal of roentgenology.

[61]  P. Lefere,et al.  Virtual colonoscopy : a practical guide , 2006 .

[62]  M. Macari,et al.  Comparison of time-efficient CT colonography with two- and three-dimensional colonic evaluation for detecting colorectal polyps. , 2000, AJR. American journal of roentgenology.

[63]  J. E. Lee,et al.  Efficacy of CT Colonography in the Detection of Colorectal Polypoid Lesions , 2005 .

[64]  CT colonography: contrast enhancement of benign and malignant colorectal lesions versus fecal residuals , 2005, Abdominal Imaging.

[65]  J. Kruskal,et al.  Utility of intravenously administered contrast material at CT colonography. , 2000, Radiology.

[66]  Michael E. Zalis,et al.  Digital subtraction bowel cleansing for CT colonography using morphological and linear filtration methods , 2004, IEEE Transactions on Medical Imaging.

[67]  Perry J Pickhardt,et al.  Electronic cleansing and stool tagging in CT colonography: advantages and pitfalls with primary three-dimensional evaluation. , 2003, AJR. American journal of roentgenology.