PEA3 transcription factors are expressed in tissues undergoing branching morphogenesis and promote formation of duct-like structures by mammary epithelial cells in vitro.

[1]  J. Thiery.  Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.

[2]  J. Yang,et al.  Signal transduction-mediated regulation of urokinase gene expression in human prostate cancer. , 2001, Biochemical and biophysical research communications.

[3]  P. Dollé,et al.  Expression patterns of the Ets transcription factors from the PEA3 group during early stages of mouse development , 2001, Mechanisms of Development.

[4]  M. Nishimura,et al.  Expression of E1AF/PEA3, an Ets‐related transcription factor in human non‐small‐cell lung cancers: Its relevance in cell motility and invasion , 2001, International journal of cancer.

[5]  S. Nigam,et al.  Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis. , 2001, Development.

[6]  K. Subbaramaiah,et al.  PEA3 Is Up-regulated in Response to Wnt1 and Activates the Expression of Cyclooxygenase-2* , 2001, The Journal of Biological Chemistry.

[7]  M. Post,et al.  The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development. , 2001, Development.

[8]  M. Trojanowska.  Ets factors and regulation of the extracellular matrix , 2000, Oncogene.

[9]  Ioanna G Maroulakou,et al.  Expression and function of Ets transcription factors in mammalian development: a regulatory network , 2000, Oncogene.

[10]  R. Montesano,et al.  Expression of an activated Notch4(int‐3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro , 2000, International journal of cancer.

[11]  E. Lengyel,et al.  Activation Mechanisms of the Urokinase-type Plasminogen Activator Promoter by Hepatocyte Growth Factor/Scatter Factor* , 1999, The Journal of Biological Chemistry.

[12]  J. Hamada,et al.  Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression , 1999, Oncogene.

[13]  R. Neve,et al.  The epithelium‐specific Ets transcription factor ESX is associated with mammary gland development and involution , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[14]  J. Baert,et al.  The transcription of the intercellular adhesion molecule-1 is regulated by Ets transcription factors , 1998, Oncogene.

[15]  R. Montesano,et al.  Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion. , 1998, Developmental biology.

[16]  B. Hogan,et al.  Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. , 1997, Development.

[17]  Y. Totsuka,et al.  Expression of E1AF, an ets-family transcription factor, is correlated with the invasive phenotype of oral squamous cell carcinoma. , 1997, Oral Oncology.

[18]  P. Defossez,et al.  The ETS family member ERM contains an alpha-helical acidic activation domain that contacts TAFII60. , 1997, Nucleic acids research.

[19]  P. Defossez,et al.  Differential expression patterns of the PEA3 group transcription factors through murine embryonic development , 1997, Oncogene.

[20]  P. Defossez,et al.  Structure-function relationships of the PEA3 group of Ets-related transcription factors. , 1997, Biochemical and molecular medicine.

[21]  Y. Totsuka,et al.  Antisense E1AF transfection restrains oral cancer invasion by reducing matrix metalloproteinase activities. , 1997, The American journal of pathology.

[22]  B. Vandenbunder,et al.  The ETS1 transcription factor is expressed during epithelial-mesenchymal transitions in the chick embryo and is activated in scatter factor-stimulated MDCK epithelial cells. , 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[23]  R. Sutherland,et al.  Expression of the PEA3 group of ETS‐related transcription factors in human breast‐cancer cells , 1997, International journal of cancer.

[24]  C. Worby,et al.  Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[25]  P. Ekblom.  Genetics of kidney development. , 1996, Current opinion in nephrology and hypertension.

[26]  L. Orci,et al.  TGF-beta1 induces morphogenesis of branching cords by cloned mammary epithelial cells at subpicomolar concentrations. , 1996, Biochemical and biophysical research communications.

[27]  P. Defossez,et al.  Two functionally distinct domains responsible for transactivation by the Ets family member ERM. , 1996, Oncogene.

[28]  T. Kohgo,et al.  Correlated expression of matrix metalloproteinases and ets family transcription factor E1A-F in invasive oral squamous-cell-carcinoma-derived cell lines. , 1996, The American journal of pathology.

[29]  F. Higashino,et al.  A single ets-related transcription factor, E1AF, confers invasive phenotype on human cancer cells. , 1996, Oncogene.

[30]  T. Noumi,et al.  Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters. , 1995, Oncogene.

[31]  L. Orci,et al.  Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. , 1995, Journal of cell science.

[32]  A. Vaahtokari,et al.  Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. , 1995, The International journal of developmental biology.

[33]  W. Muller,et al.  PEA3 is overexpressed in mouse metastatic mammary adenocarcinomas. , 1993, Oncogene.

[34]  H. Sato,et al.  Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. , 1993, Oncogene.

[35]  L. Orci,et al.  Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. , 1992, Biochemical and biophysical research communications.

[36]  L. Orci,et al.  Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor , 1991, Cell.

[37]  C. Stratowa,et al.  Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5'-regulatory region. Induction by cytokines and phorbol ester. , 1991, Journal of immunology.

[38]  B. Wasylyk,et al.  The c‐Ets oncoprotein activates the stromelysin promoter through the same elements as several non‐nuclear oncoproteins. , 1991, The EMBO journal.

[39]  B. Wasylyk,et al.  The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation , 1990, Nature.

[40]  B. Wasylyk,et al.  The collagenase gene promoter contains a TPA and oncogene‐responsive unit encompassing the PEA3 and AP‐1 binding sites. , 1990, The EMBO journal.

[41]  L. Opperman,et al.  Induction of supernumerary tracheal buds and the stimulation of DNA synthesis in the embryonic chick lung and trachea by epidermal growth factor. , 1980, Journal of embryology and experimental morphology.

[42]  B. Graves,et al.  Specificity within the ets family of transcription factors. , 1998, Advances in cancer research.

[43]  W. Birchmeier,et al.  Epithelial-mesenchymal transitions in cancer progression. , 1996, Acta anatomica.

[44]  K. Roebuck,et al.  H2O2 and tumor necrosis factor-alpha activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter. , 1995, The Journal of biological chemistry.

[45]  B. Wasylyk,et al.  The Ets family of transcription factors. , 1993, European journal of biochemistry.

[46]  C. Daniel,et al.  Postnatal Development of the Rodent Mammary Gland , 1987 .

[47]  M. Neville,et al.  The Mammary gland : development, regulation, and function , 1987 .

[48]  C. Grobstein.  Inductive tissue interaction in development. , 1956, Advances in cancer research.